Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel

Life Sciences

Volumn 82, Issue 5-6, 2008, Pages 331-340

  Jo, Su Hyun ^a   Hong, Hee Kyung ^a   Chong, Seon Ha ^b   Choe, Han ^b  

^a Kangwon National University College of Medicine   (South Korea)

^b University of Ulsan College of Medicine   (South Korea)

Author keywords

Arrhythmias; HERG channel; Long QT syndrome; Protriptyline; Tricyclic antidepressant

Indexed keywords

POTASSIUM CHANNEL HERG; PROTRIPTYLINE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; HUMAN; HUMAN CELL; IC 50; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; STEADY STATE; XENOPUS;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CELL LINE; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; INHIBITORY CONCENTRATION 50; KIDNEY; LONG QT SYNDROME; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNEL BLOCKERS; PROTRIPTYLINE; XENOPUS LAEVIS;

EID: 38349060542     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.12.004     Document Type: Article

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