Additive effects of ziprasidone and D,L-sotalol on the action potential in rabbit Purkinje fibres and on the hERG potassium current

Journal of Pharmacological and Toxicological Methods

Volumn 52, Issue 1, 2005, Pages 115-122

  Ducroq, Joffrey ^a   Printemps, Richard ^a   Le Grand, Marie ^a  

^a Physiostim ZI de Brénas Lautrec ^*  (France)

Author keywords

Action potential; Additive effects; APD90; D,L sotalol; HEK 293 cells; hERG current; Interaction; Methods; Rabbit Purkinje fibres; Ziprasidone

Indexed keywords

POTASSIUM CHANNEL; SOTALOL; ZIPRASIDONE;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; FREQUENCY MODULATION; MUSCLE ACTION POTENTIAL; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PURKINJE FIBER; QT PROLONGATION;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ANTIPSYCHOTIC AGENTS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; FEMALE; HUMANS; ORGAN CULTURE TECHNIQUES; PERFUSION; PIPERAZINES; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, VOLTAGE-GATED; PURKINJE FIBERS; RABBITS; SOTALOL; THIAZOLES;

ORYCTOLAGUS CUNICULUS;

EID: 22444432007     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2005.04.001     Document Type: Article

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