Identification of Tumor Necrosis Factor (TNF) Amino Acids Crucial for Binding to the Murine p75 TNF Receptor and Construction of Receptor-selective Mutants

Journal of Biological Chemistry

Volumn 276, Issue 40, 2001, Pages 37426-37430

  Ameloot, Paul ^a   Fiers, Walter ^a   De Bleser, Pieter ^a   Ware, Carl F ^b   Vandenabeele, Peter ^a   Brouckaert, Peter ^a,c  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Dept of Molecular Biology ^*  (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; HUMAN ENGINEERING; TOXICITY; TUMORS;

TUMOR NECROSIS FACTORS (TNF);

BIOCHEMISTRY;

AMINO ACID; CHIMERIC PROTEIN; HUMAN TUMOR NECROSIS FACTOR S71D TY2Y H73DELTA T89E PROTEIN; MURINE TUMOR NECROSIS FACTOR D71S Y72T DELTA73H E89T P102Q PROTEIN; MUTANT PROTEIN; MUTEIN; OLIGOMER; PROTEIN P75; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR I; TUMOR NECROSIS FACTOR RECEPTOR II; UNCLASSIFIED DRUG; HYBRID PROTEIN; LEUKOCYTE ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; CELL ASSAY; CELL PROLIFERATION; CYTOTOXICITY; DISSOCIATION; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN STABILITY; RECEPTOR AFFINITY; RECEPTOR BINDING; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; GEL CHROMATOGRAPHY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION;

ANIMALIA; MURINAE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; CHROMATOGRAPHY, GEL; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; RECOMBINANT FUSION PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035813225     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102020200     Document Type: Article

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