메뉴 건너뛰기




Volumn 39, Issue 6, 2007, Pages 812-819

Interleukin-10 endogenously expressed in microglia prevents lipopolysaccharide-induced neurodegeneration in the rat cerebral cortex in vivo

Author keywords

Inflammation; Interleukin 10; Lipopolysaccharide; Microglia; NADPH oxidase; Neuron; Reactive oxygen species

Indexed keywords

INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; NEUTRALIZING ANTIBODY; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TUMOR NECROSIS FACTOR ALPHA;

EID: 38049141246     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2007.88     Document Type: Article
Times cited : (78)

References (30)
  • 1
    • 0035487313 scopus 로고    scopus 로고
    • Cytokines and acute neurodegeneration
    • Allan SM, Rothwell NJ. Cytokines and acute neurodegeneration. Nat Rev Neurosci 2001;2:734-44
    • (2001) Nat Rev Neurosci , vol.2 , pp. 734-744
    • Allan, S.M.1    Rothwell, N.J.2
  • 2
    • 0031571317 scopus 로고    scopus 로고
    • IL-12 production by central nervous system microglia is inhibited by astrocytes
    • Aloisi F, Penna G, Cerase J, Menendez Iglesias B, Adorini L. IL-12 production by central nervous system microglia is inhibited by astrocytes. J Immunol 1997;159:1604-12
    • (1997) J Immunol , vol.159 , pp. 1604-1612
    • Aloisi, F.1    Penna, G.2    Cerase, J.3    Menendez Iglesias, B.4    Adorini, L.5
  • 3
    • 0033564234 scopus 로고    scopus 로고
    • Opposite effects of interferon-γ and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: A regulatory loop controlling microglia pro- and anti-inflammatory activities
    • Aloisi F, De Simone R, Columba-Cabezas S, Levi G. Opposite effects of interferon-γ and prostaglandin E2 on tumor necrosis factor and interleukin-10 production in microglia: a regulatory loop controlling microglia pro- and anti-inflammatory activities. J Neurosci Res 1999a;56:571-80
    • (1999) J Neurosci Res , vol.56 , pp. 571-580
    • Aloisi, F.1    De Simone, R.2    Columba-Cabezas, S.3    Levi, G.4
  • 4
    • 0033083789 scopus 로고    scopus 로고
    • CD40-CD154 interaction and IFN-γ are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells
    • Aloisi F, Penna G, Polazzi E, Minghetti L, Adorini L. CD40-CD154 interaction and IFN-γ are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells. J Immunol 1999b;162:1384-91
    • (1999) J Immunol , vol.162 , pp. 1384-1391
    • Aloisi, F.1    Penna, G.2    Polazzi, E.3    Minghetti, L.4    Adorini, L.5
  • 5
    • 0035152836 scopus 로고    scopus 로고
    • Immune function of microglia
    • Aloisi F. Immune function of microglia. Glia 2001;36:165-79
    • (2001) Glia , vol.36 , pp. 165-179
    • Aloisi, F.1
  • 7
  • 8
    • 33845768784 scopus 로고    scopus 로고
    • Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
    • Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 2007;8:57-69
    • (2007) Nat Rev Neurosci , vol.8 , pp. 57-69
    • Block, M.L.1    Zecca, L.2    Hong, J.S.3
  • 9
    • 0032837804 scopus 로고    scopus 로고
    • Postischemic hypothermia and IL-10 treatment provide long-lasting neuroprotection of CA1 hippocampus following transient global ischemia in rats
    • Dietrich WD, Busto R, Bethea JR. Postischemic hypothermia and IL-10 treatment provide long-lasting neuroprotection of CA1 hippocampus following transient global ischemia in rats. Exp Neurol 1999:158:444-50
    • (1999) Exp Neurol , vol.158 , pp. 444-450
    • Dietrich, W.D.1    Busto, R.2    Bethea, J.R.3
  • 10
    • 34547127632 scopus 로고    scopus 로고
    • Neuroprotective role of the innate immune system by microglia
    • Glezer I, Simard AR, Rivest S. Neuroprotective role of the innate immune system by microglia. Neuroscience 2007;147:867-83
    • (2007) Neuroscience , vol.147 , pp. 867-883
    • Glezer, I.1    Simard, A.R.2    Rivest, S.3
  • 12
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: Active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch UK, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci 2007;10:1387-94
    • (2007) Nat Neurosci , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 13
    • 0031713714 scopus 로고    scopus 로고
    • Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury
    • Knoblach SM, Faden AI. Interleukin-10 improves outcome and alters proinflammatory cytokine expression after experimental traumatic brain injury. Exp Neurol 1998;153:143-51
    • (1998) Exp Neurol , vol.153 , pp. 143-151
    • Knoblach, S.M.1    Faden, A.I.2
  • 14
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg GW. Microglia: a sensor for pathological events in the CNS. Trends Neurosci 1996;19: 312-8
    • (1996) Trends Neurosci , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 15
    • 0034032594 scopus 로고    scopus 로고
    • Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in cocultures of rat astroglial and microglial cells
    • Ledeboer A, Breve JJ, Poole S, Tilders FJ, Van Dam AM. Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in cocultures of rat astroglial and microglial cells. Glia 2000;30:134-42
    • (2000) Glia , vol.30 , pp. 134-142
    • Ledeboer, A.1    Breve, J.J.2    Poole, S.3    Tilders, F.J.4    Van Dam, A.M.5
  • 16
    • 0036644961 scopus 로고    scopus 로고
    • Cytokines, chemokines, and cytokine receptors in human microglia
    • Lee YB, Nagai A, Kim SU. Cytokines, chemokines, and cytokine receptors in human microglia. J Neurosci Res 2002;69:94-103
    • (2002) J Neurosci Res , vol.69 , pp. 94-103
    • Lee, Y.B.1    Nagai, A.2    Kim, S.U.3
  • 17
    • 30444459031 scopus 로고    scopus 로고
    • The role of inflammation in CNS injury and disease
    • Lucas SM, Rothwell NJ, Gibson RM. The role of inflammation in CNS injury and disease. Br J Pharmacol 2006;147:232-40
    • (2006) Br J Pharmacol , vol.147 , pp. 232-240
    • Lucas, S.M.1    Rothwell, N.J.2    Gibson, R.M.3
  • 18
    • 27344458546 scopus 로고    scopus 로고
    • Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: A dual-key mechanism of inflammatory neurodegeneration
    • Mander P, Brown GC. Activation of microglial NADPH oxidase is synergistic with glial iNOS expression in inducing neuronal death: a dual-key mechanism of inflammatory neurodegeneration. J Neuroinflammation 2005;2:20-34
    • (2005) J Neuroinflammation , vol.2 , pp. 20-34
    • Mander, P.1    Brown, G.C.2
  • 19
    • 2442532533 scopus 로고    scopus 로고
    • How the brain repairs itself: New therapeutic strategies in inflammatory and degenerative CNS disorders
    • Martino G. How the brain repairs itself: new therapeutic strategies in inflammatory and degenerative CNS disorders. Lancet Neurol 2004;3:372-8
    • (2004) Lancet Neurol , vol.3 , pp. 372-378
    • Martino, G.1
  • 21
    • 0036518997 scopus 로고    scopus 로고
    • Innate immunity: The missing link in neuroprotection and neurodegeneration?
    • Nguyen MD, Julien JP, Rivest S. Innate immunity: the missing link in neuroprotection and neurodegeneration? Nat Rev Neurosci 2002;3:216-27
    • (2002) Nat Rev Neurosci , vol.3 , pp. 216-227
    • Nguyen, M.D.1    Julien, J.P.2    Rivest, S.3
  • 22
    • 33846585119 scopus 로고    scopus 로고
    • Systemic infections and inflammation affect chronic neurodegeneration
    • Perry VH, Cunningham C, Holmes C. Systemic infections and inflammation affect chronic neurodegeneration. Nat Rev Immunol 2007;7:161-7
    • (2007) Nat Rev Immunol , vol.7 , pp. 161-167
    • Perry, V.H.1    Cunningham, C.2    Holmes, C.3
  • 23
    • 33749036329 scopus 로고    scopus 로고
    • Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase
    • Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase. J Pharmacol Exp Ther 2006;319:44-52
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 44-52
    • Qian, L.1    Block, M.L.2    Wei, S.J.3    Lin, C.F.4    Reece, J.5    Pang, H.6    Wilson, B.7    Hong, J.S.8    Flood, P.M.9
  • 24
    • 0346463000 scopus 로고    scopus 로고
    • NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
    • Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS. NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. J Biol Chem 2004;279:1415-21
    • (2004) J Biol Chem , vol.279 , pp. 1415-1421
    • Qin, L.1    Liu, Y.2    Wang, T.3    Wei, S.J.4    Block, M.L.5    Wilson, B.6    Liu, B.7    Hong, J.S.8
  • 25
    • 0032996810 scopus 로고    scopus 로고
    • Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia
    • Sawada M, Suzumura A, Hosoya H, Marunouchi T, Nagatsu T. Interleukin-10 inhibits both production of cytokines and expression of cytokine receptors in microglia. J Neurochem 1999;72:1466-71
    • (1999) J Neurochem , vol.72 , pp. 1466-1471
    • Sawada, M.1    Suzumura, A.2    Hosoya, H.3    Marunouchi, T.4    Nagatsu, T.5
  • 26
    • 2442718746 scopus 로고    scopus 로고
    • Interleukin-10 expression in lipopolysaccharide- activated microglia is mediated by extracellular ATP in an autocrine fashion
    • Seo DR, Kim KY, Lee YB. Interleukin-10 expression in lipopolysaccharide- activated microglia is mediated by extracellular ATP in an autocrine fashion. Neuroreport 2004;15:1157-61
    • (2004) Neuroreport , vol.15 , pp. 1157-1161
    • Seo, D.R.1    Kim, K.Y.2    Lee, Y.B.3
  • 28
    • 0037947448 scopus 로고    scopus 로고
    • Wu DC, Teismann P, Tieu K, Vila M, Jackson-Lewis V, Ischiropoulos H, Przedborski S. NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Proc Natl Acad Sci USA 2003;100:6145-50
    • Wu DC, Teismann P, Tieu K, Vila M, Jackson-Lewis V, Ischiropoulos H, Przedborski S. NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Proc Natl Acad Sci USA 2003;100:6145-50
  • 29
    • 33747047814 scopus 로고    scopus 로고
    • The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
    • Wu DC, Re DB, Nagai M, Ischiropoulos H, Przedborski S. The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proc Natl Acad Sci USA 2006;103:12132-7
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 12132-12137
    • Wu, D.C.1    Re, D.B.2    Nagai, M.3    Ischiropoulos, H.4    Przedborski, S.5
  • 30
    • 33747890559 scopus 로고    scopus 로고
    • The brain as a target of inflammation: Common pathways link inflammatory and neurodegenerative diseases
    • Zipp F, Aktas O. The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases. Trends Neurosci 2006;29:518-27
    • (2006) Trends Neurosci , vol.29 , pp. 518-527
    • Zipp, F.1    Aktas, O.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.