IL-10 production by adult human derived microglial cells

Neurochemistry International

Volumn 29, Issue 1, 1996, Pages 55-64

  Williams, K ^a   Dooley, N ^b   Ulvestad, E ^c   Becher, B ^b   Antel, J P ^b  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF BERGEN   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 10; LIPOPOLYSACCHARIDE;

ALLERGIC ENCEPHALOMYELITIS; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CELL STIMULATION; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; HUMAN CELL; IMMUNITY; LISTERIA MONOCYTOGENES; MACROPHAGE; MICROGLIA; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0030198917     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/0197-0186(95)00138-7     Document Type: Article

References (56)

1. Abrams J.S., Roncarolo H., Yssel H., Anderson U.M., Gleich G.J., Silver J. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol. Rev. 127:1992;5-22.
2. Adams C.W.M. (1983) The general pathology of multiple sclerosis: morphological and chemical aspects of the lesions. In Multiple sclerosis (Hallpike J.F., Adams C.W.M. and Tourtellotte W.W., eds), pp. 203-240. Cambridge University Press, Cambridge.
3. Arcari P., Martinelli R., Salvatore F. The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species. Nucl. Acids Res. 12:1984;9179-9190.
4. Banati R.B., Gehrmann J., Schubert P., Kreutzberg G.W. Cytotoxicity of microglia. Glia. 7:1993;111-118.
5. Bejarano M.T., de Waal Malefyt R., Abrams J.S., Bigler M., Bacchetta R., de Vries J.R., Roncarolo M-G. Interleukin 10 inhibits allogenic, proliferative, and cytotoxic T-cell responses generated in primary mixed lymphocyte cultures. Int. Immunol. 4:1992;1389-1397.
6. Bö L., Mork S., Kong P.A., Nyland H., Pardo C.A., Trapp B.D. Detection of MHC class II antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions. J. Neuro-immunol. 51:1994;135-146.
7. Bogdan C., Vodovotz Y., Nathan C. Macrophage deactivation by interleukin 10. J. Exp. Med. 174:1991;1549-1555.
8. Cannella B., Cross A.H., Raine C.D. Upregulation and coexpression of adhesion molecules correlates with relapsing autoimmune demyelination in the central nervous system. J. Exp. Med. 172:1990;1521-1524.
9. Chen Y., Kuchroo V.K., Inobe J., Hafler D.A., Weiner H.L. Regulatory T-cells clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science. 265:1994;1237-1240.
10. Chomczynaki P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
11. Colton C.A., Gilbert D.L. Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett. 223:1987;284-288.
12. Dickson D.W., Mattiace L.A., Kure K., Hutchins K., Lyman W.D., Brosnan C.F. Biology of disease: microglia in human disease, with an emphasis on acquired immune deficiency syndrome. Lab. Invest. 64:1991;135-156.
13. Fiorentino D.F., Zlotnik A., Mosmann T.R., Howard M., O'Garra A. IL-10 inhibits cytokine production by activated macrophages. J. Immunol. 147:1991;3815-3822.
14. Fiorentino D.F., Zlotnik A., Viera P., Mossmann T.R., Howard M., Moore K.W., O'Garra A (1991b) IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J. Immunol. 146:1991;3444-3451.
15. Frei K., Lins H., Schwerdel C., Fontana A. Antigen presentation in the central nervous system. The inhibitory effect of IL-10 on MHC class II expression and production of cytokines depends on the inducing signals and type of cell analyzed. J. Immunol. 152:1993;2720-2708.
16. Frei K., Nadal D., Pfister H.W., Fontana A. Listeria meningitis: identification of a cerebrospinal fluid inhibitor of macrophage listericidal function as interleukin 10. J. Exp. Med. 178:1993;1255-1261.
17. Graeber M.B., Bise K., Mehraein P. CR3/43, a marker for activated human microglia: application to diagnostic neuropathology. Neuropath. Appl. Neurobiol. 20:1994;406-408.
18. Hickey W.F., Kimura H. Perivascular microglia are bone marrow derived and present antigen in vivo. Science. 239:1988;290-292.
19. Howard M., O'Garra A. Biological properties of interleukin 10. Immunol. Today. 13:1992;198-200.
20. Huitinga I., Damoiseaux J.G., Dopp E.A., Dijkstra C.D. Treatment with anti-CR3 antibodies ED7 and ED8 suppresses experimental allergic encephalomyelitis in Lewis rats. Eur. J. Immunol. 23:1993;709-715.
21. Huitinga I., van Rooijen N., de Groot C.J.A., Uitdehaag B.M.J., Dijkstra C.D. Elimination of macrophages infiltrating the CNS suppresses EAE in rats. J. Exp. Med. 172:1990;1025-1033.
22. Itagaki S., McGeer P.P., Akiyama H. Presence of cytotoxic suppressor and leukocyte common antigen positive cells in Alzheimer disease brain tissue. Neurosci. Lett. 91:1988;259-261.
23. Kennedy M.K., Torrance D.S., Picha K.A., Mohler K.M. Analysis of cytokine mRNA expression in the central nervous system of mice with experimental auto-immune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery. J. Immunol. 49:1992;2496-2505.
24. Lassmann H., Rossler K., Zimprich F., Vass K. Expression of adhesion molecules and histocompatibility antigens at the blood-brain barrier. Brain Pathol. 1:1991;115-123.
25. Lassmann H., Schmied M., Vass K., Hickey W.F. Bone marrow derived elements and resident microglia in brain inflammation. Glia. 7:1993;19-24.
26. Ling B-A., Wong W-C. The origin and nature of ramified and ameboid microglia: a historical review and current concept. Glia. 7:1993;9-18.
27. Linington C., Bradi M., Lassmann H. Augmentation of demyelination in rat acute experimental allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin-oligodendrocyte glycoprotein. Am. J. Pathol. 130:1988;443-454.
28. Linington C., Lassmann H. Antibody response in clinical relapsing experimental allergic encephalomyelitis: correlation of serum demyelinating activity with antibody titer to myelin/oligodendrocyte glycoprotein (MOG). J. Neuroimmunol. 17:1987;61-69.
29. Link H., Baigs S., Olsson O., Jian Y.P., Hojeberg B., Olsson T. Persistent anti-myelin basic protein IgG antibody response in multiple sclerosis cerebral spinal fluid. J. Neuroimmunol. 28:1990;237-238.
30. Macatonia S.E., Doherty T.M., Knoght S.C., O'Garra A. Differential effect of IL-10 on dendritic cell-induced T-cell proliferation and IFNγ production. J. Immunol. 150:1993;3755-3765.
31. Rossler K., Neuchrist C., Kitz K., Scheiner O., Kraft D., Lassmann H. Expression of leucocyte adhesion molecules at the human blood-brain barrier (BBB). J. Neurosci. Res. 31:1992;365-374.
32. Rott O., Fleischer B., Cash E. Interleukin-10 prevents experimental allergic encephalomyelitis in rats. Eur. J. Immunol. 24:1994;1434-1440.
33. Ruddle N.H., Bergmann C.M., McGrath K.M., Lingenheld E.G., Grunnet M.L., Padula S.J., Clark R.B. An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis. J. Exp. Med. 172:1990;1193-1200.
34. Scolding N.J.M., Compston D.A.S. Oligodendrocyte macrophage interactions in vitro triggered by specific antibodies. Immunology. 72:1991;127-132.
35. + T lymphocytes correlate with down regulation of THl cytokine synthesis in helminth infection. J. Immunol. 147:1991;2713-2719.
36. Singer-Sam J., Robinson M.O., Belve A.R., Simon M.I., Rigg D.G. Measurement by quantitative PCR of changes in HPRT, PGK-1, APRT, MTases and ZFY gene transcripts during mouse spermatogenesis. Nucl. Acid Res. 18:1991;1255-1259.
37. Theele D.P., Streit W.J. A chronicle of microglial ontogeny. Glia. 7:1993;5-8.
38. Thomas W.E. Brain macrophages: evaluation of microglia and their functions. Brain Res. Rev. 17:1992;61-74.
39. Ulvestad E., Williams K., Matre R., Nyland H., Olivier A., Antel J. Fc receptors for IgG on cultured human microglia mediate cytotoxicity and phagocytosis and antibody-coated targets. J. Neuropath. Exp. Neurol. 53:1994;27-36.
40. Ulvestad E., Williams K., Mork S., Antel J., Nyland H. Phenotypic differences between human monocytes/macrophages and microglial cells studied in situ and in vitro. J. Neuropath. Exp. Neurol. 53:1994;492-501.
41. Ulvestad E., Williams K., Bjerkvig R., Teikotter K., Antel J., Matre R. Human microglial cells have phenotypic and functional characteristics in common with both macrophages and dendritic antigen presenting cells. J. Leuk. Bio. 56:1994;732-740.
42. Ulvestad E., Williams K., Bo L., Trapp B., Antel J., Mork S. HLA class II molecules (HLA-DR, DP, DQ) on cells in the human CNS studied in situ and in vitro. Immunology. 82:1994;535-541.
43. Ulvestad E., Williams K., Vedler C., Antel J., Nyland H., Morke S., Matre R. Reactive microglia in multiple sclerosis lesions have an increased expression of receptors for the Fc part of IgG. J. Neurol. Sci. 121:1994;125-131.
44. Unanue E.R., Allen P.M. The basis for immuno-regulatory role of macrophages and other accessory cells. Science. 236:1987;551-556.
45. Unger E.R., Sung J.H., Manivel J.C., Chenggis M.L., Blazar B.R. Male donor-derived cells in the brains of female sex-mismatched bone marrow transplant recipients: a Y-chromosome specific in situ hybridization study. J. Neuropath. Exp. Neurol. 52:1993;460-470.
46. Viera P., de Waal-Malefyt R., Dang M.N., Johnson K.E., Kastelein R., Fiorentino D.F., de Vries J.E., Roncarolo M.G., Mosmann T.R., Moore K.W. Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc. natn. Acad. Sci. USA. 88:1991;1172-1176.
47. de Waal Nalefyt R., Abrams J., Bennett B., Figdor C.G., de Vries J.E. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an auto-regulatory role of IL-10 produced by monocytes. J. Exp. Med. 174:1991;1209-1220.
48. Wanidworanun C., Strober W. Predominant role of tumor necrosis factor-α in human monocyte IL-10 synthesis. J. Immunol. 151:1993;6853-6861.
49. Willems F., Marchant A., Delville J-P., Gerard C., Delvaux A., Velu T., de Boer M., Goldman M. Interleukin-10 inhibits B7 and intercellular adhesion molecule-I expression on human monocytes. Eur. J. Immunol. 24:1994;1007-1009.
50. Williams K., Bar-Or A., Ulvestad E., Olivier A., Antel J.P., Yong V.W. Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes. J. Neuropathol. Exp. Neurol. 51:1992;538-549.
51. Williams K., Dooley N., Ulvestad B., Waage A., Blain M., Yong V.W., Antel J. Antigen presentation by human fetal astrocytes with the cooperative effect of microglia or the microglial derived cytokine IL-1. J. Neurosci. 15:1995;1869-1871.
52. Williams K., Ulvestad B., Antel J. Immune regulatory and effector properties of human adult microglia studied in vitro and in situ. Adv. Neuroimmunol. 4:1994;273-281.
53. Williams K., Ulvestad B., Antel J.P. B7/BB-1 expression on adult human microglia studied in vitro and in situ. Eur. J. Immunol. 24:1994;3031-3037.
54. Williams K., Ulvestad B., Cragg L., Blain M., Antel J.P. Induction of primary T-cell responses by human glial cells. J. Neurosci Res. 36:1993;382-390.
55. Williams K., Ulvestad B., Waage A., Antel W., McLaurin J. Activation of adult human derived microglia by myelin phagocytosis in vitro. J. Neurosci Res. 38:1994;433-443.
56. Yong V.W. and Antel J.P. (1992) Culture of glial cells form human brain biopsies. In: Protocols for Neural Cell Culture (Richardson A. and Fedoroff S., eds), pp. 81-96. Humana Press, St. Louis.