Oral administration of circulating precursors for membrane phosphatides can promote the synthesis of new brain synapses

Alzheimer's and Dementia

Volumn 4, Issue 1 SUPPL. 1, 2008, Pages

  Cansev, Mehmet ^a,b   Wurtman, Richard J ^a   Sakamoto, Toshimasa ^a   Ulus, Ismail H ^a,b  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b ULUDAG UNIVERSITY   (Turkey)

Author keywords

Alzheimer's disease; Dendritic spine; Docosahexaenoic acid; Phosphatide; Precursor; synaptic membrane; Uridine

Indexed keywords

ACETYLCHOLINE; ARACHIDONIC ACID; BETA TUBULIN; CHOLINE; CHOLINE KINASE; CHOLINE PHOSPHATE CYTIDYLYLTRANSFERASE; CHOLINEPHOSPHOTRANSFERASE; CYTIDINE DIPHOSPHATE; CYTIDINE TRIPHOSPHATE; DOCOSAHEXAENOIC ACID; DOPAMINE; GLUTAMATE RECEPTOR 1; ICOSAPENTAENOIC ACID; NEUROFILAMENT PROTEIN; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; OMEGA 3 FATTY ACID; PHOSPHOLIPID; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPSIN I; SYNTAXIN; SYNTAXIN 3; UNCLASSIFIED DRUG; URIDINE; URIDINE PHOSPHATE;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; ANIMAL BEHAVIOR; BEHAVIOR MODIFICATION; BRAIN CELL; BRAIN FUNCTION; BRAIN INJURY; DEGENERATIVE DISEASE; DENDRITIC SPINE; DIET SUPPLEMENTATION; DOPAMINE RELEASE; DRUG BIOAVAILABILITY; DRUG DOSE COMPARISON; DRUG METABOLISM; DRUG UPTAKE; EDITORIAL; GERBIL; HUMAN; MAMMAL CELL; NERVE CELL PLASTICITY; NEUROCHEMISTRY; NEUROTRANSMITTER RELEASE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STROKE; SYNAPSE; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS;

ADMINISTRATION, ORAL; ANIMALS; BRAIN; BRAIN DISEASES; CELL MEMBRANE; CHOLINE; DOCOSAHEXAENOIC ACIDS; HUMANS; MEMBRANE LIPIDS; PHOSPHOLIPIDS; PRODRUGS; SYNAPSES; SYNAPTIC TRANSMISSION; URIDINE;

EID: 38049116118     PISSN: 15525260     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jalz.2007.10.005     Document Type: Editorial

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