Inhibition of autophosphorylation of epidermal growth factor receptor by a small peptide not employing an ATP-competitive mechanism

Biopolymers

Volumn 89, Issue 1, 2008, Pages 40-51

  Abe, Mineo ^a   Kuroda, Yoshihiro ^a,d   Hirose, Munetaka ^b,e   Kato, Masaki ^a   Murakami, Masahiro ^c   Watanabe, Yoshihiko ^a   Nakano, Minoru ^a   Handa, Tetsurou ^a  

^a KYOTO UNIVERSITY   (Japan)

^b KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^c OSAKA OHTANI UNIVERSITY   (Japan)

^d HIMEJI DOKKYO UNIVERSITY   (Japan)

^e UNIVERSITY OF FUKUI   (Japan)

Author keywords

Anti cancer; Docking simulation; Epidermal growth factor receptor; Phosphorylation; Receptor tyrosine kinase

Indexed keywords

AUTOPHOSPHORYLATION SITES; EPIDERMAL GROWTH FACTOR RECEPTORS; INHIBITORY POTENCIES;

ADENOSINETRIPHOSPHATE; AMINO ACIDS; COMPUTER SIMULATION; ENZYME INHIBITION; GROWTH KINETICS; PHOSPHORYLATION; SUBSTITUTION REACTIONS;

PEPTIDES;

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ADENOSINE TRIPHOSPHATE; AMINO ACID DERIVATIVE; ASPARAGINYLTYROSYLGLUTAMINYLGLUTAMINYLASPARAGINE; ASPARTYLTYROSYLGLUTAMINYLGLUTAMINYLASPARTIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR; GLUTAMINYLASPARAGINYLALANYLGLUTAMINYLTYROSYLLEUCYLARGININE; GLUTAMYLASPARAGINYLALANYLGLUTAMYLTYROSYLLEUCYLARGININE; INSULIN RECEPTOR; UNCLASSIFIED DRUG; VALYLPROLYLGLUTAMYLTYROSYLISOLEUCYLASPARAGINYLGLUTAMINE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; DRUG INHIBITION; DRUG POTENCY; IN VITRO STUDY; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; HUMANS; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN KINASE INHIBITORS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, INSULIN;

EID: 38049103348     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20843     Document Type: Article

References (41)

1. Hunter, T. Philos Trans R Soc Lond B Biol Sci 1998, 353, 583-605.
2. Aaronson, S. A. Science 1991, 254, 1146-1153.
3. McInnes, C.; Sykes, B. D. Pept Sci 1997, 43, 339-366.
4. Lemmon, M. A.; Bu, Z.; Ladbury, J. E.; Zhou, M.; Pinchasi, D.; Lax, I.; Engelman, D. M.; Schlessinger, J. EMBO J 16: 281-294, 1997.
5. Jorissen, R. N.; Walker, F.; Pouliot, N.; Garrett, T. P. J.; Ward, C. W.; Burgess, W. Exp Cell Res 2003, 284, 31-53.
6. Lowenstein, E. J.; Daly, R. J.; Batzer, A. G.; Li, W.; Matgolis, B.; Lammers, R.; Ullich, A.; Skolnik, E. Y.; Bar-Sagi, D.; Schlessinger, J. Cell 1992, 70, 431-442.
7. Schlessinger, J. Cell 2000, 103, 211-225.
8. Hirose, M.; Kuroda, Y.; Sawa, S.; Nakagawa, T.; Hirata, M.; Sakaguchi, M.; Tanaka, Y. Br J Pharmacol 2004, 142, 222-228.
9. Abe, M.; Kuroda, Y.; Hirose, M.; Watanabe, Y.; Nakano, M.; Handa, T. Br J Pharmacol 2006, 147, 402-411.
10. Kemp, B. E.; Pearson, R. B.; House, C.; Robinson, P. J.; Means, A. R. Cell Signal 1989, 1, 303-311.
11. Hubbard, S. R.; Wei, L.; Ellis, L.; Hendrickson, W. A. Nature 1994, 372, 746-754.
12. Ablooglu, A. J.; Frankel, M.; Rusinova, E.; Ross, J. B. A.; Kohansli, R. A. J Biol Chem 2001, 276, 46933-46940.
13. Hubbard, S. R. EMBO J 1997, 16, 5572-5581.
14. Warren, G. L.; Andrews, C. W.; Capelli, A.-M.; Clarke, B.; LaLonde, J.; Lambert, M. H.; Lindvall, M.; Nevins, N.; Semus, S. F.; Senger, S.; Tadesco, G.; Wall, I. D.; Woolven, J. M.; Peishoff, C. E.; Head, M. S. J Med Chem 2006, 49, 5912-5931.
15. Berman, H. M.; Westbrook, J.; Feng, Z.; Gilliland, G.; Bhat, T. N.; Weissig, H.; Shindyalov, I. N.; Bourne, P. E. Nucleic Acids Res 2000, 28, 235-242.
16. Kuntz, I. D. Science 1992, 257, 1078-1082.
17. Kuntz, I. D.; Meng, E. C.; Shoichet, B. K. Acc Chem Res 1994, 27, 117-123.
18. Wakeling, A. E. Curr Opin Pharmacol 2002, 2, 382-387.
19. Stamos, J.; Sliwkowski, M. X.; Eigenbrot, C. J Biol Chem 2002, 277, 46265-46272.
20. Levitzki, A.; Gazit, A. Science 1995, 267, 1782-1788.
21. Osherov, N.; Gazit, A.; Gilon, C.; Levitzki, A. J Biol Chem 1993, 268, 11134-11142.
22. Niv, M. Y.; Rubin, H.; Cohen, J.; Tsirulnikov, L.; Licht, T.; Peretzman-Shemer, A.; Cna'an, E.; Tartakovsky, A.; Stein, I.; Albeck, S.; Weinstein, I.; Goldenberg-Furmanov, M.; Tobi, D.; Cohen, E.; Laster, M.; Ben-Sasson, S. A.; Reuveni, H. J Biol Chem 2004, 279, 1242-1255.
23. Mills, J. E. J.; Dean, P. M. J Comput Aided Mol Des 1996, 10, 607-622.
24. Ward, W. H. J.; Cook, P. N.; Slater, A. M.; Davies, D. H.; Holdgate, G. A.; Green, L. R. Biochem Pharmacol 1994, 48, 659-666.
25. Marshall, J. Cancer 2006, 107, 1207-1218.
26. Sequist, L. V. Oncologist 2007, 12, 325-330.
27. Rocha-Lima, C. M.; Soares, H. P.; Raez, L. E.; Singal, R. Cancer Control 2007, 14, 295-304.
28. Songyang, Z.; Carraway, K. L., III; Eck, M. J.; Harrison, S. C.; Feldman, R. A.; Mohammadi, M.; Schlessinger, J.; Hubbard, S. R.; Smith, D. P.; Eng, C.; Lorenzo, M. J.; Ponder, B. A. J.; Mayer, B. J.; Cantley, L. C. Nature 1995, 373, 536-539.
29. Vives, E.; Brodin, P.; Lebleu, B. J Biol Chem 1997, 272, 16010-16017.
30. Kelemen, B. R.; Hsiao, K.; Goueli, S. A. J Biol Chem 2002, 277, 8741-8748.
31. Levitzki, A. Acc Chem Res 2003, 36, 462-469.
32. Lawrence, D. S.; Niu, J. Pharmacol Ther 1998, 77, 81-114.
33. Traut, T. W. Mol Cell Biochem 1994, 140, 1-22.
34. DeLano, W. L. CCP4 Newsl Protein Crystallogr 2002, 40, 11.
35. Pettersen, E. F.; Goddard, T. D.; Huang, C. C.; Couch, G. S.; Greenblatt, D. M.; Meng, E. C.; Ferrin, T. E. J Comput Chem 2004, 25, 1605-1612.
36. Cornell, W. D.; Cieplak, P.; Bayly, C. I.; Gould, I. R.; Merz, K. M., Jr; Ferguson, D. M.; Spellmeyer, D. C.; Fox, T.; Caldwell, J. W.; Kollman, P. A. J Am Chem Soc 1995, 117, 5179-5197.
37. Shoichet, B. K.; Bodian, D. L.; Kuntz, I. D. J Comput Chem 1992, 13, 380-397.
38. Meng, E. C.; Shoichet, B. K.; Kuntz, I. D. J Comput Chem 1992, 13, 505-524.
39. Ewing, T. J. A.; Makino, S.; Skillman, A. G.; Kuntz, I. D. J Comput Aided Mol Des 2001, 15, 411-428.
40. Kollman, P. A.; Mossova, I.; Reyes, C.; Kuhn, B.; Huo, S.; Chong, L.; Lee, M.; Lee, T.; Duan, Y.; Wang, W.; Donini, O.; Srivasan, J.; Case, D. A.; Cheatam, T. E., III. Acc Chem Res 2000, 33, 889-897.
41. Onufriev, A.; Bashford, D.; Case, D. A. Proteins 2004, 55, 383-394.