Synthesis and testing of a triaza-cyclopenta[b]phenanthrene scaffold as a DNA binding agent

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 6, 2006, Pages 1902-1909

  Hooda, Jaipal ^a   Bednarski, David ^a   Irish, Lisa ^a   Firestine, Steven M ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

DNA binding agent; G quadruplex; Nucleic acid

Indexed keywords

8 METHYL 2 NITRO 7 OXO 8,11 DIHYDRO 7H 5,8,11 TRIAZA CYCLOPENTA[B]PHENANTHRENE 9 CARBOXYLIC ACID (2 DIMETHYLAMINO ETHYL) AMIDE; ANTINEOPLASTIC AGENT; ETHIDIUM BROMIDE; PHENANTHRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; AT RICH SEQUENCE; DNA SUPERCOILING; DRUG DESIGN; DRUG DNA BINDING; DRUG DNA INTERACTION; DRUG MECHANISM; DRUG SCREENING; DRUG SYNTHESIS; EQUILIBRIUM DIALYSIS; GC RICH SEQUENCE; MOLECULAR RECOGNITION;

BINDING, COMPETITIVE; DNA; MOLECULAR STRUCTURE; PHENANTHRENES;

EID: 32044449998     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.10.047     Document Type: Article

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