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Volumn 366, Issue 4, 2008, Pages 976-981

Inhibition of APP intracellular domain (AICD) transcriptional activity via covalent conjugation with Nedd8

Author keywords

AICD; APP; Nedd8; Protein modification; Transcriptional regulation; Ubiquitin like protein

Indexed keywords

AMINO ACID; AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN INTRACELLULAR DOMAIN; LYSINE; NEDD8 PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 37549028400     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.12.066     Document Type: Article
Times cited : (28)

References (27)
  • 2
    • 0035929554 scopus 로고    scopus 로고
    • Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch
    • Gu Y., Misonou H., Sato T., Dohmae N., Takio K., and Ihara Y. Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch. J. Biol. Chem. 276 (2001) 35235-35238
    • (2001) J. Biol. Chem. , vol.276 , pp. 35235-35238
    • Gu, Y.1    Misonou, H.2    Sato, T.3    Dohmae, N.4    Takio, K.5    Ihara, Y.6
  • 3
    • 18744405422 scopus 로고    scopus 로고
    • Cytoplasmic domain of the beta-amyloid protein precursor of Alzheimer's disease: function, regulation of proteolysis, and implications for drug development
    • Kerr M.L., and Small D.H. Cytoplasmic domain of the beta-amyloid protein precursor of Alzheimer's disease: function, regulation of proteolysis, and implications for drug development. J. Neurosci. Res. 80 (2005) 151-159
    • (2005) J. Neurosci. Res. , vol.80 , pp. 151-159
    • Kerr, M.L.1    Small, D.H.2
  • 4
    • 0035937153 scopus 로고    scopus 로고
    • The role of presenilins in gamma-secretase activity
    • Wolfe M.S., and Haass C. The role of presenilins in gamma-secretase activity. J. Biol. Chem. 276 (2001) 5413-5416
    • (2001) J. Biol. Chem. , vol.276 , pp. 5413-5416
    • Wolfe, M.S.1    Haass, C.2
  • 5
    • 0034604340 scopus 로고    scopus 로고
    • Alzheimer's disease: neurodevelopment converges with neurodegeneration
    • Bothwell M., and Giniger E. Alzheimer's disease: neurodevelopment converges with neurodegeneration. Cell 102 (2000) 271-273
    • (2000) Cell , vol.102 , pp. 271-273
    • Bothwell, M.1    Giniger, E.2
  • 6
    • 0033214675 scopus 로고    scopus 로고
    • Presenilins: molecular switches between proteolysis and signal transduction
    • Annaert W., and De Strooper B. Presenilins: molecular switches between proteolysis and signal transduction. Trends Neurosci. 22 (1999) 439-443
    • (1999) Trends Neurosci. , vol.22 , pp. 439-443
    • Annaert, W.1    De Strooper, B.2
  • 7
    • 0037118248 scopus 로고    scopus 로고
    • A RIP tide in neuronal signal transduction
    • Ebinu J.O., and Yankner B.A. A RIP tide in neuronal signal transduction. Neuron 34 (2002) 499-502
    • (2002) Neuron , vol.34 , pp. 499-502
    • Ebinu, J.O.1    Yankner, B.A.2
  • 8
    • 0037067655 scopus 로고    scopus 로고
    • Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein
    • Baek S.H., Ohgi K.A., Rose D.W., Koo E.H., Glass C.K., and Rosenfeld M.G. Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein. Cell 110 (2002) 55-67
    • (2002) Cell , vol.110 , pp. 55-67
    • Baek, S.H.1    Ohgi, K.A.2    Rose, D.W.3    Koo, E.H.4    Glass, C.K.5    Rosenfeld, M.G.6
  • 9
    • 33845324145 scopus 로고    scopus 로고
    • C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression
    • Kim H.S., Kim E.M., Lee J.P., Park C.H., Kim S., Seo J.H., Chang K.A., Yu E., Jeong S.J., Chong Y.H., and Suh Y.H. C-terminal fragments of amyloid precursor protein exert neurotoxicity by inducing glycogen synthase kinase-3beta expression. FASEB J. 17 (2003) 1951-1953
    • (2003) FASEB J. , vol.17 , pp. 1951-1953
    • Kim, H.S.1    Kim, E.M.2    Lee, J.P.3    Park, C.H.4    Kim, S.5    Seo, J.H.6    Chang, K.A.7    Yu, E.8    Jeong, S.J.9    Chong, Y.H.10    Suh, Y.H.11
  • 10
    • 5444275067 scopus 로고    scopus 로고
    • The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor
    • von Rotz R.C., Kohli B.M., Bosset J., Meier M., Suzuki T., Nitsch R.M., and Konietzko U. The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor. J. Cell Sci. 117 (2004) 4435-4448
    • (2004) J. Cell Sci. , vol.117 , pp. 4435-4448
    • von Rotz, R.C.1    Kohli, B.M.2    Bosset, J.3    Meier, M.4    Suzuki, T.5    Nitsch, R.M.6    Konietzko, U.7
  • 12
    • 0141426637 scopus 로고    scopus 로고
    • COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases
    • Cope G.A., and Deshaies R.J. COP9 signalosome: a multifunctional regulator of SCF and other cullin-based ubiquitin ligases. Cell 114 (2003) 663-671
    • (2003) Cell , vol.114 , pp. 663-671
    • Cope, G.A.1    Deshaies, R.J.2
  • 13
    • 0032053829 scopus 로고    scopus 로고
    • Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex
    • Lammer D., Mathias N., Laplaza J.M., Jiang W., Liu Y., Callis J., Goebl M., and Estelle M. Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev. 12 (1998) 914-926
    • (1998) Genes Dev. , vol.12 , pp. 914-926
    • Lammer, D.1    Mathias, N.2    Laplaza, J.M.3    Jiang, W.4    Liu, Y.5    Callis, J.6    Goebl, M.7    Estelle, M.8
  • 14
    • 0032522382 scopus 로고    scopus 로고
    • A novel protein modification pathway related to the ubiquitin system
    • Liakopoulos D., Doenges G., Matuschewski K., and Jentsch S. A novel protein modification pathway related to the ubiquitin system. EMBO J. 17 (1998) 2208-2214
    • (1998) EMBO J. , vol.17 , pp. 2208-2214
    • Liakopoulos, D.1    Doenges, G.2    Matuschewski, K.3    Jentsch, S.4
  • 17
    • 3142570737 scopus 로고    scopus 로고
    • Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity
    • Xirodimas D.P., Saville M.K., Bourdon J.C., Hay R.T., and Lane D.P. Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity. Cell 118 (2004) 83-97
    • (2004) Cell , vol.118 , pp. 83-97
    • Xirodimas, D.P.1    Saville, M.K.2    Bourdon, J.C.3    Hay, R.T.4    Lane, D.P.5
  • 19
    • 0035816661 scopus 로고    scopus 로고
    • A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X., and Sudhof T.C. A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293 (2001) 115-120
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 22
    • 20444422945 scopus 로고    scopus 로고
    • Differential interactions of the homeodomain-interacting protein kinase 2 (HIPK2) by phosphorylation-dependent sumoylation
    • Sung K.S., Go Y.Y., Ahn J.H., Kim Y.H., Kim Y., and Choi C.Y. Differential interactions of the homeodomain-interacting protein kinase 2 (HIPK2) by phosphorylation-dependent sumoylation. FEBS Lett. 579 (2005) 3001-3008
    • (2005) FEBS Lett. , vol.579 , pp. 3001-3008
    • Sung, K.S.1    Go, Y.Y.2    Ahn, J.H.3    Kim, Y.H.4    Kim, Y.5    Choi, C.Y.6
  • 24
    • 34249704660 scopus 로고    scopus 로고
    • Modulation of Abeta generation by small ubiquitin-like modifiers does not require conjugation to target proteins
    • Dorval V., Mazzella M.J., Mathews P.M., Hay R.T., and Fraser P.E. Modulation of Abeta generation by small ubiquitin-like modifiers does not require conjugation to target proteins. Biochem. J. 404 (2007) 309-316
    • (2007) Biochem. J. , vol.404 , pp. 309-316
    • Dorval, V.1    Mazzella, M.J.2    Mathews, P.M.3    Hay, R.T.4    Fraser, P.E.5
  • 26
    • 33749173298 scopus 로고    scopus 로고
    • Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkappaB-dependent transcription
    • Gao F., Cheng J., Shi T., and Yeh E.T. Neddylation of a breast cancer-associated protein recruits a class III histone deacetylase that represses NFkappaB-dependent transcription. Nat. Cell Biol. 8 (2006) 1171-1177
    • (2006) Nat. Cell Biol. , vol.8 , pp. 1171-1177
    • Gao, F.1    Cheng, J.2    Shi, T.3    Yeh, E.T.4
  • 27
    • 0037827785 scopus 로고    scopus 로고
    • X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence
    • King G.D., Perez R.G., Steinhilb M.L., Gaut J.R., and Turner R.S. X11alpha modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the YENPTY sequence. Neuroscience 120 (2003) 143-154
    • (2003) Neuroscience , vol.120 , pp. 143-154
    • King, G.D.1    Perez, R.G.2    Steinhilb, M.L.3    Gaut, J.R.4    Turner, R.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.