Crystal structure of the interleukin-15·interleukin-15 receptor α complex: Insights into trans and cis presentation

Journal of Biological Chemistry

Volumn 282, Issue 51, 2007, Pages 37191-37204

  Olsen, Shaun K ^a   Ota, Naruhisa ^b   Kishishita, Seiichiro ^a   Kukimoto Niino, Mutsuko ^a   Murayama, Kazutaka ^a,c   Uchiyama, Hidemi ^b   Toyama, Mitsutoshi ^a   Terada, Takaho ^a   Shirouzu, Mikako ^a   Kanagawa, Osami ^b   Yokoyama, Shigeyuki ^a,d  

^a RIKEN YOKOHAMA INSTITUTE   (Japan)

^b RIKEN Center for Integrative Medical Sciences   (Japan)

^c TOHOKU UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL CULTURE; CRYSTAL STRUCTURE; LIGANDS; MOLECULAR MODELING;

PLEIOTROPIC CYTOKINE; TRANS SIGNALING MECHANISM;

POLYPEPTIDES;

EPITOPE; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR ALPHA; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 2 RECEPTOR GAMMA;

ADAPTIVE IMMUNITY; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CIS TRANS ISOMERISM; CONFORMATION; CRYSTAL STRUCTURE; INNATE IMMUNITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION;

ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; EPITOPES; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-15; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; MICE; MODELS, MOLECULAR; MULTIPROTEIN COMPLEXES; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, INTERLEUKIN-15; SIGNAL TRANSDUCTION;

EID: 37549007225     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M706150200     Document Type: Article

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