Soluble interleukin-15 receptor α (IL-15Rα)-sushi as a selective and potent agonist of IL-15 action through IL-15Rβ/γ: Hyperagonist IL-15·IL-15Rα fusion proteins

Journal of Biological Chemistry

Volumn 281, Issue 3, 2006, Pages 1612-1619

  Mortier, Erwan ^a,b   Quéméner, Agnès ^a,b   Vusio, Patricia ^b   Lorenzen, Inken ^c   Boublik, Yvan ^d   Grötzinger, Joachim ^c   Plet, Ariane ^a,b   Jacques, Yannick ^a,b  

^a INSTITUT DE BIOLOGIE   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c UNIVERSITY OF KIEL   (Germany)

^d Centre National de la Recherche Scientifique   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER;

GAJENDRA;

GALLIUM;

CYTOKINE RECEPTOR AGONIST; HYBRID PROTEIN; INTERLEUKIN 15; INTERLEUKIN 15 RECEPTOR BETA; INTERLEUKIN 15 RECEPTOR GAMMA; INTERLEUKIN RECEPTOR; SOLUBLE INTERLEUKIN 15 RECEPTOR ALPHA; UNCLASSIFIED DRUG; IL15RA PROTEIN, HUMAN; IL2RB PROTEIN, HUMAN; IL2RG PROTEIN, HUMAN; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 2 RECEPTOR GAMMA;

APOPTOSIS; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CELL PROTECTION; CONTROLLED STUDY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; CHO CELL; DIMERIZATION; DRUG POTENTIATION; ERYTHROLEUKEMIA; GENETIC TRANSFECTION; HAMSTER; KINETICS; METABOLISM; PHYSIOLOGY; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHO CELLS; CRICETINAE; DIMERIZATION; HUMANS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-15; INTERLEUKIN-2 RECEPTOR BETA SUBUNIT; KINETICS; LEUKEMIA, ERYTHROBLASTIC, ACUTE; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-2; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 33644975335     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508624200     Document Type: Article

References (41)

1. Grabstein, K. H., Eisenman, J., Shanebeck, K., Rauch, C., Srinivasan, S., Fung, V., Beers, C., Richardson, J., Schoenborn, M. A., Ahdieh, M., Johnson, L., Alderson, M. R., Watson, J. D., Anderson, D. M., and Giri, J. G. (1994) Science 264, 965-968
2. Giri, J. G., Ahdieh, M., Eisenman, J., Shanebeck, K., Grabstein, K., Kumaki, S., Namen, A., Park, L. S., Cosman, D., and Anderson, D. (1994) EMBO J. 13, 2822-2830
3. Anderson, D. M., Kumaki, S., Ahdieh, M., Bertles, J., Tometsko, M., Loomis, A., Giri, J., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Valentine, V., Shapiro, D. N., Morris, S. W., Park, L. S., and Cosman, D. (1995) J. Biol. Chem. 270, 29862-29869
4. Burton, J. D., Bamford, R. N., Peters, C., Grant, A. J., Kurys, G., Goldman, C. K., Brennan, J., Roessler, E., and Waldmann, T. A. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 4935-4939
5. Carson, W. E., Giri, J. G., Lindemann, M. J., Linett, M. L., Ahdieh, M., Paxton, R., Anderson, D., Eisenmann, J., Grabstein, K., and Caligiuri, M. A. (1994) J. Exp. Med. 180, 1395-1403
6. Wilkinson, P. C., and Liew, F. Y. (1995) J. Exp. Med. 181, 1255-1259
7. Kennedy, M. K., Glaccum, M., Brown, S. N., Butz, E. A., Viney, J. L., Embers, M., Matsuki, N., Charrier, K., Sedger, L., Willis, C. R., Brasel, K., Morrissey, P. J., Stocking, K., Schuh, J. C., Joyce, S., and Peschon, J. J. (2000) J. Exp. Med. 191, 771-780
8. Lodolce, J. P., Burkett, P. R., Boone, D. L., Chien, M., and Ma, A. (2001) J. Exp. Med. 194, 1187-1194
9. Marks-Konczalik, J., Dubois, S., Losi, J. M., Sabzevari, H., Yamada, N., Feigenbaum, L., Waldmann, T. A., and Tagaya, Y. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 11445-11450
10. Ku, C. C., Murakami, M., Sakamoto, A., Kappler, J., and Marrack, P. (2000) Science 288, 675-678
11. Li, X. C., Demirci, G., Ferrari-Lacraz, S., Groves, C., Coyle, A., Malek, T. R., and Strom, T. B. (2001) Nat. Med. 7, 114-118
12. Dubois, S., Mariner, J., Waldmann, T. A., and Tagaya, Y. (2002) Immunity 17, 537-547
13. Burkett, P. R., Koka, R., Chien, M., Chai, S., Chan, F., Ma, A., and Boone, D. L. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 4724-4729
14. Schluns, K. S., Nowak, E. C., Cabrera-Hernandez, A., Puddington, L., Lefrancois, L., and Aguila, H. L. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 5616-5621
15. Kobayashi, H., Dubois, S., Sato, N., Sabzevari, H., Sakai, Y., Waldmann, T. A., and Tagaya, Y. (2005) Blood 105, 721-727
16. Norman, D. G., Barlow, P. N., Baron, M., Day, A. J., Sim, R. B., and Campbell, I. D. (1991) J. Mol. Biol. 219, 717-725
17. Schulz, O., Sewell, H. F., and Shakib, F. (1998) J. Exp. Med. 187, 271-275
18. Sheu, B. C., Hsu, S. M., Ho, H. N., Lien, H. C., Huang, S. C., and Lin, R. H. (2001) Cancer Res. 61, 237-242
19. Mortier, E., Bernard, J., Plet, A., and Jacques, Y. (2004) J. Immunol. 173, 1681-1688
20. Ruchatz, H., Leung, B. P., Wei, X. Q., McInnes, I. B., and Liew, F. Y. (1998) J. Immunol. 160, 5654-5660
21. Smith, X. G., Bolton, E. M., Ruchatz, H., Wei, X., Liew, F. Y., and Bradley, J. A. (2000) J. Immunol. 165, 3444-3450
22. Meazza, R., Basso, S., Gaggero, A., Detotero, D., Trentin, L., Pereno, R., Azzarone, B., and Ferrini, S. (1998) Int. J. Cancer 78, 189-195
23. Farner, N. L., Gan, J., de Jong, J. L., Leary, T. P., Fenske, T. S., Buckley, P., Dunlap, S., and Sondel, P. M. (1997) Cytokine 9, 316-327
24. Hori, T., Uchiyama, T., Tsudo, M., Umadome, H., Ohno, H., Fukuhara, S., Kita, K., and Uchino, H. (1987) Blood 70, 1069-1072
25. Nakamura, Y., Russell, S. M., Mess, S. A., Friedmann, M., Erdos, M., Francois, C., Jacques, Y., Adelstein, S., and Leonard, W. J. (1994) Nature 369, 330-333
26. Bernard, J., Harb, C., Mortier, E., Quemener, A., Meloen, R. H., Vermot-Desroches, C., Wijdeness, J., van Dijken, P., Grotzinger, J., Slootstra, J. W., Plet, A., and Jacques, Y. (2004) J. Biol. Chem. 279, 24313-24322
27. Matsumoto, M., Misawa, S., Tsumoto, K., Kumagai, I., Hayashi, H., and Kobayashi, Y. (2003) Protein Expr. Purif. 31, 64-71
28. Dubois, S., Magrangeas, F., Lehours, P., Raher, S., Bernard, J., Boisteau, O., Leroy, S., Minvielle, S., Godard, A., and Jacques, Y. (1999) J. Biol. Chem. 274, 26978-26984
29. Giron-Michel, J., Giuliani, M., Fogli, M., Brouty-Boye, D., Ferrini, S., Baychelier, F., Eid, P., Lebousse-Kerdiles, C., Durali, D., Biassoni, R., Charpentier, B., Vasquez, A., Chouaib, S., Caignard, A., Moretta, L., and Azzarone, B. (2005) Blood 106, 2302-2310
30. Meissner, U., Blum, H., Schnare, M., Rollinghoff, M., and Gessner, A. (2001) Blood 97, 183-191
31. Jones, S. A., and Rose-John, S. (2002) Biochim. Biophys. Acta 1592, 251-263
32. Heaney, M. L., and Golde, D. W. (1998) J. Leukoc. Biol. 64, 135-146
33. Rose-John, S., and Heinrich, P. C. (1994) Biochem. J. 300, 281-290
34. Pflanz, S., Tacken, I., Grotzinger, J., Jacques, Y., Minvielle, S., Dahmen, H., Heinrich, P. C., and Muller-Newen, G. (1999) FEBS Lett. 450, 117-122
35. Davis, S., Aldrich, T. H., Ip, N. Y., Stahl, N., Scherer, S., Farruggella, T., DiStefano, P. S., Curtis, R., Panayotatos, N., Gascan, H., Chevalier, S., and Yancopoulas, G. D. (1993) Science 259, 1736-1739
36. Karow, J., Hudson, K. R., Hall, M. A., Vernallis, A. B., Taylor, J. A., Gossler, A., and Heath, J. K. (1996) Biochem. J. 318, 489-495
37. Elson, G. C., Lelievre, E., Guillet, C., Chevalier, S., Plun-Favreau, H., Froger, J., Suard, I., de Coignac, A. B., Delneste, Y., Bonnefoy, J. Y., Gauchat, J. F., and Gascan, H. (2000) Nat. Neurosci. 3, 867-872
38. Sandau, M. M., Schluns, K. S., Lefrancois, L., and Jameson, S. C. (2004) J. Immunol. 173, 6537-6541
39. Koka, R., Burkett, P. R., Chien, M., Chai, S., Chan, F., Lodolce, J. P., Boone, D. L., and Ma, A. (2003) J. Exp. Med. 197, 977-984
40. Bulanova, E., Budagian, V., Orinska, Z., Krause, H., Paus, R., and Bulfone-Paus, S. (2003) J. Immunol. 170, 5045-5055
41. Fischer, M., Goldschmitt, J., Peschel, C., Brakenhoff, J. P., Kallen, K. J., Wollmer, A., Grotzinger, J., and Rose-John, S. (1997) Nat. Biotechnol. 15, 142-145