Active components and clinical applications of olive oil

Alternative Medicine Review

Volumn 12, Issue 4, 2007, Pages 331-342

  Waterman, Emily ^c   Lockwood, Brian ^a,b  

^a School of Pharmacy and Pharmaceutical Sciences

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c Leeds General Hospital   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYTYROSOL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MONOUNSATURATED FATTY ACID; OLEIC ACID; OLEUROPEIN; OLIVE OIL; PHENOL DERIVATIVE; SQUALENE; TRASTUZUMAB; TYROSOL;

ANTIBACTERIAL ACTIVITY; ANTIOXIDANT ACTIVITY; COOKING; DIETARY INTAKE; DISEASE MODEL; DRUG EFFECT; DRUG STRUCTURE; HUMAN; ISCHEMIC HEART DISEASE; LIPID PEROXIDATION; MEDITERRANEAN DIET; NONHUMAN; OLIVE TREE; REVIEW; RISK REDUCTION;

ANTI-BACTERIAL AGENTS; ARTHRITIS, RHEUMATOID; COOKERY; CORONARY DISEASE; HYPERTENSION; NEOPLASMS; OLEIC ACID; PHENOLS; PLANT OILS; SQUALENE;

EID: 37549003700     PISSN: 10895159     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (53)

1. Gilani AH, Khan AU, Shah AJ, et al. Blood pressure lowering effect of olive is mediated through calcium channel blockade. Int J Food Sci Nutr 2005;56:613-620.
2. Wahrburg U, Kratz M, Cullen P. Mediterranean diet, olive oil and health. Eur J Lipid Sci Technol 2002;104:698-705.
3. Visioli F, Poli A, Gall C. Antioxidant and other biological activities of phenols from olives and olive oil. Med Res Rev 2002;22:65-75.
4. Harwood JL, Yaqoob P. Nutritional and health aspects of olive oil. Eur J Lipid Sci Technol 2002;104:685-697.
5. Keys A, Menotti A, Karvonen MJ, et al. The diet and 15-year death rate in the Seven Countries Study. Am J Epidemiol 1986;124:903-915.
6. Owen RW, Haubner R, Wurtele G, et al. Olives and olive oil in cancer prevention. Eur J Cancer Prev 2004;13:319-326.
7. Owen RW, Giacosa A, Hull WE, et al. Olive-oil consumption and health: the possible role of antioxidants. Lancet Oncol 2000;1:107-112.
8. Visioli F, Galli C, Galli G, Caruso D. Biological activities and metabolic fate of olive oil phenols. Eur J Lipid Sci Technol 2002;104:677-684.
9. Newmark HL. Squalene, olive oil, and cancer risk: a review and hypothesis. Cancer Epidemiol Biomarkers Prev 1997;6:1101-1103.
10. Owen RW, Mier W, Giacosa A, et al. Phenolic compounds and squalene in olive oils: the concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene. Food Chem Toxicol 2000;38:647-659.
11. Menendez JA, Vellon L, Colomer R, Lupu R. Oleic acid, the main monounsaturated fatty acid of olive oil, suppresses Her-2/neu (erbB-2) expression and synergistically enhances the growth inhibitory effects of trastuzumab (Herceptin) in breast cancer cells with Her-2/neu oncogene amplification. Ann Oncol 2005;16:359-371.
12. Visioli F, Grande S, Bogani P, Galli C. The role of antioxidants in the Mediterranean diets: focus on cancer. Eur J Cancer Prev 2004;13:337-343.
13. Llor X, Pons E, Roca A, et al. The effects of fish oil, olive oil, oleic acid and linoleic acid on colorectal neoplastic processes. Clin Nutr 2003;22:71-79.
14. Menendez JA, Papadimitropoulou A, Vellon L, Lupu R. A genomic explanation connecting "Mediterranean diet," olive oil and cancer: oleic acid, the main monounsaturated fatty acid of olive oil, induces formation of inhibitory "PEA3 transcription factor-PEA3 DNA binding site" complexes at the Her-2/ neu (erbB-2) oncogene promoter in breast, ovarian and stomach cancer cells. Eur J Cancer 2006;42:2425-2432.
15. Tuck KL, Hayball PJ. Major phenolic compounds in olive oil: metabolism and health effects. J Nutr Biochem 2002;13:636-644.
16. Perona JS, Cabello-Moruno R, Ruiz-Gutierrez V. The role of virgin olive oil components in the modulation of endothelial function. J Nutr Biochem 2006;17:429-445.
17. Romero C, Medina E, Vargas J, et al. In vitro activity of olive oil polyphenols against Helicobacter pylori. J Agric Food Chem 2007;55:680-686.
18. Martinez-Dominguez E, De la Puerta R, Ruiz-Gutierrez V. Protective effects upon experimental inflammation models of a polyphenol-supplemented virgin olive oil diet. Inflamm Res 2001;50:102-106.
19. Fabiani R, De Bartolomeo A, Rosignoli P, et al. Cancer chemoprevention by hydroxytyrosol isolated from virgin olive oil through G1 cell cycle arrest and apoptosis. Eur J Cancer Prev 2002;11:351-358.
20. Beauchamp GK, Keast RS, Morel D, et al. Phytochemistry: Ibuprofen-like activity in extra-virgin olive oil. Nature 2005;437:45-46.
21. Relas H, Gylling H, Miettinen TA. Dietary squalene increases cholesterol synthesis measured with serum non-cholesterol sterols after a single oral dose in humans. Atherosclerosis 2000;152:377-383.
22. Strandberg TE, Tilvis RS, Miettinen TA. Metabolic variables of cholesterol during squalene feeding in humans: comparison with cholestyramine treatment. J Lipid Res 1990;31:1637-1643.
23. Brenes M, Garcia A, Dobarganes MC, et al. Influence of thermal treatments simulating cooking processes on the polyphenol content in virgin olive oil. J Agric Food Chem 2002;50:5962-5967.
24. Caponio F, Pasqualone A, Gomes T. Effects of conventional and microwave heating on the degradation of olive oil. Eur Food Res Technol 2002;215:114-117.
25. Gennaro L, Bocca AP, Modesti D, et al. Effect of biophenols on olive oil stability evaluated by thermogravimetric analysis. J Agric Food Chem 1998;6:4465-4469.
26. Quiles JL, Ramirez-Tortosa MC, Gomez JA, et al. Role of vitamin E and phenolic compounds in the antioxidant capacity, measured by ESR, of virgin olive, olive and sunflower oils after frying. Food Chem 2002;76:461-468.
27. Galeone C, Talamini R, Levi F, et al. Fried foods, olive oil and colorectal cancer. Ann Oncol 2007;18:36-39.
28. Bastida S, Sanchez-Muniz FJ. Thermal oxidation of olive oil, sunflower oil and a mix of both oils during forty discontinuous domestic fryings of different foods. Food Sci Technol Int 2001;7:15-21.
29. Monti SM, Ritieni A, Sacchi R, et al. Characterization of phenolic compounds in virgin olive oil and their effect on the formation of carcinogenic/mutagenic heterocyclic amines in a model system. J Agric Food Chem 2001;49:3969-3975.
30. de Lorgeril M, Salen P. The Mediterranean diet in secondary prevention of coronary heart disease. Clin Invest Med 2006;29:154-158.
31. de Lorgeril M, Salen P. The Mediterranean-style diet for the prevention of cardiovascular diseases. Public Health Nutr 2006;9:118-123.
32. Patrick L, Uzick M. Cardiovascular disease: C-reactive protein and the inflammatory disease paradigm: HMG-CoA reductase inhibitors, alpha-tocopherol, red yeast rice, and olive oil polyphenols. A review of the literature. Altern Med Rev 2001;6:248-271.
33. Salami M, Galli C, De Angelis L, Visioli F. Formation of F2-isoprostanes in oxidized low density lipoprotein: inhibitory effect of hydroxytyrosol. Pharmacol Res 1995;31:275-279.
34. Carollo C, Presti RL, Caimi G. Wine, diet, and arterial hypertension. Angiology 2007;58:92-96.
35. Psaltopoulou T, Naska A, Orfanos P, et al. Olive oil, the Mediterranean diet, and arterial blood pressure: the Greek European Prospective Investigation into Cancer and Nutrition (EPIC) study. Am J Clin Nutr 2004;80:1012-1018.
36. Ruiz-Gutierrez V, Muriana FJ, Guerrero A, et al. Role of dietary oleic acid from different sources on fatty acid composition of erythrocyte membrane and blood pressure in healthy subjects. J Nutr Biochem 1997;8:689-695.
37. Alonso A, Ruiz-Gutierrez V, Martinez-Gonzalez MA. Monounsaturated fatty acids, olive oil and blood pressure: epidemiological, clinical and experimental evidence. Public Health Nutr 2006;9:251-257.
38. Ferrara LA, Raimondi AS, d'Episcopo L, et al. Olive oil and reduced need for antihypertensive medications. Arch Intern Med 2000;160:837-842.
39. Herrera MD, Perez-Guerrero C, Marhuenda E, Ruiz-Gutierrez V. Effects of dietary oleic-rich oils (virgin olive and high-oleic-acid sunflower) on vascular reactivity in Wistar-Kyoto and spontaneously hypertensive rats. Br J Nutr 2001;86:349-357.
40. Hamdi HK, Castellon R. Oleuropein, a non-toxic olive iridoid, is an anti-tumor agent and cytoskeleton disruptor. Biochem Biophys Res Commun 2005;334:769-778.
41. Simonsen NR, Fernandez-Crehuet Navajas J, Martin-Moreno JM, et al. Tissue stores of individual monounsaturated fatty acids and breast cancer: the EURAMIC study. European Community Multicenter Study on Antioxidants, Myocardial Infarction, and Breast Cancer. Am J Clin Nutr 1998;68:134-141.
42. Gill CI, Boyd A, McDermott E, et al. Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro. Int J Cancer 2005;117:1-7.
43. Sieri S, Krogh V, Pala V, et al. Dietary patterns and risk of breast cancer in the ORDET cohort. Cancer Epidemiol Biomarkers Prev 2004;13:567-572.
44. Masala G, Ambrogetti D, Assedi M, et al. Dietary and lifestyle determinants of mammographic breast density. A longitudinal study in a Mediterranean population. Int J Cancer 2006;118:1782-1789.
45. Solanas M, Hurtado A, Costa I, et al. Effects of a high olive oil diet on the clinical behavior and histopathological features of rat DMBA-induced mammary tumors compared with a high corn oil diet. Int J Oncol 2002;21:745-753.
46. Costa I, Moral R, Solanas M, Escrich E. High-fat corn oil diet promotes the development of high histologic grade rat DMBA-induced mammary adenocarcinomas, while high olive oil diet does not. Breast Cancer Res Treat 2004;86:225-235.
47. Darlington LG, Stone TW. Antioxidants and fatty acids in the amelioration of rheumatoid arthritis and related disorders. Br J Nutr 2001;85:251-269.
48. Soeken KL, Miller SA, Ernst E. Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. Rheumatology (Oxford) 2003;42:652-659.
49. Jantti J, Seppala E, Vapaatalo H, Isomaki H. Evening primrose oil and olive oil in treatment of rheumatoid arthritis. Clin Rheumatol 1989;8:238-244.
50. Kremer JM, Lawrence DA, Jubiz W et al. Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects. Arthritis Rheum 1990;33:810-820.
51. Berbert AA, Kondo CR, Almendra CL, et al. Supplementation of fish oil and olive oil in patients with rheumatoid arthritis. Nutrition 2005;21:131-136.
52. Linos A, Kaklamani VG, Kaklamani E, et al. Dietary factors in relation to rheumatoid arthritis: a role for olive oil and cooked vegetables? Am J Clin Nutr 1999;70:1077-1082.
53. Vissers MN, Zock PL, Roodenburg AJ, et al. Olive oil phenols are absorbed in humans. J Nutr 2002;132:409-417.