-
1
-
-
34247481344
-
Mast cells-key effector cells in immune responses
-
Metz, M. & Maurer, M. Mast cells-key effector cells in immune responses. Trends Immunol. 28, 234-241 (2007).
-
(2007)
Trends Immunol
, vol.28
, pp. 234-241
-
-
Metz, M.1
Maurer, M.2
-
2
-
-
0024449425
-
Complete structure of the mouse mast cell receptor for IgE (Fc6RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells
-
Ra, C., Jouvin, M.H. & Kinet, J.P. Complete structure of the mouse mast cell receptor for IgE (Fc6RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells. J. Biol. Chem. 264, 15323-15327 (1989).
-
(1989)
J. Biol. Chem
, vol.264
, pp. 15323-15327
-
-
Ra, C.1
Jouvin, M.H.2
Kinet, J.P.3
-
3
-
-
0036195935
-
Selective loss of gastrointestinal mast cells and impaired immunity in P13K-deficient mice
-
Fukao, T. et al. Selective loss of gastrointestinal mast cells and impaired immunity in P13K-deficient mice. Nat Immunol. 3, 295-304 (2002).
-
(2002)
Nat Immunol
, vol.3
, pp. 295-304
-
-
Fukao, T.1
-
4
-
-
7244232917
-
Essential role for the p110δ phosphoinositide 3-kinase in the allergic response
-
Ali, K. et al. Essential role for the p110δ phosphoinositide 3-kinase in the allergic response. Nature 431, 1007-1011 (2004).
-
(2004)
Nature
, vol.431
, pp. 1007-1011
-
-
Ali, K.1
-
5
-
-
33344470236
-
Integrated signalling pathways for mast-cell activation
-
Gilfillan, A.M. & Tkaczyk, C. Integrated signalling pathways for mast-cell activation. Nat. Rev. Immunol. 6, 218-230 (2006).
-
(2006)
Nat. Rev. Immunol
, vol.6
, pp. 218-230
-
-
Gilfillan, A.M.1
Tkaczyk, C.2
-
6
-
-
0037108376
-
Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production
-
Nguyen, M. et al. Receptors and signaling mechanisms required for prostaglandin E2-mediated regulation of mast cell degranulation and IL-6 production. J. Immunol. 169, 4586-4593 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 4586-4593
-
-
Nguyen, M.1
-
7
-
-
0038205888
-
Activation of murine lung mast cells by the adenosine A3 receptor
-
Zhong, H. et al. Activation of murine lung mast cells by the adenosine A3 receptor. J. Immunol. 171, 338-345 (2003).
-
(2003)
J. Immunol
, vol.171
, pp. 338-345
-
-
Zhong, H.1
-
8
-
-
12544256541
-
Sphingolipids and the balancing of immune cell function: Lessons from the mast cell
-
Olivera, A. & Rivera, J. Sphingolipids and the balancing of immune cell function: Lessons from the mast cell. J. Immunol. 174, 1153-1158 (2005).
-
(2005)
J. Immunol
, vol.174
, pp. 1153-1158
-
-
Olivera, A.1
Rivera, J.2
-
9
-
-
1842682019
-
Transactivation of sphingosine-1-phosphate receptors by FcεRI triggering is required for normal mast cell degranulation and chemotaxis
-
Jolly, P.S. et al. Transactivation of sphingosine-1-phosphate receptors by FcεRI triggering is required for normal mast cell degranulation and chemotaxis. J. Exp Med. 199, 959-970 (2004).
-
(2004)
J. Exp Med
, vol.199
, pp. 959-970
-
-
Jolly, P.S.1
-
10
-
-
0023062991
-
G proteins: Transducers of receptor-generated signals
-
Gilman, A.G. G proteins: Transducers of receptor-generated signals. Annu. Rev. Biochem. 56, 615-649 (1987).
-
(1987)
Annu. Rev. Biochem
, vol.56
, pp. 615-649
-
-
Gilman, A.G.1
-
11
-
-
33746012348
-
Mammalian RGS proteins: Multifunctional regulators of cellular signalling
-
Willars, G.B. Mammalian RGS proteins: Multifunctional regulators of cellular signalling. Semin. Cell Dev. Biol. 17, 363-376 (2006).
-
(2006)
Semin. Cell Dev. Biol
, vol.17
, pp. 363-376
-
-
Willars, G.B.1
-
12
-
-
0035900060
-
-
Druey, K.M. Bridging with GAPs: Receptor communication through RGS proteins. Sci. STKE[online] 104, RE14 (2001)(doi:10.1126/ stke.2001.1104.re1114).
-
Druey, K.M. Bridging with GAPs: Receptor communication through RGS proteins. Sci. STKE[online] 104, RE14 (2001)(doi:10.1126/ stke.2001.1104.re1114).
-
-
-
-
13
-
-
29144496947
-
Increased expression of genes linked to FcsRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells
-
Hernandez-Hansen, V. et al. Increased expression of genes linked to FcsRI Signaling and to cytokine and chemokine production in Lyn-deficient mast cells. J. Immunol. 175, 7880-7888 (2005).
-
(2005)
J. Immunol
, vol.175
, pp. 7880-7888
-
-
Hernandez-Hansen, V.1
-
14
-
-
0037340794
-
Striatal gene expression of RGS2 and RGS4 is specifically mediated by dopamine D1 and D2 receptors: Clues for RGS2 and RGS4 functions
-
Taymans, J.M., Leysen, J.E. & Langlois, X. Striatal gene expression of RGS2 and RGS4 is specifically mediated by dopamine D1 and D2 receptors: clues for RGS2 and RGS4 functions. J. Neurochem. 84, 1118-1127 (2003).
-
(2003)
J. Neurochem
, vol.84
, pp. 1118-1127
-
-
Taymans, J.M.1
Leysen, J.E.2
Langlois, X.3
-
15
-
-
0036200415
-
Phosphoinositide 3-kinase γ is an essential amplifier of mast cell function
-
Laffargue, M. et al. Phosphoinositide 3-kinase γ is an essential amplifier of mast cell function. Immunity 16, 441-451 (2002).
-
(2002)
Immunity
, vol.16
, pp. 441-451
-
-
Laffargue, M.1
-
16
-
-
0031474423
-
RGS2/G058 is a selective inhibitor of Gqα function
-
Heximer, S.P., Watson, N., Linder, M.E., Blumer, K.J. & Hepler, J.R. RGS2/G058 is a selective inhibitor of Gqα function. Proc. Natl. Acad. Sci. USA 94, 14389-14393 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14389-14393
-
-
Heximer, S.P.1
Watson, N.2
Linder, M.E.3
Blumer, K.J.4
Hepler, J.R.5
-
17
-
-
0141483031
-
Role of phosphoinositide 3-kinase signaling in mast cells; new insights from knockout mouse studies
-
Fukao, T., Terauchi, Y., Kadowaki, T. & Koyasu, S. Role of phosphoinositide 3-kinase signaling in mast cells; new insights from knockout mouse studies. J. Mol. Med. 81, 524-535 (2003).
-
(2003)
J. Mol. Med
, vol.81
, pp. 524-535
-
-
Fukao, T.1
Terauchi, Y.2
Kadowaki, T.3
Koyasu, S.4
-
18
-
-
32044474897
-
Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcεRI
-
Yu, M., Lowell, C.A., Neel, B.G. & Gu, H. Scaffolding adapter Grb2-associated binder 2 requires Syk to transmit signals from FcεRI. J. Immunol. 176, 2421-2429 (2006).
-
(2006)
J. Immunol
, vol.176
, pp. 2421-2429
-
-
Yu, M.1
Lowell, C.A.2
Neel, B.G.3
Gu, H.4
-
19
-
-
0035849822
-
Essential role for Gab2 in the allergic response
-
Gu, H. et al. Essential role for Gab2 in the allergic response. Nature 412, 186-190 (2001).
-
(2001)
Nature
, vol.412
, pp. 186-190
-
-
Gu, H.1
-
20
-
-
0026593547
-
Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling
-
Yamanashi, Y. et al. Activation of Src-like protein-tyrosine kinase Lyn and its association with phosphatidylinositol 3-kinase upon B-cell antigen receptor-mediated signaling. Proc. Natl. Acad. Sci. USA 89, 1118-1122 (1992).
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 1118-1122
-
-
Yamanashi, Y.1
-
21
-
-
0035920129
-
Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase
-
Cuevas, B.D. et al. Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase. J. Biol. Chem. 276, 27455-27461 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 27455-27461
-
-
Cuevas, B.D.1
-
22
-
-
33745843997
-
Negative regulation of FcεRI-mediated signaling and mast cell function by the adaptor protein LAX
-
Zhu, M., Rhee, I., Liu, Y. & Zhang, W. Negative regulation of FcεRI-mediated signaling and mast cell function by the adaptor protein LAX. J. Biol. Chem. 281, 18408-18413 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, pp. 18408-18413
-
-
Zhu, M.1
Rhee, I.2
Liu, Y.3
Zhang, W.4
-
23
-
-
2942565987
-
Dexamethasone suppresses antigen-induced activation of phosphatidylinositol 3-kinase and downstream responses in mastrells
-
Andrade, M.V., Hiragun, T. & Beaven, M.A. Dexamethasone suppresses antigen-induced activation of phosphatidylinositol 3-kinase and downstream responses in mastrells. J. Immunol. 172, 7254-7262 (2004).
-
(2004)
J. Immunol
, vol.172
, pp. 7254-7262
-
-
Andrade, M.V.1
Hiragun, T.2
Beaven, M.A.3
-
24
-
-
0030018183
-
Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells
-
Zhang, J., Berenstein, E.H., Evans, R.L. & Siraganian, R.P. Transfection of Syk protein tyrosine kinase reconstitutes high affinity IgE receptor-mediated degranulation in a Syk-negative variant of rat basophilic leukemia RBL-2H3 cells. J. Exp. Med. 184, 71-79 (1996).
-
(1996)
J. Exp. Med
, vol.184
, pp. 71-79
-
-
Zhang, J.1
Berenstein, E.H.2
Evans, R.L.3
Siraganian, R.P.4
-
25
-
-
0032751617
-
Molecular consequences of human mast cell activation following immunoglobulin E-high-affinity immunoglobulin E receptor (IgE-FcεRI) interaction
-
Reischl, I.G., Coward, W.R. & Church, M.K. Molecular consequences of human mast cell activation following immunoglobulin E-high-affinity immunoglobulin E receptor (IgE-FcεRI) interaction. Biochem. Pharmacol. 58, 1841-1850 (1999).
-
(1999)
Biochem. Pharmacol
, vol.58
, pp. 1841-1850
-
-
Reischl, I.G.1
Coward, W.R.2
Church, M.K.3
-
26
-
-
16244393685
-
Signalling by P13K isoforms: Insights from gene-targeted mice
-
Vanhaesebroeck, B., Ali, K., Bilancio, A., Geering, B. & Foukas, L.C. Signalling by P13K isoforms: Insights from gene-targeted mice. Trends Biochem. Sci. 30, 194-204 (2005).
-
(2005)
Trends Biochem. Sci
, vol.30
, pp. 194-204
-
-
Vanhaesebroeck, B.1
Ali, K.2
Bilancio, A.3
Geering, B.4
Foukas, L.C.5
-
27
-
-
0034161386
-
Inhibition at degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cβ
-
Nechushtan, H., Leitges, M., Cohen, C., Kay, G. & Razin, E. Inhibition at degranulation and interleukin-6 production in mast cells derived from mice deficient in protein kinase Cβ. Blood 95, 1752-1757 (2000).
-
(2000)
Blood
, vol.95
, pp. 1752-1757
-
-
Nechushtan, H.1
Leitges, M.2
Cohen, C.3
Kay, G.4
Razin, E.5
-
28
-
-
0036258094
-
Protein kinase C-δ is a negative regulator of antigen-induced mast cell degranulation
-
Leitges, M. et al. Protein kinase C-δ is a negative regulator of antigen-induced mast cell degranulation. Mol. Cell. Biol. 22 3970-3980 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 3970-3980
-
-
Leitges, M.1
-
29
-
-
0031570037
-
Antigen activation of mitogen-activated protein kinase in mast cells through protein kinase C-dependent and independent pathways
-
Zhang, C., Hirasawa, N. & Beaven, M.A. Antigen activation of mitogen-activated protein kinase in mast cells through protein kinase C-dependent and independent pathways. J. Immunol. 158, 4968-4975 (1997).
-
(1997)
J. Immunol
, vol.158
, pp. 4968-4975
-
-
Zhang, C.1
Hirasawa, N.2
Beaven, M.A.3
-
30
-
-
33745043950
-
Impaired degranulation but enhanced cytokine production after FcεRI stimulation of diacylglycerol kinase ζ-deficient mast cells
-
Olenchock, B.A. et al. Impaired degranulation but enhanced cytokine production after FcεRI stimulation of diacylglycerol kinase ζ-deficient mast cells. J. Exp. Med. 203, 1471-1480 (2006).
-
(2006)
J. Exp. Med
, vol.203
, pp. 1471-1480
-
-
Olenchock, B.A.1
-
31
-
-
0034605120
-
Akt-dependent cytokine production in mast cells
-
Kitaura, J. et al. Akt-dependent cytokine production in mast cells. J. Exp. Med. 192, 729-740 (2000).
-
(2000)
J. Exp. Med
, vol.192
, pp. 729-740
-
-
Kitaura, J.1
-
32
-
-
34548312363
-
2+/calmodulin directly interacts with the pleckstrin homology domain of AKT1
-
2+/calmodulin directly interacts with the pleckstrin homology domain of AKT1. J. Biol. Chem. 282 25131-25140 (2007).
-
(2007)
J. Biol. Chem
, vol.282
, pp. 25131-25140
-
-
Dong, B.1
Valencia, C.A.2
Liu, R.3
-
33
-
-
0034705237
-
2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity
-
2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity. J. Biol. Chem. 275, 18962-18968 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 18962-18968
-
-
Popov, S.G.1
Krishna, U.M.2
Falck, J.R.3
Wilkie, T.M.4
-
34
-
-
0036733358
-
Cellular regulation of RGS proteins: Modulators and integrators of G protein signaling
-
Hollinger, S. & Hepler, J.R. Cellular regulation of RGS proteins: modulators and integrators of G protein signaling. Pharmacol. Rev. 54, 527-559 (2002).
-
(2002)
Pharmacol. Rev
, vol.54
, pp. 527-559
-
-
Hollinger, S.1
Hepler, J.R.2
-
35
-
-
0033621888
-
Impaired kit- but not FcεRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85α gene products
-
Lu-Kuo, J.M., Fruman, D.A., Joyal, D.M., Cantley, L.C. & Katz, H.R. Impaired kit- but not FcεRI-initiated mast cell activation in the absence of phosphoinositide 3-kinase p85α gene products. J. Biol. Chem. 275, 6022-6029 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 6022-6029
-
-
Lu-Kuo, J.M.1
Fruman, D.A.2
Joyal, D.M.3
Cantley, L.C.4
Katz, H.R.5
-
36
-
-
0034674462
-
RGS4 binds to membranes through an amphipathic α-helix
-
Bernstein, L.S., Grillo, A.A., Loranger, S.S. & Linder, M.E. RGS4 binds to membranes through an amphipathic α-helix. J. Biol. Chem. 275, 18520-18526 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 18520-18526
-
-
Bernstein, L.S.1
Grillo, A.A.2
Loranger, S.S.3
Linder, M.E.4
-
38
-
-
33947544164
-
RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks
-
online] 370, pe2 , doi:10.1126/stke.3702007pe3702002
-
Heximer, S.P. & Blumer, K.J. RGS proteins: Swiss army knives in seven-transmembrane domain receptor signaling networks. Sci. STKE [online] 370, pe2 (2007) (doi:10.1126/stke.3702007pe3702002).
-
(2007)
Sci. STKE
-
-
Heximer, S.P.1
Blumer, K.J.2
-
39
-
-
17344367802
-
2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors
-
2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors. Nat. Cell Biol. 7, 405-411 (2005).
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 405-411
-
-
Wang, X.1
-
40
-
-
33845299158
-
Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin
-
Liu, W. et al. Adrenergic modulation of NMDA receptors in prefrontal cortex is differentially regulated by RGS proteins and spinophilin. Proc. Natl. Acad. Sci. USA 103, 18338-18343 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 18338-18343
-
-
Liu, W.1
-
41
-
-
22844433094
-
Selective inhibition of α1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop
-
Hague, C. et al. Selective inhibition of α1A-adrenergic receptor signaling by RGS2 association with the receptor third intracellular loop. J. Biol. Chem. 280, 27289-27295 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, pp. 27289-27295
-
-
Hague, C.1
-
42
-
-
15244342101
-
Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles
-
Han, S.B. et al. Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles. Immunity 22, 343-354 (2005).
-
(2005)
Immunity
, vol.22
, pp. 343-354
-
-
Han, S.B.1
-
43
-
-
0036721767
-
RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13
-
Shi, G.X., Harrison, K., Wilson, G.L., Moratz, C. & Kehrl, J.H. RGS13 regulates germinal center B lymphocytes responsiveness to CXC chemokine ligand (CXCL)12 and CXCL13. J. Immunol. 169, 2507-2515 (2002).
-
(2002)
J. Immunol
, vol.169
, pp. 2507-2515
-
-
Shi, G.X.1
Harrison, K.2
Wilson, G.L.3
Moratz, C.4
Kehrl, J.H.5
-
44
-
-
8444248181
-
Follicular dendritic cell regulation of CXCR4-mediated germinal center CD4 T cell migration
-
Estes, J.D. et al. Follicular dendritic cell regulation of CXCR4-mediated germinal center CD4 T cell migration. J. Immunol. 173, 6169-6178 (2004).
-
(2004)
J. Immunol
, vol.173
, pp. 6169-6178
-
-
Estes, J.D.1
-
45
-
-
0033104788
-
Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes
-
Beadling, C., Druey, K.M., Richter, G., Kehrl, J.H. & Smith, K.A. Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes. J. Immunol. 162, 2677-2682 (1999).
-
(1999)
J. Immunol
, vol.162
, pp. 2677-2682
-
-
Beadling, C.1
Druey, K.M.2
Richter, G.3
Kehrl, J.H.4
Smith, K.A.5
-
46
-
-
33947673560
-
Histamine release from the basophils of control and asthmatic subjects and a comparison of gene expression between "releaser" and "nonreleaser" basophils
-
Youssef, L.A. et al. Histamine release from the basophils of control and asthmatic subjects and a comparison of gene expression between "releaser" and "nonreleaser" basophils. J. Immunol. 178, 4584-4594 (2007).
-
(2007)
J. Immunol
, vol.178
, pp. 4584-4594
-
-
Youssef, L.A.1
-
47
-
-
0033678973
-
LAT is essential for FcεRI-mediated mast cell activation
-
Saitoh, S. et al. LAT is essential for FcεRI-mediated mast cell activation. Immunity 12, 525-535 (2000).
-
(2000)
Immunity
, vol.12
, pp. 525-535
-
-
Saitoh, S.1
-
48
-
-
0027729893
-
Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor α chain gene
-
Dombrowicz, D., Flamand, V., Brigman, K.K., Koller, B.H. & Kinet, J.P. Abolition of anaphylaxis by targeted disruption of the high affinity immunoglobulin E receptor α chain gene. Cell 75, 969-976 (1993).
-
(1993)
Cell
, vol.75
, pp. 969-976
-
-
Dombrowicz, D.1
Flamand, V.2
Brigman, K.K.3
Koller, B.H.4
Kinet, J.P.5
-
49
-
-
0001764561
-
Vav1 regulates phospholipase cγ activation and calcium responses in mast cells
-
Manetz, T.S. et al. Vav1 regulates phospholipase cγ activation and calcium responses in mast cells. Mol. Cell. Biol. 21, 3763-3774 (2001).
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 3763-3774
-
-
Manetz, T.S.1
-
50
-
-
0031759170
-
Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration
-
Nagahara, H. et al. Transduction of full-length TAT fusion proteins into mammalian cells: TAT-p27Kip1 induces cell migration. Nat. Med. 4, 1449-1452 (1998).
-
(1998)
Nat. Med
, vol.4
, pp. 1449-1452
-
-
Nagahara, H.1
|