Tyrosine Phosphorylation of p85 Relieves Its Inhibitory Activity on Phosphatidylinositol 3-Kinase

Journal of Biological Chemistry

Volumn 276, Issue 29, 2001, Pages 27455-27461

  Cuevas, Bruce D ^a   Lu, Yiling ^a   Mao, Muling ^a   Zhang, Jinyi ^b   LaPushin, Ruth ^a   Siminovitch, Kathy ^b   Mills, Gordon B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSOCIATION REACTIONS; BIOCHEMISTRY; CATALYSIS; MUTAGENESIS; PHOSPHORUS COMPOUNDS; PHYSIOLOGY;

PHOSPHORYLATION;

ENZYME INHIBITION;

ASPARTIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P85; PROTEIN TYROSINE KINASE; TYROSINE; UNCLASSIFIED DRUG; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; PTPN6 PROTEIN, MOUSE; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL VIABILITY; ENZYME ACTIVITY; ENZYME REGULATION; IN VITRO STUDY; MOLECULAR INTERACTION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ANIMAL; C3H MOUSE; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; MOUSE; PHOSPHORYLATION; REPORTER GENE; SRC HOMOLOGY DOMAIN;

ANIMALIA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL LINE; GENES, REPORTER; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, INBRED C3H; NF-KAPPA B; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TYROSINE;

EID: 0035920129     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100556200     Document Type: Article

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