Negative regulation of FcεRI-mediated signaling and mast cell function by the adaptor protein LAX

Journal of Biological Chemistry

Volumn 281, Issue 27, 2006, Pages 18408-18413

  Zhu, Minghua ^a   Rhee, Inmoo ^a   Liu, Yan ^a   Zhang, Weiguo ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; BIOCHEMISTRY; CELL CULTURE; ENZYME KINETICS;

CYTOKINE PRODUCTION; DEGRANULATION; HYPERRESPONSIVENESS; MAST CELLS;

PROTEINS;

ADAPTOR PROTEIN; DINITROPHENYL ANTIBODY; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN LAX; PROTEIN P85; UNCLASSIFIED DRUG;

ANAPHYLAXIS; ANIMAL CELL; ARTICLE; BONE MARROW; CELL FUNCTION; CELL SURVIVAL; CYTOKINE PRODUCTION; GENETIC REGULATION; MAST CELL DEGRANULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SENSITIZATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; BONE MARROW CELLS; CELL DEGRANULATION; CELL SURVIVAL; GRB2 ADAPTOR PROTEIN; MAP KINASE SIGNALING SYSTEM; MAST CELLS; MEMBRANE PROTEINS; MICE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN SUBUNITS; RECEPTORS, IGE; SIGNAL TRANSDUCTION;

EID: 33745843997     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601535200     Document Type: Article

References (22)

1. Eiseman, E., and Bolen, J. B. (1992) Nature 355, 78-80
2. Pribluda, V. S., Pribluda, C., and Metzger, H. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 11246-11250
3. Minoguchi, K., Benhamou, M., Swaim, W. D., Kawakami, Y., Kawakami, T., and Siraganian, R. P. (1994) J. Biol. Chem. 269, 16902-16908
4. El-Hillal, O., Kurosaki, T., Yamamura, H., Kinet, J. P., and Scharenberg, A. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1919-1924
5. Parravicini, V., Gadina, M., Kovarova, M., Odom, S., Gonzalez-Espinosa, C., Furumoto, Y., Saitoh, S., Samelson, L. E., O'Shea, J. J., and Rivera, J. (2002) Nat. Immunol. 3, 741-748
6. Gu, H., Saito, K., Klaman, L. D., Shen, J., Fleming, T., Wang, Y., Pratt, J. C., Lin, G., Lim, B., Kinet, J. P., and Neel, B. G. (2001) Nature 412, 186-190
7. Nadler, M. J., and Kinet, J. P. (2002) Nat. Immunol. 3, 707-708
8. Ott, V. L., and Cambier, J. C. (2000) J. Allergy Clin. Immunol. 106, 429-440
9. Rivera, J. (2002) Curr. Opin. Immunol. 14, 688-693
10. Nadler, M. J., Matthews, S. A., Turner, H., and Kinet, J. P. (2000) Adv. Immunol. 76, 325-355
11. Pivniouk, V. I., Martin, T. R., Lu-Kuo, J. M., Katz, H. R., Oettgen, H. C., and Geha, R. S. (1999) J. Clin. Investig. 103, 1737-1743
12. Saitoh, S., Arudchandran, R., Manetz, T. S., Zhang, W., Sommers, C. L., Love, P. E., Rivera, J., and Samelson, L. E. (2000) Immunity 12, 525-535
13. Zhu, M., Liu, Y., Koonpaew, S., Granillo, O., and Zhang, W. (2004) J. Exp. Med. 200, 991-1000
14. Zhang, W., Sloan-Lancaster, J., Kitchen, J., Trible, R. P., and Samelson, L. E. (1998) Cell 92, 83-92
15. Zhang, W., Trible, R. P., Zhu, M., Liu, S. K., McGlade, C. J., and Samelson, L. E. (2000) J. Biol. Chem. 275, 23355-23361
16. Liu, S. K., Fang, N., Koretzky, G. A., and McGlade, C. J. (1999) Curr. Biol. 9, 67-75
17. Finco, T. S., Kadlecek, T., Zhang, W., Samelson, L. E., and Weiss, A. (1998) Immunity 9, 617-626
18. Zhang, W., Irvin, B. J., Trible, R. P., Abraham, R. T., and Samelson, L. E. (1999) Int. Immunol. 11, 943-950
19. Zhu, M., Janssen, E., Leung, K., and Zhang, W. (2002) J. Biol. Chem. 277, 46151-46158
20. Zhu, M., Granillo, O., Wen, R., Yang, K., Dai, X., Wang, D., and Zhang, W. (2005) J. Immunol. 174, 5612-5619
21. Manetz, T. S., Gonzalez-Espinosa, C., Arudchandran, R., Xirasagar, S., Tybulewicz, V., and Rivera, J. (2001) Mol. Cell. Biol. 21, 3763-3774
22. Kawakami, T., and Kitaura, J. (2005) J. Immunol. 175, 4167-4173