Involvement of reactive oxygen species in Microcystin-LR-induced cytogenotoxicity

Free Radical Research

Volumn 41, Issue 12, 2007, Pages 1326-1337

  Nong, Qingqing ^a   Komatsu, Masaharu ^a   Izumo, Kimiko ^a   Indo, Hiroko P ^b   Xu, Baohui ^a   Aoyama, Kohji ^a   Majima, Hideyuki J ^b   Horiuchi, Masahisa ^a   Morimoto, Kanehisa ^c   Takeuchi, Toru ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

CYP2E1; Cytogenotoxicity; Microcystin LR; Oxidative damage; Reactive oxygen species (ROS)

Indexed keywords

2 [6 (4' HYDROXY)PHENOXY 3H XANTHEN 3 ON 9 YL]BENZOIC ACID; 8 HYDROXYDEOXYGUANOSINE; ALLYL SULFIDE; BENZOIC ACID DERIVATIVE; CLOMETHIAZOLE; CYTOCHROME P450 2E1; LACTATE DEHYDROGENASE; MESSENGER RNA; MICROCYSTIN LR; REACTIVE OXYGEN METABOLITE; SCAVENGER; TETRAZOLIUM; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DNA STRAND BREAKAGE; ENZYME INHIBITION; GENE EXPRESSION REGULATION; GENOTOXICITY; HUMAN; HUMAN CELL; LIPID PEROXIDATION; LIVER TOXICITY; OXIDATIVE STRESS; UPREGULATION;

BACTERIAL TOXINS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; COMET ASSAY; CYTOCHROME P-450 ENZYME SYSTEM; DEOXYGUANOSINE; HUMANS; IMMUNOHISTOCHEMISTRY; L-LACTATE DEHYDROGENASE; LIVER NEOPLASMS; MICROCYSTINS; POLYMERASE CHAIN REACTION; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 37349053581     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760701704599     Document Type: Article

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