메뉴 건너뛰기




Volumn 2, Issue 11, 2007, Pages 718-724

Design and implementation of cell-based assays to model human disease

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; BETA LACTAM ANTIBIOTIC; BICALUTAMIDE; CELL NUCLEUS RECEPTOR; COMPLEMENTARY DNA; DYSTROPHIN; ESTROGEN RECEPTOR; TAMOXIFEN;

EID: 37349031430     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb700177u     Document Type: Review
Times cited : (18)

References (38)
  • 1
    • 0036045378 scopus 로고    scopus 로고
    • Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: A translational perspective
    • La Rosee, P., O'Dwyer, M. E., and Druker, B. J. (2002) Insights from pre-clinical studies for new combination treatment regimens with the Bcr-Abl kinase inhibitor imatinib mesylate (Gleevec/Glivec) in chronic myelogenous leukemia: a translational perspective, Leukemia 16, 1213-1219.
    • (2002) Leukemia , vol.16 , pp. 1213-1219
    • La Rosee, P.1    O'Dwyer, M.E.2    Druker, B.J.3
  • 4
    • 0036927254 scopus 로고    scopus 로고
    • Discovery of compounds that will prevent tau pathology
    • Kosik, K. S., Ahn, J., Stein, R., and Yeh, L. A. (2002) Discovery of compounds that will prevent tau pathology, J. Mol. Neurosci. 19, 261-266.
    • (2002) J. Mol. Neurosci , vol.19 , pp. 261-266
    • Kosik, K.S.1    Ahn, J.2    Stein, R.3    Yeh, L.A.4
  • 5
    • 0036676693 scopus 로고    scopus 로고
    • Natural product extracts that reduce accumulation of the Alzheimer's amyloid beta peptide: Selective reduction in A beta42
    • Yager, D., Watson, M., Healy, B., Eckman, E. A., and Eckman, C. B. (2002) Natural product extracts that reduce accumulation of the Alzheimer's amyloid beta peptide: selective reduction in A beta42, J. Mol. Neurosci. 19, 129-133.
    • (2002) J. Mol. Neurosci , vol.19 , pp. 129-133
    • Yager, D.1    Watson, M.2    Healy, B.3    Eckman, E.A.4    Eckman, C.B.5
  • 7
    • 33745966453 scopus 로고    scopus 로고
    • Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide
    • Utsuki, T., Yu, Q. S., Davidson, D., Chen, D., Holloway, H. W., Brossi, A., Sambamurti, K., Lahiri, D. K., Greig, N. H., and Giordano, T. (2006) Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-beta peptide, J. Pharmacol. Exp. Ther. 318, 855-862.
    • (2006) J. Pharmacol. Exp. Ther , vol.318 , pp. 855-862
    • Utsuki, T.1    Yu, Q.S.2    Davidson, D.3    Chen, D.4    Holloway, H.W.5    Brossi, A.6    Sambamurti, K.7    Lahiri, D.K.8    Greig, N.H.9    Giordano, T.10
  • 8
    • 14944372817 scopus 로고    scopus 로고
    • FDA-preapproved drugs targeted to the translational regulation and processing of the amyloid precursor protein
    • Morse, L. J., Payton, S. M., Cuny, G. D., and Rogers, J. T. (2004) FDA-preapproved drugs targeted to the translational regulation and processing of the amyloid precursor protein, J. Mol. Neurosci. 24, 129-136.
    • (2004) J. Mol. Neurosci , vol.24 , pp. 129-136
    • Morse, L.J.1    Payton, S.M.2    Cuny, G.D.3    Rogers, J.T.4
  • 10
    • 34248177330 scopus 로고    scopus 로고
    • High content screen microscopy analysis of Abeta(1-42)-induced neurite outgrowth reduction in rat primary cortical neurons: Neuroprotective effects of alpha7 neuronal nicotinic acetylcholine receptor ligands
    • Hu, M., Schurdak, M. E., Puttfarcken, P. S., El Kouhen, R., Gopalakrishnan, M., and Li, J. (2007) High content screen microscopy analysis of Abeta(1-42)-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha7 neuronal nicotinic acetylcholine receptor ligands, Brain Res. 1151, 227-35.
    • (2007) Brain Res , vol.1151 , pp. 227-235
    • Hu, M.1    Schurdak, M.E.2    Puttfarcken, P.S.3    El Kouhen, R.4    Gopalakrishnan, M.5    Li, J.6
  • 11
    • 26944458863 scopus 로고    scopus 로고
    • Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model
    • Wang, W., Duan, W., Igarashi, S., Morita, H., Nakamura, M., and Ross, C. A. (2005) Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model, Neurobiol. Dis. 20, 500-508.
    • (2005) Neurobiol. Dis , vol.20 , pp. 500-508
    • Wang, W.1    Duan, W.2    Igarashi, S.3    Morita, H.4    Nakamura, M.5    Ross, C.A.6
  • 14
    • 26844498655 scopus 로고    scopus 로고
    • The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies
    • Li, J. Y., Popovic, N., and Brundin, P. (2005) The use of the R6 transgenic mouse models of Huntington's disease in attempts to develop novel therapeutic strategies, NeuroRx 2, 447-464.
    • (2005) NeuroRx , vol.2 , pp. 447-464
    • Li, J.Y.1    Popovic, N.2    Brundin, P.3
  • 15
    • 0033494503 scopus 로고    scopus 로고
    • Early diagnosis of the Frontal variant of frontotemporal dementia: How sensitive are standard neuroimaging and neuropsychologic tests?
    • Gregory, C. A., Serra-Mestres, J., and Hodges, J. R. (1999) Early diagnosis of the Frontal variant of frontotemporal dementia: how sensitive are standard neuroimaging and neuropsychologic tests? Neuropsychiatry Neuropsychol. Behav. Neurol. 12, 128-135.
    • (1999) Neuropsychiatry Neuropsychol. Behav. Neurol , vol.12 , pp. 128-135
    • Gregory, C.A.1    Serra-Mestres, J.2    Hodges, J.R.3
  • 16
    • 0034094873 scopus 로고    scopus 로고
    • Glutamine repeats and neurogeneration
    • Zoghbi, H. Y., and Orr, H. T. (2000) Glutamine repeats and neurogeneration, Annu. Rev. Neurosci. 23, 217-247.
    • (2000) Annu. Rev. Neurosci , vol.23 , pp. 217-247
    • Zoghbi, H.Y.1    Orr, H.T.2
  • 18
    • 0036828942 scopus 로고    scopus 로고
    • The challenge of translational research - a perspective from the NINDS
    • Finkelstein, R., Miller, T., and Baughman, R. (2002) The challenge of translational research - a perspective from the NINDS, Nat. Neurosci. 5 Suppl., 1029-1030.
    • (2002) Nat. Neurosci , vol.5 , Issue.SUPPL. , pp. 1029-1030
    • Finkelstein, R.1    Miller, T.2    Baughman, R.3
  • 19
    • 0037046554 scopus 로고    scopus 로고
    • Neurologists strike gold in drug screen effort
    • Abbott, A. (2002) Neurologists strike gold in drug screen effort, Nature 417, 109.
    • (2002) Nature , vol.417 , pp. 109
    • Abbott, A.1
  • 22
    • 34247588271 scopus 로고    scopus 로고
    • Welch, E. M., Barton, E. R., Zhuo, J., Tomizawa, Y., Friesen, W. J., Trifillis, P., Paushkin, S., Patel, M., Trotta, C. R., Hwang, S., Wilde, R. G., Karp, 6., Takasugi, J., Chen, G., Jones, S., Ren, H., Moon, Y. C., Corson, D., Turpoff, A. A., Campbell, J. A., Conn, M. M., Khan, A., Almstead, N. G., Hedrick, J., Mollin, A., Risher, N., Weetall, M., Yeh, S., Branstrom, A. A., Colacino, J. M., Babiak, J., Ju, W. D., Hirawat, S., Northcutt, V. J., Miller, L. L., Spatrick, P., He, F., Kawana, M., Feng, H., Jacobson, A., Peltz, S. W., and Sweeney, H. L. (2007) PTC124 targets genetic disorders caused by nonsense mutations, Nature 447, 87-91.
    • Welch, E. M., Barton, E. R., Zhuo, J., Tomizawa, Y., Friesen, W. J., Trifillis, P., Paushkin, S., Patel, M., Trotta, C. R., Hwang, S., Wilde, R. G., Karp, 6., Takasugi, J., Chen, G., Jones, S., Ren, H., Moon, Y. C., Corson, D., Turpoff, A. A., Campbell, J. A., Conn, M. M., Khan, A., Almstead, N. G., Hedrick, J., Mollin, A., Risher, N., Weetall, M., Yeh, S., Branstrom, A. A., Colacino, J. M., Babiak, J., Ju, W. D., Hirawat, S., Northcutt, V. J., Miller, L. L., Spatrick, P., He, F., Kawana, M., Feng, H., Jacobson, A., Peltz, S. W., and Sweeney, H. L. (2007) PTC124 targets genetic disorders caused by nonsense mutations, Nature 447, 87-91.
  • 24
    • 1042292612 scopus 로고    scopus 로고
    • Advances in estrogen receptor biology: Prospects for improvements in targeted breast cancer therapy
    • Shao, W., and Brown, M. (2004) Advances in estrogen receptor biology: prospects for improvements in targeted breast cancer therapy, Breast Cancer Res. 6, 39-52.
    • (2004) Breast Cancer Res , vol.6 , pp. 39-52
    • Shao, W.1    Brown, M.2
  • 25
    • 2442601539 scopus 로고    scopus 로고
    • Interlaboratory comparison of four in vitro assays for assessing androgenic and antiandrogenic activity of environmental chemicals
    • Komer, W., Vinggaard, A. M., Terouanne, B., Ma, R., Wieloch, C., Schlumpf, M., Sultan, C., and Soto, A. M. (2004) Interlaboratory comparison of four in vitro assays for assessing androgenic and antiandrogenic activity of environmental chemicals, Environ. Health Perspect. 112, 695-702.
    • (2004) Environ. Health Perspect , vol.112 , pp. 695-702
    • Komer, W.1    Vinggaard, A.M.2    Terouanne, B.3    Ma, R.4    Wieloch, C.5    Schlumpf, M.6    Sultan, C.7    Soto, A.M.8
  • 28
    • 4143074858 scopus 로고    scopus 로고
    • High-throughput sensing and noninvasive imaging of protein nuclear transport by using reconstitution of spilt Renilla luciferase
    • Kim, S. B., Ozawa, T., Watanabe, S., and Umezawa, Y. (2004) High-throughput sensing and noninvasive imaging of protein nuclear transport by using reconstitution of spilt Renilla luciferase, Proc. Natl. Acad. Sci. U.S.A. 101, 11542-11547.
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 11542-11547
    • Kim, S.B.1    Ozawa, T.2    Watanabe, S.3    Umezawa, Y.4
  • 29
    • 1942502336 scopus 로고    scopus 로고
    • The coactivator LXXLL nuclear receptor recognition motif
    • Savkur, R. S., and Burris, T. P. (2004) The coactivator LXXLL nuclear receptor recognition motif, J. Pept. Res. 63, 207-212.
    • (2004) J. Pept. Res , vol.63 , pp. 207-212
    • Savkur, R.S.1    Burris, T.P.2
  • 31
    • 1942454742 scopus 로고    scopus 로고
    • A genetically encoded fluorescent indicator capable of discriminating estrogen agonists from antagonists in living cells
    • Awais, M., Sato, M., Sasaki, K., and Umezawa, Y. (2004) A genetically encoded fluorescent indicator capable of discriminating estrogen agonists from antagonists in living cells, Anal Chem. 76, 2181-2186.
    • (2004) Anal Chem , vol.76 , pp. 2181-2186
    • Awais, M.1    Sato, M.2    Sasaki, K.3    Umezawa, Y.4
  • 32
    • 33746086672 scopus 로고    scopus 로고
    • How good is your screening library?
    • Irwin, J. J. (2006) How good is your screening library? Curr. Opin. Chem. Biol. 10, 352-356.
    • (2006) Curr. Opin. Chem. Biol , vol.10 , pp. 352-356
    • Irwin, J.J.1
  • 35
    • 0034681144 scopus 로고    scopus 로고
    • Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor
    • Diamond, M. I., Robinson, M. R., and Yamamoto, K. R. (2000) Regulation of expanded polyglutamine protein aggregation and nuclear localization by the glucocorticoid receptor, Proc. Natl. Acad. Sci. U.S.A. 97, 657-661.
    • (2000) Proc. Natl. Acad. Sci. U.S.A , vol.97 , pp. 657-661
    • Diamond, M.I.1    Robinson, M.R.2    Yamamoto, K.R.3
  • 36
    • 11144311139 scopus 로고    scopus 로고
    • Lessons from natural molecules
    • Clardy, J., and Walsh, C. (2004) Lessons from natural molecules, Nature 432, 829-837.
    • (2004) Nature , vol.432 , pp. 829-837
    • Clardy, J.1    Walsh, C.2
  • 37
    • 17844399025 scopus 로고    scopus 로고
    • Natural products to drugs: Natural product derived compounds in clinical trials
    • Butler, M. S. (2005) Natural products to drugs: natural product derived compounds in clinical trials, Nat. Prod. Rep. 22, 162-195.
    • (2005) Nat. Prod. Rep , vol.22 , pp. 162-195
    • Butler, M.S.1
  • 38
    • 13844312649 scopus 로고    scopus 로고
    • ZINC - a free database of commercially available compounds for virtual screening
    • Irwin, J. J., and Shoichet, B. K. (2005) ZINC - a free database of commercially available compounds for virtual screening, J. Chem. Inf. Model. 45, 177-182.
    • (2005) J. Chem. Inf. Model , vol.45 , pp. 177-182
    • Irwin, J.J.1    Shoichet, B.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.