Novel synthesis of 2-aminopentanedinitriles from 2-(bromomethyl)aziridines and their transformation into 2-imino-5-methoxypyrrolidines and 5-methoxypyrrolidin-2-ones

Tetrahedron

Volumn 64, Issue 6, 2008, Pages 1064-1070

  D'hooghe, Matthias ^a   Van Nieuwenhove, Andries ^a   Van Brabandt, Willem ^a   Rottiers, Mario ^a   De Kimpe, Norbert ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Lactams; 2 (Bromomethyl)aziridines; 2 Iminopyrrolidines; Amino nitriles; Ring opening

Indexed keywords

2 (BROMOMETHYL)AZIRIDINE; 2 (CYANOMETHYL)AZIRIDINE; 2 AMINOPENTANEDINITRILE DERIVATIVE; 2 IMINO 5 METHOXYPYRROLIDINE; 2 PYRROLIDONE DERIVATIVE; 5 METHOXYPYRROLIDIN 2 ONE; ALDIMINE DERIVATIVE; ALLYLAMINE DERIVATIVE; AMINOPENTANEDINITRILE DERIVATIVE; AZIRIDINE DERIVATIVE; DIMETHYL SULFOXIDE; ENAMINE; IMINE; METHANOL; METHOXIDE SODIUM; N ACETYLIMINO DERIVATIVE; NITRILE; POTASSIUM CYANIDE; PYRROLIDINE DERIVATIVE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ACETYLATION; ARTICLE; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; CONJUGATION; PRIORITY JOURNAL; REACTION ANALYSIS; RING OPENING; SYNTHESIS;

EID: 37349026639     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2007.03.116     Document Type: Article

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