Ring opening of 2-(cyanomethyl)aziridines by acid chlorides: synthesis of novel 4-amino-2-butenenitrile derivatives through intermediate aziridinium salts

Tetrahedron Letters

Volumn 48, Issue 10, 2007, Pages 1771-1774

  D'hooghe, Matthias ^a   Vervisch, Karel ^a   Van Nieuwenhove, Andries ^a   De Kimpe, Norbert ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

2 (Bromomethyl)aziridines; Amino nitriles; Aziridinium salts; Regioselectivity; Ring opening

Indexed keywords

2 (CYANOMETHYL)AZIRIDINE DERIVATIVE; 4 AMINO 2 BUTENENITRILE DERIVATIVE; AZIRIDINE DERIVATIVE; METHYL CHLORIDE; NITRILE; TRIETHYLAMINE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL MODIFICATION; CHEMICAL REACTION; CHLORINATION; ORGANIC CHEMISTRY; RING OPENING;

EID: 33846817150     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.01.039     Document Type: Article

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