Inhibitory receptor gp49B regulates eosinophil infiltration during allergic inflammation

Journal of Leukocyte Biology

Volumn 82, Issue 6, 2007, Pages 1531-1541

  Norris, Hillary H ^a   Peterson, Mary E ^a   Stebbins, Chris C ^a   McConchie, Brittany W ^a   Bundoc, Virgilio G ^a   Trivedi, Shweta ^a   Hodges, Marcus G ^a   Anthony, Robert M ^b   Urban Jr , Joseph F ^b   Long, Eric O ^a   Keane Myers, Andrea M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b BELTSVILLE HUMAN NUTRITION RESEARCH CENTER   (United States)

Author keywords

Helminth; Mouse asthma model

Indexed keywords

GP49B RECEPTOR; RAGWEED ANTIGEN; RECEPTOR; TYROSINE; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ALLERGIC CONJUNCTIVITIS; ALLERGIC REACTION; ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCARIS SUUM; CELL ACTIVITY; CELL INFILTRATION; CONJUNCTIVA; CONTROLLED STUDY; CYTOPLASM; DEGRANULATION; EOSINOPHIL; EOSINOPHIL INFILTRATION; FEMALE; HELMINTH; INFLAMMATION; INFLAMMATORY CELL; LARVA; LUNG; MALE; MAST CELL; MOUSE; MUCOSA; NEMATODE; NEUTROPHIL; NONHUMAN; PARASITOSIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; RAGWEED;

ALLERGENS; AMBROSIA; ANIMALS; ASCARIS SUUM; BRONCHIAL PROVOCATION TESTS; CELL DEGRANULATION; CELL SEPARATION; CONJUNCTIVITIS, ALLERGIC; CYTOKINES; EOSINOPHILIA; EOSINOPHILS; FLOW CYTOMETRY; HYPERSENSITIVITY; IMMUNOGLOBULIN ISOTYPES; INFLAMMATION; LUNG; MAST CELLS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PARASITES; RECEPTORS, IMMUNOLOGIC;

ASCARIS SUUM; MUS; VERMES;

EID: 37249092433     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.1106667     Document Type: Article

References (55)

1. Keane-Myers, A. (2001) The pathogenesis of allergic conjunctivitis. Curr. Allergy Asthma Rep. 1, 550-557.
2. Wills-Karp, M. (1999) Immunologic basis of antigen-induced airway hyperresponsiveness. Annu. Rev. Immunol. 17, 255-281.
3. Busse, W. W., Lemanske, R. F. (2001) Asthma. N. Engl. J. Med. 344, 350-362.
4. Chiappara, G., Gagliardo, R., Siena, A., Bonsignore, M. R., Bousquet, J., Bonsignore, G., Vignola, A. M. (2001) Airway remodeling in the pathogenesis of asthma. Curr. Opin. Allergy Clin. Immunol. 1, 85-93.
5. Cohn, L., Elias, J. A., Chupp, G. L. (2004) Asthma: mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22, 789-815.
6. Huber, H. L., Koessler, K. K. (1922) The pathology of bronchial asthma. Arch. Intern. Med. 30, 689-760.
7. Cambier, J. C. (1997) Inhibitory receptors abound? Proc. Natl. Acad. Sci. USA 94, 5993-5995.
8. Veillette, A., Latour, S., Davidson, D. (2002) Negative regulation of immunoreceptor signaling. Annu. Rev. Immunol. 20, 669-707.
9. Katz, H. R., Austen, K. F. (1997) A newly recognized pathway for the negative regulation of mast cell-dependent hypersensitivity and inflammation mediated by an endogenous cell surface receptor of the gp49 family. J. Immunol. 158, 5065-5070.
10. Rojo, S., Burshtyn, D. N., Long, E. O., Wagtmann, N. (1997) Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells. J. Immunol. 158, 9-12.
11. McCormick, M. J., Castells, M. C., Austen, K. F., Katz, H. R. (1999) The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptor of the immunoglobulin superfamily. Immunogenetics 50, 286-294.
12. Daheshia, M., Friend, D. S., Grusby, M. J., Austen, K. F., Katz, H. R. (2001) Increased severity of local and systemic anaphylactic reactions in gp49B1-deficient mice. J. Exp. Med. 194, 227-234.
13. Katz, H. R. (2002) Inhibition of anaphylactic inflammation by the gp49B1 receptor on mast cells. Mol. Immunol. 38, 1301-1305.
14. Wang, L. L., Mehta, I. K., LeBlanc, P. A., Yokoyama, W. M. (1997) Mouse natural killer cells express gp49B1, a structural homologue of human killer inhibitory receptors. J. Immunol. 158, 13-17.
15. Zhou, J. S., Friend, D. S., Feldweg, A. M., Daheshia, M., Li, L., Austen, K. F., Katz, H. R. (2003) Prevention of lipopolysaccharide-induced microangiopathy by gp49B1: evidence for an important role for gp49B1 expression on neutrophils. J. Exp. Med. 198, 1243-1251.
16. Rojo, S., Stebbins, C. C., Peterson, M. E., Dombrowicz, D., Wagtmann, N., Long, E. O. (2000) Natural killer cells and mast cell from gp49B null mutant mice are functional. Mol. Cell. Biol. 20, 7178-7182.
17. Castells, M. C., Wu, X., Arm, J. P., Austen, K. F., Katz, H. R. (1994) Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49. J. Biol. Chem. 269, 8393-8401.
18. Katz, H. R., Vivier, E., Castells, M. C., McCormick, M. J., Chambers, J. M., Austen, K. F. (1996) Mouse mast cell gp49B1 contains two immunoreceptor tyrosine-based inhibition motifs and suppresses mast cell activation when colligated with the high-affinity Fc receptor for IgE. Proc. Natl. Acad. Sci. USA 93, 10809-10814.
19. 3 interaction inhibits antigen-induced mast cell activation. Nat. Immunol. 2, 436-442.
20. Magone, M. T., Chan, C. C., Rizzo, L. V., Kozhich, A. T., Whitcup, S. M. (1998) A novel murine model of allergic conjunctivitis. Clin. Immunol. Immunopathol. 87, 75-84.
21. Ennis, M. (2003) Neutrophils in asthma pathophysiology. Curr. Allergy Asthma Rep. 3, 159-165.
22. Rothenberg, M. E. (1998) Eosinophilia. N. Engl. J. Med. 338, 1592-1600.
23. Conroy, D. M., Williams, T. J. (2001) Eotaxin and the attraction of eosinophils to the asthmatic lung. Respir. Res. 2, 150-156.
24. Parwaresch, M. R., Walle, A. J., Arndt, D. (1976) The peripheral kinetics of human radiolabeled eosinophils. Virchows Arch. B Cell Pathol. 1, 57-66.
25. Beeson, P. B., Bass, D. A. (1977) The Eosinophil. Philadelphia, PA, USA, W.B. Saunders, 6.
26. Rothenberg, M. E., Owen Jr., W. F., Silberstein, D. S., Soberman, R. J., Austen, K. F., Stevens, R. L. (1987) Eosinophils cocultured with endothelial cells have increased survival and functional properties. Science 237, 645-647.
27. Lee, J. J., Dimina, D., Macias, M. P., Ochkur, S. I., McGarry, M. P., O'Neill, K. R., Protheroe, C., Pero, R., Nguyen, T., Cormier, S. A., Lenkiewkz, E., Colbert, D., Rinaldi, L., Ackerman, S. J., Irvin, C. G., Lee, N. A. (2004) Defining a link with asthma in mice congenitally deficient in eosinophils. Science 305, 1773-1776.
28. Humbles, A. A., Lloyd, C. M., McMillan, S. J., Friend, D. S., Xanthou, G., McKenna, E. E., Ghiran, S., Gerard, N. P., Yu, C., Orkin, S. H., Gerard, C. (2004) A critical role for eosinophils in allergic airways remodeling. Science 305, 1776-1779.
29. Klion, A. D., Law, M. A., Riemenschneider, W., McMaster, M. L., Brown, M. R., Horne, M., Karp, B., Robinson, M., Sachdev, V., Tucker, E., Turner, M., Nutman, T. B. (2004) Familial eosinophilia: a benign disorder? Blood 103, 4050-4055.
30. Tomassini, M., Tsicopoulos, A., Tai, P. C., Gruart, V., Tonnel, A. B., Prin, L., Capron, A., Capron, M. (1991) Release of granule proteins by eosinophils from allergic and nonallergic patients with eosinophilia on immunoglobulin-dependent activation. J. Allergy Clin. Immunol. 88, 365-375.
31. Gounni, A. S., Lamkhioued, B., Ochiai, K., Tanaka, Y., Delaporte, E., Capron, A., Kinet, J. P., Capron, M. (1994) High-affinity IgE receptor on eosinophils is involved in defense against parasites. Nature 367, 183-186.
32. Kita, H., Abu-Ghazaleh, R. I., Sur, S., Gleich, G. J. (1995) Eosinophil major basic protein induces degranulation and IL-8 production by human eosinophils. J. Immunol. 154, 4749-4758.
33. Rajakulasingam, K., Till, S., Ying, S., Humbert, M., Barkans, J., Sullivan, M., Meng, Q., Corrigan, C. J., Bungre, J., Grant, J. A., Kay, A. B., Durham, S. R. (1998) Increased expression of high affinity IgE receptor-α chain mRNA and protein-bearing eosinophils in human allergen-induced atopic asthma. Am. J. Respir. Crit. Care Med. 158, 233-240.
34. Lee, N. A., McGarry, M. P., Larson, K. A., Horton, M. A., Kristensen, A. B., Lee, J. J. (1997) Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies. J. Immunol. 158, 1332-1344.
35. Dawson, H. D., Beshah, E., Nishi, S., Solano-Aguilar, G., Morimoto, M., Zhao, A., Madden, K. B., Ledbetter, T. K., Dubey, J. P., Shea-Donohue, T., Lunney, J. K., Urban Jr., J. F. (2005) Localized multi-gene expression patterns support an evolving Th1/Th2 paradigm in response to infections with Toxoplasma gondii and Ascaris suum. Infect. Immun. 73, 1116-1128.
36. Schopf, L., Luccioli, S., Bundoc, V., Justice, P., Chan, C. C., Wetzel, B. J., Norris, H. H., Urban Jr., J. F., Keane-Myers, A. (2005) Differential modulation of allergic eye disease by chronic and acute Ascaris infection. Invest. Ophthalmol. Vis. Sci. 46, 2772-2780.
37. Miyazaki, D., Nakamura, T., Toda, M., Cheung-Chau, K. W., Richardson, R. M., Ono, S. J. (2005) Macrophage inflammatory protein-1 α as a costimulatory signal for mast cell-mediated immediate hypersensitivity reactions. J. Clin. Invest. 115, 434-442.
38. Al-Shami, A., Spolski, R., Kelly, J., Keane-Myers, A., Leonard, W. J. (2005) A role for TSLP in the development of inflammation in an asthma model. J. Exp. Med. 202, 829-839.
39. Borchers, M. T., Ansay, T., DeSalle, R., Daugherty, B. L., Shen, H., Metzer, M., Lee, N. A., Lee, J. J. (2002) In vitro assessment of chemokine receptor-ligand interactions mediating mouse eosinophil migration. J. Leukoc. Biol. 71, 1033-1041.
40. Abdala-Valencia, H., Earwood, J., Bansal, S., Jansen, M., Babcock, G., Garvy, B., Wills-Karp, M., Cook-Mills, J. M. (2007) Nonhematopoietic NADPH oxidase regulation of lung eosinophilia and airway hyperresponsiveness in experimentally induced asthma. Am. J. Physiol. Lung Cell. Mol. Physiol. 292, L1111-L1125.
41. Wills-Karp, M. (2004) Interleukin-13 in asthma pathogenesis. Immunol. Rev. 202, 175-190.
42. Wynn, T. A. (2003) IL-13 effector functions. Annu. Rev. Immunol. 21, 425-456.
43. Yang, M., Hogan, S. P., Mahalingam, S., Pope, S. M., Zimmermann, N., Fulkerson, P., Dent, L. A., Young, I. G., Matthaei, K. I., Rothernberg, M. E., Foster, P. S. (2003) Eotaxin and IL-5 cooperate in the lung to regulate IL-13 production and airway eosinophilia and hyperactivity. J. Allergy Clin. Immunol. 112, 935-943.
44. Schmid-Grendelmeier, P., Altznauer, F., Fischer, B., Bizer, C., Straumann, A., Menz, G., Blaser, K., Wuthrich, B., Simon, H. U. (2002) Eosinophils express functional IL-13 in eosinophilic inflammatory diseases. J. Immunol. 169, 1021-1027.
45. Reiman, R. M., Thompson, R. W., Feng, C. G., Hari, D., Knight, R., Cheever, A. W., Rosenberg, H. F., Wynn, T. A. (2006) Interleukin 5 (IL-5) augments the progression of liver fibrosis by regulating IL-13 activity. Infect. Immun. 74, 1471-1479.
46. Chu, C. C., Max, E. E., Paul, W. E. (1993) DNA rearrangement can account for in vitro switching to IgG1. J. Exp. Med. 178, 1381-1390.
47. Zhang, J. Q., Biedermann, B., Nitschke, L., Crocker, P. R. (2004) The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur. J. Immunol. 34, 1175-1184.
48. Epstein, M. M. (2004) Do mouse models of allergic asthma mimic clinical disease? Int. Arch. Allergy Immunol. 133, 84-100.
49. Sanderson, C. J. (1992) Interleukin-5, eosinophils, and disease. Blood 79, 3101-3109.
50. Miike, S., Nakao, A., Hiraguri, M., Kurasawa, K., Saito, Y., Iwamoto, I. (1999) Involvement of JAK2, but not PI 3-kinase/Akt and MAP kinase pathway, in anti-apoptotic signals of GM-CSF in human eosinophils. J. Leukoc. Biol. 65, 700-706.
51. Pazdrak, K., Schreiber, D., Forsythe, P., Justement, L., Alam, R. (1995) The intracellular signal transduction mechanism of interleukin-5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule- associated protein kinase pathway. J. Exp. Med. 181, 1827-1834.
52. Wakioka, T., Sasaki, A., Kato, R., Shouda, T., Matsumoto, A., Miyoshi, K., Tsuneoka, M., Komiya, S., Baron, R., Yoshimura, A. (2001) Spred is a Sprouty-related suppressor of Ras signaling. Nature 412, 647-651.
53. Inoue, H., Kato, R., Fukuyama, S., Nonami, A., Taniguchi, K., Matsumoto, K., Nakano, T., Tsuda, M., Matsumura, M., Kubo, M., Ishikaura, F., Moon, B. G., Takatsu, K., Nakanishi, Y., Yoshimura, A. (2005) Spred-1 negatively regulates allergen-induced airway eosinophilia and hyperresponsiveness. J. Exp. Med. 201, 73-82.
54. Williams, T. J., Jose, P. J. (2000) Role of eotaxin and related CC chemokines in allergy and asthma. Chem. Immunol. 78, 166-177.
55. Brown, D., Trowsdale, J., Allen, R. (2004) The LILR family: modulators of innate and adaptive immune pathways in health and disease. Tissue Antigens 64, 215-225.