The gp49A gene has extensive sequence conservation with the gp49B gene and provides gp49A protein, a unique member of a large family of activating and inhibitory receptors of the immunoglobulin superfamily

Immunogenetics

Volumn 50, Issue 5-6, 1999, Pages 286-294

  McCormick, Michael J ^a   Castells, Mariana C ^a   Austen, K Frank ^a   Katz, Howard R ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Gene structure; gp49A; gp49B1; Inhibitory receptors; Mast cells

Indexed keywords

DNA; GLYCOPROTEIN; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DNA FLANKING REGION; FLOW CYTOMETRY; GENE DUPLICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ORGANIZATION; INTRON; MALE; MAST CELL; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PSEUDOGENE; SEQUENCE HOMOLOGY;

ANIMALIA;

EID: 0032761483     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002510050604     Document Type: Article

References (52)

1. Alley TL, Cooper MD, Chen M, Kubagawa H (1998) Genomic structure of PIR-B, the inhibitory member of the paired immunoglobulin-like receptor genes in mice. Tissue Antigens 51 : 224-231
2. Arm JP, Gurish MF, Reynolds DS, Scott HC, Gartner CS, Austen KF, Katz HR (1991) Molecular cloning of gp49, a cell surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamily. J Biol Chem 266 : 15966-15973
3. Arm JP, Nwankwo C, Austen KF (1997) Molecular identification of a novel family of human immunoglobulin superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor. J Immunol 159 : 2342-2349
4. Arora N, Min K-U, Costa JJ, Rhim JS, Metcalfe DD (1993) Immortalization of mouse bone marrow-derived mast cells with Ad12-SV40 virus. Int Arch Allergy Immunol 100 : 319-327
5. Blery M, Kubagawa H, Chen C-C, Vely F, Cooper MD, Vivier E (1998) The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1. Proc Natl Acad Sci USA 95 : 2446-2451
6. Borges L, Hsu M-L, Fanger N, Kubin M, Cosman D (1997) A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules. J Immunol 159 : 5192-5196
7. Breathnach R, Chambon P (1981) Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem 50 : 349-383
8. Campbell KS, Cella M, Carretero M, Lopez-Botet M, Colonna M (1998) Signaling through human killer cell activating receptors triggers tyrosine phosphorylation of an associated protein complex. Eur J Immunol 28 : 599-609
9. Castells MC, Wu X, Arm JP, Austen KF, Katz HR (1994) Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49. J Biol Chem 269 : 8393-8401
10. Cella M, Dohring C, Samaridis J, Dessing M, Brockhaus M, Lanzavecchia A, Colonna M (1997) A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing. J Exp Med 185 : 1743-1751
11. Colonna M, Navarro F, Bellon T, Llano M, Garcia P, Samaridis J, Angman L, Cella M, Lopez-Botet M (1997) A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med 186 : 1809-1818
12. Colonna M, Samaridis J, Cella M, Angman L, Allen RL, O'Callaghan CA, Dunbar R, Ogg GS, Cerundolo V, Rolink A (1998) Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules. J Immunol 160 : 3096-3100
13. Colotta F, Re F, Muzio M, Bertini R, Polentarutti N, Sironi M, Giri JG, Dower SK, Sims JE, Mantovani A (1993) Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 261 : 472-475
14. Cosman D, Fanger N, Borges L, Kubin M, Chin W, Peterson L, Hsu ML (1997) A novel immunoglobulin superfamily receptor for cellular and viral MHC class I molecules. Immunity 7 : 273-282
15. Galli SJ, Dvorak AM, Marcum JA, Ishizaka T, Nabel G, Der Simonian H, Pyne K, Goldin JM, Rosenberg RD, Cantor H, Dvorak HF (1982) Mast cell clones: a model for the analysis of cellular maturation. J Cell Biol 95 : 435-444
16. Gillis P, Malter JS (1991) The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs. J Biol Chem 266 : 3172-3177
17. Gurish MF, Pear WS, Stevens RL, Scott ML, Sokol K, Ghildyal N, Webster MJ, Hu X, Austen KF, Baltimore D, Friend DS (1995) Tissue-regulated differentiation and maturation of a v-abl-immortalized mast cell-committed progenitor. Immunity 3 : 175-186
18. Hayami K, Fukuta D, Nishikawa Y, Yamashita Y, Inui M, Ohyama Y, Hikida M, Ohmori H, Takai T (1997) Molecular cloning of novel murine cell-surface glycoprotein homologous to killer cell inhibitory receptors. J Biol Chem 272 : 7320-7337
19. Katz HR, LeBlanc PA, Russell SW (1983) Two classes of mouse mast cells delineated by monoclonal antibodies. Proc Natl Acad Sci USA 80 : 5916-5918
20. Katz HR, Benson AC, Austen KF (1989) Activation- and phorbol ester-stimulated phosphorylation of a plasma membrane glycoprotein antigen expressed on mouse IL-3-dependent mast cells and serosal mast cells. J Immunol 142 : 919-926
21. Katz HR, Vivier E, Castells MC, McCormick MJ, Chambers JM, Austen KF (1996) Mouse mast cell gp49B1 contains two immunoreceptor tyrosine-based inhibition motifs and suppresses mast cell activation when coligated with the high-affinity Fc receptor for IgE. Proc Natl Acad Sci USA 93 : 10809-10814
22. Katz HR, Austen KF (1997) A newly recognized pathway for the negative regulation of mast cell-dependent hypersensitivity and inflammation mediated by an endogenous cell surface receptor of the gp49 family. J Immunol 158 : 5065-5070
23. Kubagawa H, Burrows PD, Cooper MD (1997) A novel pair of immunoglobulin-like receptors expressed by B cells and myeloid cells. Proc Natl Acad Sci USA 94 : 5261-5266
24. Kuroiwa A, Yamashita Y, Inui M, Yuasa T, Ono M, Nagabukuro A, Matsuda Y, Takai T (1998) Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5- phosphatase SHIP with gp49B1, and chromosomal assignment of the gene. J Biol Chem 273 : 1070-1074
25. Lanier LL, Corliss BC, Wu J, Leong C, Phillips JH (1998) Immunoreceptor DAP12 bearing a tyrosine-based activation motif is involved in activating NK cells. Nature 391 : 703-707
26. Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Keys JR, Landvatter SW, Strickler JE, McLaughlin MM, Siemens IR, Fisher SM, Livi GP, White JR, Adams JL, Young PR (1994) A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 372 : 739-746
27. Maeda A, Kurosaki M, Kurosaki T (1998a) Paired immunoglobulin-like receptor (PIR)-A is involved in activating mast cells through its association with Fc receptor γ chain. J Exp Med 188 : 991-995
28. Maeda A, Kurosaki M, Ono M, Takai T, Kurosaki T (1998b) Requirement of SH2-containing protein tyrosine phosphatases SHP-1 and SHP-2 for paired immunoglobulin-like receptor B (PIR-B)-mediated inhibitory signal. J Exp Med 187 : 1355-1360
29. Meyaard L, Adema GJ, Chang C, Woollatt E, Sutherland GR, Lanier LL, Phillips JH (1997) LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes. Immunity 7 : 283-290
30. Moretta A, Vitale M, Sivori S, Morelli L, Pende D, Bottino C, Moretta L (eds) Molecular basis of NK cell recognition and function. Basel: Karger (1996) Inhibitory and activatory receptors for HLA class I molecules in human natural killer cells. p 77-87
31. Munz C, Holmes N, King A, Loke YW, Colonna M, Schild H, Rammensee HG (1997) Human histocompatibility leukocyte antigen (HLA)-G molecules inhibit NKAT3 expressing natural killer cells. J Exp Med 185 : 385-391
32. 2 and 5-lipoxygenase. J Exp Med 182 : 197-206
33. 2 generation in immature mouse mast cells. J Biol Chem 270 : 3239-3246
34. Nakajima H, Samaridis J, Angman L, Colonna M (1999) Human myeloid cells express an activating ILT receptor (ILT1) that associates with Fc receptor γ-chain. J Immunol 162 : 5-8
35. National Center for Biotechnology Information/Genbank (1999) Mouse to human homology region map, Chr 10. http://www.ncbi.nlm.nih.gov/Omim/Homology/mouse10html
36. National Center for Biotechnology Information (1999) Online Mendelian Inheritance in Man. http://www.ncbi.nlm.nih.gov/Omim
37. Navarro F, Llano M, Bellon T, Colonna M, Geraghty DE, Lopez-Botet M (1999) The ILT2 (LIR1) and CD94/NKG2A NK cell receptors respectively recognize HLA-G1 and HLA-E molecules co-expressed on target cells. Eur J Immunol 29 : 277-283
38. Olcese L, Cambiaggi A, Semenzato G, Bottino C, Moretta A, Vivier E (1997) Human killer cell activatory receptors for MHC class I molecules are included in a multimeric complex expressed by natural killer cells. J Immunol 158 : 5083-5086
39. 4, chondroitin sulfate E proteoglycan, β-hexosaminidase, and histamine from cultured bone marrow-derived mouse mast cells. J Exp Med 157 : 189-201
40. Samaridis J, Colonna M (1997) Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways. Eur J Immunol 27 : 660-665
41. Sanger F, Nicklen S, Coulson AR (1977) DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74 : 5463-5467
42. Schmid CW (1996) Alu: structure, origin, evolution, significance and function of one-tenth of human DNA. Progress in Nucleic Acid Research & Molecular Biology 53 : 283-319
43. Selvakumar A, Steffens U, Dupont B (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol Rev 155 : 183-196
44. Shaw G, Kamen R (1986) A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46 : 659-667
45. Steffens U, Vyas Y, Dupont B, Selvakumar A (1998) Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptors (KIR), 1998. Tissue Antigens 51 : 398-413
46. Stubbs L, Carver EA, Shannon ME, Kim J, Geisler J, Generoso EE, Stanford BG, Dunn WC, Mohrenweiser H, Zimmermann W, Watt SM, Ashworth LK (1996) Detailed comparative map of human chromosome 19q and related regions of the mouse genome. Genomics 35 : 499-508
47. Torkar M, Norgate Z, Colonna M, Trowsdale J, Wilson MJ (1998) Isotypic variation of novel immunoglobulin-like transcript/killer cell inhibitory receptor loci in the leukocyte receptor complex. Eur J Immunol 28 : 3959-3967
48. Vales-Gomez M, Reyburn HT, Erskine RA, Strominger J (1998) Differential binding to HLA-C of p50-activating and inhibitory natural killer cell receptors. Proc Natl Acad Sci USA 95 : 14326-14331
49. Wagtmann N, Rojo S, Eichler E, Mohrenweiser H, Long EO (1997) A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors. Curr Biol 7 : 615-618
50. Winter CC, Gumperz JE, Parham P, Long EO, Wagtmann N (1998) Direct binding and functional transfer of NK cell inhibitory receptors reveal novel patterns of HLA-C allotype recognition. J Immunol 161 : 571-577
51. Yamashita Y, Ono M, Takai T (1998) Inhibitory and stimulatory functions of paired Ig-like receptor (PIR) family in RBL-2H3 cells. J Immunol 161 : 4042-4047
52. Zon LI, Gurish MF, Stevens RL, Mather C, Reynolds DS, Austen KF, Orkin SH (1991) GATA-binding transcription factors in mast cells regulate the promoter of the mast cell carboxypeptidase A gene. J Biol Chem 266 : 22948-22953