Natural killer cells and mast cells from gp49B null mutant mice are functional

Molecular and Cellular Biology

Volumn 20, Issue 19, 2000, Pages 7178-7182

  Rojo, S ^a   Stebbins, C C ^a   Peterson, M E ^a   Dombrowicz, D ^a   Wagtmann, N ^a   Long, E O ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANTIBODY SPECIFICITY; ARTICLE; BONE MARROW CELL; CELL MATURATION; CELL MUTANT; EFFECTOR CELL; GENETIC RECOMBINATION; IMMUNE RESPONSE; KILLER CELL; MAJOR HISTOCOMPATIBILITY COMPLEX; MAST CELL; MOUSE; NONHUMAN; NULL CELL; PRIORITY JOURNAL; SURVIVAL RATE; TARGET CELL;

ANIMAL; ANTIGENS, SURFACE; BONE MARROW CELLS; CYTOTOXICITY, IMMUNOLOGIC; FERTILITY; KILLER CELLS, NATURAL; MAST CELLS; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; PHENOTYPE;

EID: 0033830543     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.19.7178-7182.2000     Document Type: Article

References (17)

1. Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49
2. Anaphylaxis mediated through a humanized high affinity IgE receptor
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6. Stimulation of murine natural killer (NK) cells by a monoclonal antibody specific for the NK1.1 antigen. IL-2-activated NK cells possess additional specific stimulation pathways
7. A newly recognized pathway for the negative regulation of mast cell-dependent hypersensitivity and inflammation mediated by an endogenous cell surface receptor of the gp49 family
8. Association of tyrosine phosphatases SHP-1 and SHP-2, inositol 5-phosphatase SHIP with gp49B1, chromosomal assignment of the gene
9. NK cell receptors
10. Altered natural killer cell repertoire in Tap-1 mutant mice
11. gp49B1 inhibits IgE-initiated mast cell activation through both immunoreceptor tyrosine-based inhibitory motifs, recruitment of src homology 2 domain-containing phosphatase-1, suppression of early and late calcium mobilization
12. Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes
13. Type I transmembrane receptor with inhibitory function in mouse mast cells and NK cells
14. Production of human cells expressing individual transferred HLA-A-,-B,-C genes using an HLA-A,-B,-C null human cell line
15. Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer
16. Inducible expression of the gp49B inhibitory receptor on NK cells
17. Mouse natural killer cells express gp49B1, a structural homologue of human killer inhibitory receptors