Effects of various nonopioid receptor antagonists on the antinociceptive activity of Muntingia calabura extracts in mice

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 29, Issue 8, 2007, Pages 515-520

  Zakaria, Zainul Amiruddin ^a   Hassan, M H ^b   Nurul Aqmar, M N H ^b   Ghani, M Abd ^b   Zaid, S N H Mohd ^b   Sulaiman, M R ^c   Hanan Kumar, G ^b   Fatimah, C A ^b  

^a UNIVERSITI TEKNOLOGI MARA   (Malaysia)

^b Universiti Industri Selangor   (Malaysia)

^c UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Antinociceptive activity; Aqueous extract; Chloroform extract; Hot plate test; Muntingia calabura

Indexed keywords

ATROPINE; BICUCULLINE; CHLOROFORM; HALOPERIDOL; MECAMYLAMINE; MUNTINGIA CALABURA EXTRACT; OPIATE ANTAGONIST; PHENOXYBENZAMINE; PINDOLOL; PLANT EXTRACT; UNCLASSIFIED DRUG; YOHIMBINE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DISTILLATION; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; HOT PLATE TEST; MALE; MOUSE; NONHUMAN;

ANIMALS; ELAEOCARPACEAE; MALE; MICE; MICE, INBRED ICR; PAIN; PAIN MEASUREMENT; PLANT EXTRACTS; PLANT LEAVES; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, ADRENERGIC, ALPHA-2; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, DOPAMINE; RECEPTORS, GABA; RECEPTORS, MUSCARINIC; SIGNAL TRANSDUCTION;

EID: 37149017976     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: 10.1358/mf.2007.29.8.1119164     Document Type: Article

References (35)

1. Morton, J.F. Jamaica cherry. In: Fruits of Warm Climates. Morton, J.F. (Ed.), Miami, FL, Julia F. Morton, 1987, 65-9.
2. Jensen, M. Trees Commonly Cultivated in Southeast Asia: An Illustrated Field Guide (2nd ed). FAO Corporate Document Repository. Bangkok: Craftsman Press 1999.
3. Kaneda, N., Pezzuto, J.M., Soejarto, D.D. et al. Plant anticancer agents, XLVIII. New cytotoxic flavonoids from Muntingia calabura roots. J Nat Prod 1991, 54: 196-206.
4. Su, B.N., Park, E.J., Vigo, J.S. et al. Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. Phytochemistry 2003, 63: 335-41.
5. Zakaria, Z.A., Fatimah, C.A., Jais, A.M.M. et al. The in vitro antibacterial activity of Muntingia calabura extracts. Int J Pharmacol 2006a, 2: 290-3.
6. Zakaria, Z.A., Zaiton, H., Henie, E.F.P. et al. The in vitro antibacterial activity of Corchorus olitorius and Muntingia calabura extracts. J Pharmacol Toxicol 2006b, 1: 108-14.
7. Zakaria, Z.A., Safarul, M., Sulaiman, M.R. et al. The Antinociceptive Action of Aqueous Extract from Muntingia calabura Leaves: The Role of Opioid Receptors. Med Princ Pract 2006c, 16: 130-6.
8. Zakaria, Z.A., Sulaiman, M.R., Jais, A.M.M. et al. The involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in Muntingia calabura aqueous extract antinociception in mice. Fund Clin Pharmacol 2006d, 20: 365-72.
9. Yin, L.L., Zhu, X.Z. The involvement of central cholinergic system in (+)-matrine-induced antinociception in mice. Pharmacol Biochem Behav 2005, 80: 419-25.
10. Pieretti, S., Piaz, V.D., Matucci, R., Giovanni, M.P., Galli, A. Antinociceptive activity of a 3 (2H)-pyridazinone derivative in mice. Life Sci 1999, 65: 1381-94.
11. 2 muscarinic receptor antagonist AF-DX 116. Behav Neural Biol 1993, 60: 69-74.
12. Ono, M., Satoh, T. Pharmacological studies on lappoconitine: Possible interaction with endogenous nor-adrenergic and serotonergic pathways to induce antinociception. Jpn J Pharmacol 1992, 58: 251-7.
13. Singh, V.P., Jain, N.K., Kulkarni, S.K. On the antinociceptive effect of fluoxetine, a selective serotonin reuptake inhibitor. Brain Res 2001, 915: 218-26.
14. Anjaneluyu, M., Chopra, K. Fluoxetine attenuates thermal hyperalgesia through 5-HT1/2 receptors in streptozotocin-induced diabetic mice. Eur J Pharmacol 2004, 497: 285-92.
15. Verma, A., Kulkarni, S.K. Alpha 2-adrenoceptor- and D2-dopamine receptor-mediated analgesic response of B-HT 920. J Pharm Pharmacol 1991, 43: 131-3.
16. Zimmermann, M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 1983, 16: 109-10.
17. Wilson, S.G., Bryant, C.D., Lariviere, W.R. et al. The heritability of antinociception. II. Pharmacogenetic mediation of three over-the-counter analgesics in mice. J Pharmacol Exp Ther 2003, 305: 755-64.
18. Pini, L.A., Vitale, G., Ottani, A., Sandrini, M. Naloxone-reversible antinociception by paracetamol in the rat. J Pharmacol Exp Ther 1997, 280: 934-40.
19. Hosseinzadeh, H., Younesi, H.M. Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice. BMC Pharmacol 2002, 2: 7.
20. Hiramatsu, M., Inoue, K., Ambo, A., Sasaki, Y., Kameyama, T. Long-lasting antinociceptive effects of a novel dynorphin analogue. Br J Pharmacol 2001, 132: 1948-56.
21. Cicero, T.J., Meyer, E.R., Smithloff, B.R. Alpha adrenergic blocking agents: Antinociceptive activity and enhancement of morphine-induced analgesia. J Pharmacol Exp Ther 1974, 189: 72-82.
22. Chen, J.J., Lin, R.W., Duh, C.Y., Huang, H.Y., Chen, I.S. Flavones and cytotoxic constituents from the stem bark of Muntingia calabura. J Chin Chem Soc 2004, 51: 665-70.
23. Chen, J.J., Lee, H.H., Duh, C.Y., Chen, I.S. Cytotoxic chalcones and flavonoids from the leaves of Muntingia calabura. Planta Med 2005, 71: 970-3.
24. Oblak, M., Randic, M., Solmajer, T. Quantitative structure-activity relationship of flavonoid analogues. III. Inhibition of p56lck protein tyrosine kinase. J Chem Inf Comput Sci 2000, 40: 994-1001.
25. Meotti, F.C., Luiz, A.P., Pizzolatti, M.G., Kassuya, C.A.L., Calixto, J.B., Santos, A.R.S. Analysis of the antinociceptive effect of the flavonoid myricitrin. Evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways. J Pharmacol Exp Ther 2005, 316: 789-96.
26. Otuki, M.F., Ferreira, J., Lima, F.V. et al. Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: Evidence for participation of protein kinase C and protein kinase A pathways. J Pharmacol Exp Ther 2005, 313: 310-18.
27. Chen, C.K., Pace-Asciak, C.R. Vasorelaxing activity of resveratrol and quercetin in resveratrol and quercetin in isolated rat aorta. Gen Pharmacol 1996, 27: 363-6.
28. Middleton, E., Jr., Kandaswami, C., Theoharides, T.C. The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol Rev 2000, 52: 673-751.
29. Robak, J., Shridi, F., Wolbis, M., Krolikowska, M. Screening of the influence of flavonoids on lipoxygenase and cyclooxygenase activity, as well as on nonenzymic lipid oxidation. Pol J Pharmacol Pharm 1998, 40: 451-8.
30. Rajendran, N.N., Thirugnanasambandam, P., Viswanathan, S., Parvathavarthini, S., Ramaswamy, S. Antinociceptive pattern of flavone and its mechanism as tested by formalin assay. Ind J Exp Biol 2000, 38: 182-5.
31. Viana, G.S.B., Bandeira, M.A.M., Moura, L.C., Souza-Filho, M.V.P., Matos, F.J.A., Ribeiro, R.A. Analgesic and antiinflammatory effects of the tannin fraction from Myracrodruon urundeuva. Fr All Phytother Res 1997, 11: 118-22.
32. Naseri, M.K.G., Hamidi, M.N., Heidari, A. Vasorelaxatory effect of Vitis vinifera extract on rat aorta. Iran J Pharmaceut Sci 2005, 2: 93-9.
33. Suh, H.W., Song, D.K., Son, K.H. et al. Antinociceptive mechanisms of dipsacus saponin C administered intracerebroventricularly in the mouse. Gen Pharmacol 1996, 27: 1167-72.
34. Meotti, F.C., Ardenghi, J.V., Pretto, J.B. et al. Antinociceptive properties of coumarin, steroid and dihydrostyryl-2-pyrones from Polygala sabulosa (Polygalaceae) in mice. J Pharm Pharmacol 2006, 58: 107-12.
35. Franco, A.C., Prado, W.A. Antinociceptive effects of stimulation of discrete sites in the rat hypothalamus: Evidence for the participation of the lateral hypothalamus area in descending pain suppression mechanisms. Braz J Med Biol Res 1996, 29: 1531-41.