The antinociceptive activity of Muntingia calabura aqueous extract and the involvement of L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in its observed activity in mice

Fundamental and Clinical Pharmacology

Volumn 20, Issue 4, 2006, Pages 365-372

  Zakaria, Zainul Amiruddin ^a,b   Sulaiman, Mohd Roslan ^b   Jais, Abdul Manan Mat ^b   Somchit, Muhammad Nazrul ^b   Jayaraman, Kogilla Vani ^a   Balakhrisnan, Ganesh ^a   Abdullah, Fatimah Corazon ^a  

^a Faculty of Biotechnology and Life Sciences   (Malaysia)

^b UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Abdominal constriction test; Antinociception; Aqueous extract; L arginine nitric oxide cyclic guanosine monophosphate pathway; Muntingia calabura

Indexed keywords

ARGININE; CYCLIC GMP; METHYLENE BLUE; MUNTINGIA CALABURA EXTRACT; N(G) METHYLARGININE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

ABDOMEN; ANIMAL EXPERIMENT; ANTINOCICEPTION; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; MALE; MEDICINAL PLANT; MOUSE; MUNTINGIA CALABURA; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL;

ACETIC ACID; ANALGESICS; ANIMALS; ARGININE; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, DRUG; ELAEOCARPACEAE; ENZYME INHIBITORS; GUANYLATE CYCLASE; MALE; METHYLENE BLUE; MICE; MICE, INBRED BALB C; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OMEGA-N-METHYLARGININE; PAIN; PAIN MEASUREMENT; PLANT EXTRACTS; PLANT LEAVES; SIGNAL TRANSDUCTION;

EID: 33745839342     PISSN: 07673981     EISSN: 14728206     Source Type: Journal    
DOI: 10.1111/j.1472-8206.2006.00412.x     Document Type: Article

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