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Volumn 40, Issue 4, 2000, Pages 994-1001

Quantitative Structure-Activity Relationship of Flavonoid Analogues. 3. Inhibition of p56lck Protein Tyrosine Kinase

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; FLAVONOID; PROTEIN KINASE LCK;

EID: 0034222395     PISSN: 00952338     EISSN: None     Source Type: Journal    
DOI: 10.1021/ci000001a     Document Type: Article
Times cited : (69)

References (28)
  • 1
    • 0023885305 scopus 로고
    • The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains
    • Hanks, S. K.; Quinn, A. M.; Hunter, T. The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains. Science 1988, 241, 42-52.
    • (1988) Science , vol.241 , pp. 42-52
    • Hanks, S.K.1    Quinn, A.M.2    Hunter, T.3
  • 2
    • 0024953236 scopus 로고
    • Protein Modification: Phosphorylation on Tyrosine Residues
    • Hunter, T. Protein Modification: Phosphorylation on Tyrosine Residues. Curr. Opin. Cell Biol. 1989, 1, 1168-1181.
    • (1989) Curr. Opin. Cell Biol. , vol.1 , pp. 1168-1181
    • Hunter, T.1
  • 3
    • 0025343230 scopus 로고
    • Signal Transduction by Receptors with Tyrosine Kinase Activity
    • Ullrich, A.; Schlessinger, J. Signal Transduction by Receptors with Tyrosine Kinase Activity. Cell 1990, 61, 203-212.
    • (1990) Cell , vol.61 , pp. 203-212
    • Ullrich, A.1    Schlessinger, J.2
  • 4
    • 0023145547 scopus 로고
    • The Molecular Genetics of Cancer
    • Bishop, J. M. The Molecular Genetics of Cancer. Science 1987, 235, 305-311.
    • (1987) Science , vol.235 , pp. 305-311
    • Bishop, J.M.1
  • 5
    • 0028968949 scopus 로고
    • Tyrosine Kinase Inhibition: An Approach to Drug Development
    • Levitzki, A.; Gazit, A. Tyrosine Kinase Inhibition: An Approach to Drug Development. Science 1995, 267, 1782-1788.
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 6
    • 0026578427 scopus 로고
    • Protein-Tyrosine Kinase Inhibitors
    • Burke, R. T. Protein-Tyrosine Kinase Inhibitors. Drugs Future 1992, 17, 119-131.
    • (1992) Drugs Future , vol.17 , pp. 119-131
    • Burke, R.T.1
  • 7
    • 0026454471 scopus 로고
    • Protein-Tyrosine Kinase Inhibition: Mechanism-Based Discovery of Antitumor Agents
    • Chang, C.; Geahlen, L. R. Protein-Tyrosine Kinase Inhibition: Mechanism-Based Discovery of Antitumor Agents. J. Nat. Prod. 1992, 55, 1529-1560.
    • (1992) J. Nat. Prod. , vol.55 , pp. 1529-1560
    • Chang, C.1    Geahlen, L.R.2
  • 9
    • 0024408854 scopus 로고
    • Piceatannol (3,4,3′,5′-tetrahydroxy-trans-stilbene) is a naturally occurring protein-tyrosine kinase inhibitor
    • Geahlen, L. R.; McLaughlin, J. L. Piceatannol (3,4,3′,5′-tetrahydroxy-trans-stilbene) is a naturally occurring protein-tyrosine kinase inhibitor. Biochem. Biophys. Res. Commun. 1989, 165, 241-245.
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 241-245
    • Geahlen, L.R.1    McLaughlin, J.L.2
  • 10
    • 0024453108 scopus 로고
    • Inhibition of protein-tyrosine kinase activity by flavonoids and related compounds
    • Geahlen, L. R.; Koonchanok, M. N.; McLaughlin, J. L.; Patt, D. E. Inhibition of protein-tyrosine kinase activity by flavonoids and related compounds. J. Nat. Prod. 1989, 52, 982-986.
    • (1989) J. Nat. Prod. , vol.52 , pp. 982-986
    • Geahlen, L.R.1    Koonchanok, M.N.2    McLaughlin, J.L.3    Patt, D.E.4
  • 11
    • 0026093901 scopus 로고
    • Synthesis and Evaluation of Hydroxylated Flavones and Related Compounds as Potential Inhibitors of Protein Tyrosine Kinase p56
    • Cushman, M.; Nagarathnam, D.; Geahlen, L. R. Synthesis and Evaluation of Hydroxylated Flavones and Related Compounds as Potential Inhibitors of Protein Tyrosine Kinase p56. J. Nat. Prod. 1991, 54, 1345-1352.
    • (1991) J. Nat. Prod. , vol.54 , pp. 1345-1352
    • Cushman, M.1    Nagarathnam, D.2    Geahlen, L.R.3
  • 12
    • 0025975894 scopus 로고
    • Synthesis and Protein-Tyrosine Kinase Inhibitory Activities of Flavonoid Analogues
    • Cushman, M.; Nagarathnam, D.; Burg, L. D.; Geahlen, L. R. Synthesis and Protein-Tyrosine Kinase Inhibitory Activities of Flavonoid Analogues. J. Med. Chem. 1991, 34, 798-806.
    • (1991) J. Med. Chem. , vol.34 , pp. 798-806
    • Cushman, M.1    Nagarathnam, D.2    Burg, L.D.3    Geahlen, L.R.4
  • 13
    • 0028104631 scopus 로고
    • Synthesis and Biochemical Evaluation of a Series of Aminoflavones as Potential Inhibitors of Tyrosine Protein Kinases and Serine/Threonine Protein Kinases p56, EGFr, p60
    • Cushman, M.; Zhu, H.; Geahlen, L. R.; Kraker, J. A. Synthesis and Biochemical Evaluation of a Series of Aminoflavones as Potential Inhibitors of Tyrosine Protein Kinases and Serine/Threonine Protein Kinases p56, EGFr, p60. J. Med. Chem. 1994, 37, 3353-3362.
    • (1994) J. Med. Chem. , vol.37 , pp. 3353-3362
    • Cushman, M.1    Zhu, H.2    Geahlen, L.R.3    Kraker, J.A.4
  • 14
    • 0023897154 scopus 로고
    • Differential Effects of Flavonoids as Inhibitors of Tyrosine Protein Kinases and Serine/Threonine Protein Kinases
    • Hagiwara, M.; Inoue, S.; Tanaka, T.; Nunoki, K.; Ito, M.; Hidaka, H. Differential Effects of Flavonoids as Inhibitors of Tyrosine Protein Kinases and Serine/Threonine Protein Kinases. Biochem. Pharmacol. 1988, 37, 2987-2992.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2987-2992
    • Hagiwara, M.1    Inoue, S.2    Tanaka, T.3    Nunoki, K.4    Ito, M.5    Hidaka, H.6
  • 18
    • 0029409459 scopus 로고
    • Structure-Activity Correlation of Flavone Derivatives for Inhibition of cAMP Phosphodiesterase
    • Amic, D.; Davidovic-Amic, D.; Juric, A.; Lucic, B.; Trinajstic, N. Structure-Activity Correlation of Flavone Derivatives for Inhibition of cAMP Phosphodiesterase. J. Chem. Inf. Comput Sci. 1995, 35, 1034-1038.
    • (1995) J. Chem. Inf. Comput Sci. , vol.35 , pp. 1034-1038
    • Amic, D.1    Davidovic-Amic, D.2    Juric, A.3    Lucic, B.4    Trinajstic, N.5
  • 19
    • 0029806905 scopus 로고    scopus 로고
    • A rational approach to the design of flavones as xanthine oxidase inhibitors
    • Costantino, L.; Rastelli, G.; Albasini, A. A rational approach to the design of flavones as xanthine oxidase inhibitors. Eur. J. Med. Chem. 1996, 31, 693-699.
    • (1996) Eur. J. Med. Chem. , vol.31 , pp. 693-699
    • Costantino, L.1    Rastelli, G.2    Albasini, A.3
  • 20
    • 0023911241 scopus 로고
    • Expression of the Human T-Cell-Specific Tyrosine Kinase YT16(lck) Message in Leukemic T-Cell Lines
    • Koga, Y.; Kimura, N.; Minowada, J.; Mak, W. T. Expression of the Human T-Cell-Specific Tyrosine Kinase YT16(lck) Message in Leukemic T-Cell Lines. Cancer Res. 1988, 48, 856-859.
    • (1988) Cancer Res. , vol.48 , pp. 856-859
    • Koga, Y.1    Kimura, N.2    Minowada, J.3    Mak, W.T.4
  • 24
    • 0001728908 scopus 로고    scopus 로고
    • Quantum-Chemical Descriptors in QSAR/QSPR Studies
    • Karelson, M.; Lobanov, V. S.; Katritzky, A. R. Quantum-Chemical Descriptors in QSAR/QSPR Studies. Chem. Rev. 1996, 96, 1027-1043.
    • (1996) Chem. Rev. , vol.96 , pp. 1027-1043
    • Karelson, M.1    Lobanov, V.S.2    Katritzky, A.R.3
  • 25
    • 0001239360 scopus 로고
    • Resolution of Ambiguities in Structure-Property Studies by Use of Orthogonal Descriptors
    • Randic, M. Resolution of Ambiguities in Structure-Property Studies by Use of Orthogonal Descriptors. J. Chem. Inf. Comput. Sci. 1991, 31, 311-320.
    • (1991) J. Chem. Inf. Comput. Sci. , vol.31 , pp. 311-320
    • Randic, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.