Multi-mannosides based on a carbohydrate scaffold: Synthesis, force field development, molecular dynamics studies, and binding affinities for lectin con A

Journal of Organic Chemistry

Volumn 72, Issue 24, 2007, Pages 9032-9045

  Gouin, Sébastien G ^a   Vanquelef, Enguerran ^b   Fernández, José Manuel García ^c   Mellet, Carmen Ortiz ^d   Dupradeau, François Yves ^b   Kovensky, José ^a  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^c INSTITUTO DE INVESTIGACIONES QUÍMICAS   (Spain)

^d UNIVERSITY OF SEVILLE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLATION; BINDING SITES; CARBOHYDRATES; GRAFTING (CHEMICAL); MOLECULAR DYNAMICS; SCAFFOLDS; SYNTHESIS (CHEMICAL);

CLICK CHEMISTRY; CONCANAVALIN A; MANNOSYL LIGANDS; MULTI-VALENT MANNOSIDES;

AROMATIC COMPOUNDS;

CARBOHYDRATE DERIVATIVE; CONCANAVALIN A; GLYCOCONJUGATE; LECTIN; MANNOSIDE; TRIAZOLE;

ACETYLATION; ARTICLE; BINDING AFFINITY; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; DEACETYLATION; LECTIN BINDING; MOLECULAR DYNAMICS; ORGANIC CHEMISTRY; SYNTHESIS;

ACETYLATION; AZIDES; BINDING SITES; CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CONCANAVALIN A; LECTINS; LIGANDS; MANNOSIDES; MODELS, CHEMICAL; MOLECULAR SEQUENCE DATA; TRIAZOLES;

EID: 36649010822     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo071248a     Document Type: Article

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