Role of mitochondria in cell death induced by Photofrin®-PDT and ursodeoxycholic acid by means of SLIM

Photochemical and Photobiological Sciences

Volumn 6, Issue 12, 2007, Pages 1332-1340

  Kinzler, Ingrid ^a   Haseroth, Elke ^a   Hauser, Carmen ^a   Rück, Angelika ^a  

^a Institute for Lasertechnologies (ILM)   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; DNA FRAGMENT; PHOTOFRIN; URSODEOXYCHOLIC ACID;

APOPTOSIS; AUTOPHAGY; CANCER CELL CULTURE; CELL CULTURE; CELL DEATH; CELL VIABILITY; CONFERENCE PAPER; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; ENZYME ACTIVATION; FLUORESCENCE ANALYSIS; HEPATOBLASTOMA; HUMAN; HUMAN CELL; IMAGING; MITOCHONDRION; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN SECRETION; RESPIRATORY CHAIN; SPECTRAL RESOLVED FLUORESCENCE LIFETIME IMAGING;

EID: 36549071182     PISSN: 1474905X     EISSN: 14749092     Source Type: Journal    
DOI: 10.1039/b705919a     Document Type: Conference Paper

References (49)

1. H. C. Wolfsen Present status of photodynamic therapy for high-grade dysplasia in Barrett's esophagus J. Clin. Gastroeneterol. 2005 39 3 189 202
2. V. R. Litle J. D. Luketich N. A. Christie P. O. Buenaventura M. Alvelo-Rivera J. S. McCaughan N. T. Nguyen H. C. Fernando Photodynamic therapy as palliation for esophageal cancer: experience in 215 patients Ann. Thorac. Surg. 2003 76 5 1687 1692
3. E. Schenkman D. L. Lamm Superficial bladder cancer therapy Sci. World J. 2004 28 4 387 399
4. M. A. Ortner Photodynamic therapy in cholangiocarcinomas Best Pract. Res. Clin. Gastroenterol. 2004 18 1 147 154
5. B. U. Jones M. Helmy M. Brenner D. L. Serna J. Williams J. C. Chen J. C. Milliken Photodynamic therapy for patients with advanced non-small-cell carcinoma of the lung Clin. Lung Cancer 2001 3 1 37 41
6. C. J. Gomer N. Ruker A. L. Murphree Differential cell photosensitivity following porphyrin photodynamic therapy Cancer Res. 1988 48 4539 4542
7. X. Y. He R. A. Sikes S. Thomsen W. K. Chung S. L. Jacques Photodynamic therapy with Photofrin II induces programmed cell death in carcinoma cell lines Photochem. Photobiol. 1994 59 437 468
8. K. Takahira M. Sano H. Arai H. Hanai Apoptosis of gastric cancer cell line MKN45 by photodynamic treatment with Photofrin Lasers Med. Sci. 2004 19 89 94
9. M. Dellinger Apoptosis or necrosis following Photofrin photosensitization: influence of the incubation protocol Photochem. Photobiol. 1996 64 182 187
10. C. Fabris G. Valduga G. Miotto L. Borsetto S. Garbisa E. Reddi Photosensitization with zinc(ii) phthalocyanine as a switch in the decision between apoptosis and necrosis Cancer Res. 2001 61 20 7459 7500
11. P. Agostinis E. Buytaert H. Breyssens N. Hendrickx Regulatory pathways in photodynamic therapy induced apoptosis Photochem. Photobiol. Sci. 2004 3 8 721 729
12. N. L. Oleinick R. L. Morris I. Belichenko The role of apoptosis in response to photodynamic therapy: what, where, why and how Photochem. Photobiol. Sci. 2002 1 1 21
13. B. C. Wilson M. Olivo G. Singh Subcellular localization of Photofrin and aminolevulinic acid and photodynamic cross-resistance in vitro in radiation-induced fibrosarcoma cells sensitive or resistant to photofrin-mediated photodynamic therapy Photochem. Photobiol. 1997 65 166 176
14. D. Kessel M. Antolovich K. M. Smith The role of the Peripheral Benzodiazepine Receptor in the apoptotic response to photodynamic therapy Photochem. Photobiol. 2001 74 346 349
15. A. Verma J. Nye S. H. Snyder Characterization of porphyrin interactions with peripheral type benzodiazepine receptors Mol. Pharmacol. 1988 34 800 805
16. C. Salet G. Moreno F. Ricchelli P. Bernardi Singlet oxygen produced by photodynamic action causes inactivation of the mitochondrial permeability transition pore J. Biol. Chem. 1997 272 21938 21943
17. F. Ricchielli G. Jori S. Gobbo P. Nikolov V. Petronilli Discrimination between two steps in the mitochondrial permeability transition process Int. J. Biochem. Cell Biol. 2005 37 9 1858 1868
18. D. Kessel J. A. Caruso J. J. Reiners, Jr. Potentiation of Photodynamic Therapy by Ursodeoxycholic Acid Cancer Res. 2000 60 6985 6988
19. C. M. Rodrigues C. J. Steer The therapeutic effects of ursodeoxycholic acid as an antiapoptotic agent Expert Opin. Invest. Drugs 2001 10 7 1243 1253
20. R. E. Poupon K. D. Lindor K. Cauch-Dudek E. R. Dickson R. Poupon E. J. Heathcote Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis Gastroenterology 1997 113 884 890
21. C. M. Rodrigues C. J. Steer Mitochondrial membrane perturbations in cholestasis J. Hepatol. 2000 32 135 141
22. C. M. Rodrigues X. Ma C. Linehan-Stieers G. Fan B. T. Kren C. J. Steer Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation Cell Death Differ. 1999 6 842 854
23. G. M. Garbo M. G. Vicente V. Fingar D. Kessel Effects of ursodeoxycholic acid on photodynamic therapy in a murine tumor model Photochem. Photobiol. 2003 78 4 407 410
24. M. Müller S. Strand H. Hug E.-M. Heinemann H. Walczak W. J. Hofmann W. Stremmel P. H. Krammer P. R. Galle Drug-induced apoptosis in hepatoma cells is mediated by the CD95(APO-1/Fas) Receptor/Ligand system and involves activation of wild-type p53 J. Clin. Invest. 1997 99 3 403 413
25. E. Borenfreund J. A. Puerner Toxicity determined in vitro by morphological alterations and neutral red absorption Toxicol. Lett. 1985 24 2-3 119 124
26. A. Rück C. Hülshoff I. Kinzler W. Becker R. Steiner SLIM: A new method for molecular imaging Micr. Res. Techn. 2007 70 485 492
27. W. Becker, Advanced time-correlated single photon counting techniques, Springer Series in Chemical Physics, Springer-Verlag, Berlin, Heidelberg, 2005
28. Z. Tong G. Singh A. J. Rainbow The role of the p53 tumor suppressor in the response of human cells to Photofrin-mediated photodynamic therapy Photochem. Photobiol. 2000 71 2 201-210
29. W G Zhang X W Li L P Ma S W Wang H Y Yang Z Y Zhang Wild -type p53 protein potentiates phototoxicity of 2-BA-2-DMHA in HT29 cells expressing endogenous mutant p53 Cancer Lett. 1999 26 1-2 189 195
30. H. Schneckenburger K. König K. Kunzi-Rapp C. Westphal-Frösch A. Rück Time resolved in-vivo fluorescence of photosensitizing porphyrins J. Photochem. Photobiol., B 1993 21 143 147
31. K. König H. Schneckenburger A. Rück R. Steiner In vivo photoproduct formation during PDT with ALA-induced endogenous porphyrins J. Photochem. Photobiol., B 1993 18 287 290
32. H. Schneckenburger M. H. Gschwend R. Sailer A. Rück W. S. L. Strauß Time-resolved pH dependent fluorescence of hydrophilic porphyrins in solution and in cultivated cells J. Photochem. Photobiol., B 1995 27 251 255
33. H. Schneckenburger K. König Fluorescence decay kinetics and imaging of NAD(P)H and flavins as metabolic indicators Opt. Eng. 1992 31 7 1447 1451
34. D. Schweitzer M. Hammer F. Schweitzer R. Anders T. Doebbecke S. Schenke E. R. Gaillard In vivo measurement of time-resolved autofluorescence at the human fundus J. Biomed. Opt. 2004 9 1214 1222
35. H. Schneckenburger P. Gessler I. Pavenstädt-Grupp Measurements of Mitochondrial Deficiencies in Living Cells by Microspectrofluorometriy J. Histochem. Cytochem. 40 10 1573 1578
36. R. J. Paul H. Schneckenburger Oxygen concentration and the oxidation-reduction state of yeast: Determinations of free/bound NADH and Flavins by time-resolved spectroscopy Naturwissenschaften 1996 83 32 35
37. C. M. Rodrigues G. Fan X. Ma B. T. Kren C. J. Steer A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation J. Clin. Invest. 1998 101 2790 2799
38. A. P. Rolo C. M. Palmeira J. M. Holy K. B. Wallace Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: The switch between apoptosis and necrosis Toxicol. Sci. 2004 79 196 204
39. J. Morgan W. R. Potter A. R. Oseroff Comparison of photodynamic targets in a carcinoma cell line and its mitochondrial DNA-deficient derivative Photochem. Photobiol. 2000 71 6 747 757
40. M. Castelli J J Reiners, Jr. D. Kessel A mechanism for the proapoptic activity of ursodeoxycholic acid: effects on Bcl-2 conformation Cell Death Differ. 2004 11 906 914
41. D. Kessel M. Castelli Evidence that bcl-2 is the target of three photosensitizers that induce a rapid apoptotic response Photochem. Photobiol. 2001 74 2 318 322
42. L. E. Bröker F. A. E. Kruyt G. Giaccone Cell death independent of caspases: A review Clin. Cancer Res. 2005 11 3155 3162
43. D. E. Johnson Noncaspase proteases in apoptosis Leukemia 2000 14 9 1695 1703
44. F. Oberhammer J. W. Wilson C. Dive I. D. Morris J. A. Hickman A. E. Wakeling P. R. Walker M. Sikorska Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation EMBO J. 1993 12 9 3679 3684
45. Y.-L. Huang C.-K. Chou Bcl-2 blocks apoptotic signal of transforming growth factor-β in human hepatoma cells J. Biomed. Sci. 1998 5 185 191
46. Y. Takeda K. Nakao K. Nakata A. Kawakami H. Ida T. Ichikawa M. Shigeno Y. Kajiya K. Hamasaki A. Kato K. Eguchi Geranylgeraniol, an intermediate product in mevalonate pathway, induces apoptotic cell death in human hepatoma cells: death receptor-independent activation of caspase-8 with down-regulation of Bcl-xL expression Jpn. J. Cancer Res. 2001 92 9 918 925
47. S. Matoba J.-G Kang W. D. Patino A. Wragg M. Boehm O. Gavrilova P. J. Hurley F. Bunz P. M. Hwang p53 regulates mitochondrial respiration Science 2006 312 5780 1650 1653
48. J. Zawacka-Pankau N. Issaeva S. Hossain A. Pramanik G. Selinova A. J. Podhajska Protoporphyrin IX interacts with wild-type p53 protein and induces cell death of human colon cancer cells in a p53-dependent and-independent manner J. Biol. Chem. 2007 282 2466 2472
49. D. Kessel J. J. Reiners Cell death pathways associated with PDT Proc. SPIE 2006 6139 613902