메뉴 건너뛰기




Volumn 5, Issue 3, 1998, Pages 185-191

Bcl-2 blocks apoptotic signal of transforming growth factor-β in human hepatoma cells

Author keywords

Antioxidative enzyme; Apoptosis; Bcl 2; Reactive oxygen species; TGF

Indexed keywords

REACTIVE OXYGEN METABOLITE; TRANSFORMING GROWTH FACTOR BETA;

EID: 0031810265     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1007/bf02253468     Document Type: Article
Times cited : (36)

References (66)
  • 1
    • 0028274733 scopus 로고
    • Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum, and mitochondrial membranes
    • Akao Y, Otshuki Y, Kataoka S, Ito Y, Tsujimoto Y. Multiple subcellular localization of bcl-2: Detection in nuclear outer membrane, endoplasmic reticulum, and mitochondrial membranes. Cancer Res 54:2468-2471;1994.
    • (1994) Cancer Res , vol.54 , pp. 2468-2471
    • Akao, Y.1    Otshuki, Y.2    Kataoka, S.3    Ito, Y.4    Tsujimoto, Y.5
  • 2
    • 0027243086 scopus 로고
    • The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis
    • Allsopp TE, Wyatt S, Paterson HF, Davies AM. The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis. Cell 73:295-307;1993.
    • (1993) Cell , vol.73 , pp. 295-307
    • Allsopp, T.E.1    Wyatt, S.2    Paterson, H.F.3    Davies, A.M.4
  • 3
    • 0020576560 scopus 로고
    • Transforming growth factor β in human platelets: Identification of a major storage site, purification and characterization
    • Assoian RK, Komoryia A, Meyers CA, Sporn MB. Transforming growth factor β in human platelets: Identification of a major storage site, purification and characterization. J Biol Chem 258:7155-7160;1983.
    • (1983) J Biol Chem , vol.258 , pp. 7155-7160
    • Assoian, R.K.1    Komoryia, A.2    Meyers, C.A.3    Sporn, M.B.4
  • 5
    • 0023097347 scopus 로고
    • Flow-cytometric characterization of stimulation, free radical formation, peroxidase activity and phagocytosis of human granulocytes with 2,7-dichlorofluorescein (DCF)
    • Burow S, Valet G. Flow-cytometric characterization of stimulation, free radical formation, peroxidase activity and phagocytosis of human granulocytes with 2,7-dichlorofluorescein (DCF). Eur J Cell Biol 43:128-133;1987.
    • (1987) Eur J Cell Biol , vol.43 , pp. 128-133
    • Burow, S.1    Valet, G.2
  • 7
    • 0027250810 scopus 로고
    • Inactivation of the type-II receptor reveals two receptor pathways for the diverse TGF-β activities
    • Chen RH, Ebner R, Derynck R Inactivation of the type-II receptor reveals two receptor pathways for the diverse TGF-β activities. Science 260:1335-1338;1993.
    • (1993) Science , vol.260 , pp. 1335-1338
    • Chen, R.H.1    Ebner, R.2    Derynck, R.3
  • 8
    • 0018639079 scopus 로고
    • Isolation of biologically active ribo- Nucleic acid from sources enriched in ribonuclease
    • Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribo- nucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294-5299;1979.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 11
    • 0001524719 scopus 로고
    • Purification and initial characterization of a type β transforming growth factor from human placenta
    • Frolik CA, Dart LL, Meyers CA, Smith DM, Sporn MB. Purification and initial characterization of a type β transforming growth factor from human placenta. Proc Natl Acad Sci USA 80:3676-3680;1983.
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 3676-3680
    • Frolik, C.A.1    Dart, L.L.2    Meyers, C.A.3    Smith, D.M.4    Sporn, M.B.5
  • 12
    • 0027679506 scopus 로고
    • 1 in the rat hepatoma cell line MCA-RH7777: A possible association with tissue transglutaminase expression
    • 1 in the rat hepatoma cell line MCA-RH7777: A possible association with tissue transglutaminase expression. Hepatology 18:945-953;1993.
    • (1993) Hepatology , vol.18 , pp. 945-953
    • Fukuda, K.1    Kojiro, M.2    Chiu, J.F.3
  • 13
    • 0030584079 scopus 로고    scopus 로고
    • Apoptosis meets signal transduction: Elimination of a Bad influence
    • Gajewski TF, Thompson CB. Apoptosis meets signal transduction: Elimination of a Bad influence. Cell 87:589-592;1996.
    • (1996) Cell , vol.87 , pp. 589-592
    • Gajewski, T.F.1    Thompson, C.B.2
  • 14
    • 0026454763 scopus 로고
    • Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
    • Garcia I, Martinou I, Tsujimoto Y, Martinou JP. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258:302-304;1992.
    • (1992) Science , vol.258 , pp. 302-304
    • Garcia, I.1    Martinou, I.2    Tsujimoto, Y.3    Martinou, J.P.4
  • 15
    • 0027250810 scopus 로고
    • Inactivation of the type-II receptor reveals two receptor pathways for the diverse TGF-β activities
    • Chen RH, Ebner R, Derynck R. Inactivation of the type-II receptor reveals two receptor pathways for the diverse TGF-β activities. Science 260:1335-1338;1993.
    • (1993) Science , vol.260 , pp. 1335-1338
    • Chen, R.H.1    Ebner, R.2    Derynck, R.3
  • 16
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham F, Van der Eb A. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 52:456-457;1973.
    • (1973) Virology , vol.52 , pp. 456-457
    • Graham, F.1    Van der Eb, A.2
  • 18
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsmeyer SJ. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336;1990.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 23
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis. Science 275:1132-1136;1997.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 24
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes
    • Krajewski S, Tartaka S, Takayama S, Schibler MJ, Fenton W, Reed JC. Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res 53:4701-4714;1993.
    • (1993) Cancer Res , vol.53 , pp. 4701-4714
    • Krajewski, S.1    Tartaka, S.2    Takayama, S.3    Schibler, M.J.4    Fenton, W.5    Reed, J.C.6
  • 25
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3:614-620;1997.
    • (1997) Nat Med , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 28
    • 0027977928 scopus 로고
    • The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the mitochondrial membrane
    • Lithgow T, Van Driel R, Beryram JF, Strasser A. The protein product of the oncogene bcl-2 is a component of the nuclear envelope, the endoplasmic reticulum, and the mitochondrial membrane. Cell Growth Differ 5:411-417;1994.
    • (1994) Cell Growth Differ , vol.5 , pp. 411-417
    • Lithgow, T.1    Van Driel, R.2    Beryram, J.F.3    Strasser, A.4
  • 30
    • 0021151779 scopus 로고
    • Type beta transforming growth factor from feline sarcoma virus-transformed rat cells, isolation and biological properties
    • Massagué J. Type beta transforming growth factor from feline sarcoma virus-transformed rat cells, isolation and biological properties. J Biol Chem 259:9756-9761;1984.
    • (1984) J Biol Chem , vol.259 , pp. 9756-9761
    • Massagué, J.1
  • 31
    • 0030604542 scopus 로고    scopus 로고
    • Transforming growth factor β signaling: Receptors, transducers, and Mad proteins
    • Massagué J. Transforming growth factor β signaling: Receptors, transducers, and Mad proteins. Cell 85:947-950;1996.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 32
    • 0022550508 scopus 로고
    • Type β transforming growth factor is the primary differentiation-inducing serum factor from normal human bronchial epithelial cells
    • Masui T, Wakefield LM, Lechner JL, La Veck MA, Sporn MB, Harris CC. Type β transforming growth factor is the primary differentiation-inducing serum factor from normal human bronchial epithelial cells. Proc Natl Acad Sci USA 83:2438-2442;1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 2438-2442
    • Masui, T.1    Wakefield, L.M.2    Lechner, J.L.3    La Veck, M.A.4    Sporn, M.B.5    Harris, C.C.6
  • 33
    • 0027389763 scopus 로고
    • Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line
    • Miyashita T, Reed JC. Bcl-2 oncoprotein blocks chemotherapy-induced apoptosis in a human leukemia cell line. Blood 81:151-157;1993.
    • (1993) Blood , vol.81 , pp. 151-157
    • Miyashita, T.1    Reed, J.C.2
  • 36
    • 0025255538 scopus 로고
    • Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines
    • Nunez G, London L, Hockenbery D, Alexander M, McKearn JP, Korsmeyer SJ. Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines. J Immunol 144:3602-3610;1990.
    • (1990) J Immunol , vol.144 , pp. 3602-3610
    • Nunez, G.1    London, L.2    Hockenbery, D.3    Alexander, M.4    McKearn, J.P.5    Korsmeyer, S.J.6
  • 40
    • 0028015832 scopus 로고
    • 1 and its involvement in induction of egr-1 in mouse osteoblastic cells
    • 1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J Cell Biol 126:1079-1088;1994.
    • (1994) J Cell Biol , vol.126 , pp. 1079-1088
    • Ohba, M.1    Shibanuma, M.2    Kuroki, T.3    Nose, K.4
  • 41
    • 0027166048 scopus 로고
    • BcI-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Millman CL, Korsmeyer SJ. BcI-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74:609-619;1993.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Millman, C.L.2    Korsmeyer, S.J.3
  • 42
    • 0028556486 scopus 로고
    • Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells. Correlation with sensitivity to growth inhibition by TGF-β
    • Park K, Kim SJ, Bang YJ, Park JG, Kim NK, Roberts AB, Sporn MB. Genetic changes in the transforming growth factor β (TGF-β) type II receptor gene in human gastric cancer cells. Correlation with sensitivity to growth inhibition by TGF-β. Proc Natl Acad Sci USA 91:8772-8776;1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8772-8776
    • Park, K.1    Kim, S.J.2    Bang, Y.J.3    Park, J.G.4    Kim, N.K.5    Roberts, A.B.6    Sporn, M.B.7
  • 45
    • 0029872210 scopus 로고    scopus 로고
    • Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures
    • Sánchez A, Álvarez AM, Benito M, Fabregat I. Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures. J Biol Chem 271:7416-7422;1996.
    • (1996) J Biol Chem , vol.271 , pp. 7416-7422
    • Sánchez, A.1    Álvarez, A.M.2    Benito, M.3    Fabregat, I.4
  • 47
    • 0026725006 scopus 로고
    • Deregulated c-myb disrupts interleukin-6- Or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: Role in leukemogenesis
    • Servakumaran M, Liebermann DA, Hoffman-Liebermann B. Deregulated c-myb disrupts interleukin-6- or leukemia inhibitory factor-induced myeloid differentiation prior to c-myc: Role in leukemogenesis. Mol Cell Biol 12:2493-2500;1992.
    • (1992) Mol Cell Biol , vol.12 , pp. 2493-2500
    • Servakumaran, M.1    Liebermann, D.A.2    Hoffman-Liebermann, B.3
  • 48
    • 0027222780 scopus 로고
    • Myeloblastic leukemia cells conditionally blocked by myc-estrogen receptor chimeric transgenes for terminal differentiation coupled to growth arrest and apoptosis
    • Selvakumaran M, Liebermann DA, Hoffman-Liebermann B. Myeloblastic leukemia cells conditionally blocked by myc-estrogen receptor chimeric transgenes for terminal differentiation coupled to growth arrest and apoptosis. Blood 81:2257-2262;1993.
    • (1993) Blood , vol.81 , pp. 2257-2262
    • Selvakumaran, M.1    Liebermann, D.A.2    Hoffman-Liebermann, B.3
  • 49
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but negative selection in thymocytes
    • Sentman CL, Shutter JR, Hockenbery D, Kanagawa O, Korsmeyer SJ. bcl-2 inhibits multiple forms of apoptosis but negative selection in thymocytes. Cell 67:879-888;1991.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 51
    • 0024492086 scopus 로고
    • Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures
    • Smith CA, Williams GT, Kingston R, Jenkinson EJ, Owen JT. Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures. Nature 337:181-184;1989.
    • (1989) Nature , vol.337 , pp. 181-184
    • Smith, C.A.1    Williams, G.T.2    Kingston, R.3    Jenkinson, E.J.4    Owen, J.T.5
  • 52
    • 0023597604 scopus 로고
    • Some recent advances in the chemistry and biology of transforming growth factor-beta
    • Sporn MB, Roberts AB, Wakefield LM, deCrombrugghe B. Some recent advances in the chemistry and biology of transforming growth factor-beta. J Cell Ciol 105:1039-1045;1987.
    • (1987) J Cell Ciol , vol.105 , pp. 1039-1045
    • Sporn, M.B.1    Roberts, A.B.2    Wakefield, L.M.3    DeCrombrugghe, B.4
  • 53
    • 0028910217 scopus 로고
    • The bcl-2 oncoprotein functions as a pro-oxidant
    • Steinman HM. The bcl-2 oncoprotein functions as a pro-oxidant. J Biol Chem 270:3487-3490;1995.
    • (1995) J Biol Chem , vol.270 , pp. 3487-3490
    • Steinman, H.M.1
  • 56
    • 0024454762 scopus 로고
    • Stress-resistance conferred by high level of bcl-2α protein in human B lymphoblastoid cell
    • Tsujimoto Y. Stress-resistance conferred by high level of bcl-2α protein in human B lymphoblastoid cell. Oncogene 4:1331-1336;1989.
    • (1989) Oncogene , vol.4 , pp. 1331-1336
    • Tsujimoto, Y.1
  • 57
    • 0024522585 scopus 로고
    • Overexpression of the human Bcl-2 gene product results in growth enhancement of Epstein-Barr virus-immortalized B cells
    • Tsujimoto Y. Overexpression of the human Bcl-2 gene product results in growth enhancement of Epstein-Barr virus-immortalized B cells. Proc Natl Acad Sci USA 86:1958-1962;1989.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 1958-1962
    • Tsujimoto, Y.1
  • 58
    • 0022878180 scopus 로고
    • Human liver glutathione-S-transferase: Complete primary sequence of an Ha subunit cDNA
    • Tu C-PD, Qian B. Human liver glutathione-S-transferase: complete primary sequence of an Ha subunit cDNA. Biochem Biophys Res Commun 141:229-237;1986.
    • (1986) Biochem Biophys Res Commun , vol.141 , pp. 229-237
    • Tu, C.-P.D.1    Qian, B.2
  • 59
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, Adams JM. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335:440-442;1988.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 60
    • 0028326952 scopus 로고
    • An evolutionary perspective on apoptosis
    • Vaux DL, Haecker G, Strasser A. An evolutionary perspective on apoptosis. Cell 76:777-779;1993.
    • (1993) Cell , vol.76 , pp. 777-779
    • Vaux, D.L.1    Haecker, G.2    Strasser, A.3
  • 61
    • 0029941824 scopus 로고    scopus 로고
    • Interaction of transforming growth factor-β receptor I with farnesyl-protein transferase-α in yeast and mammalian cells
    • Ventura F, Liu F, Doody J, Massagué J. Interaction of transforming growth factor-β receptor I with farnesyl-protein transferase-α in yeast and mammalian cells. J Biol Chem 271:13931-13934;1996.
    • (1996) J Biol Chem , vol.271 , pp. 13931-13934
    • Ventura, F.1    Liu, F.2    Doody, J.3    Massagué, J.4
  • 62
    • 0027196091 scopus 로고
    • Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis
    • Walton MI, Whysong D, O'Connor PM, Hockenbery D, Korsmeyer SJ, Kohn KW. Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis. Cancer Res 53:1853-1861;1993.
    • (1993) Cancer Res , vol.53 , pp. 1853-1861
    • Walton, M.I.1    Whysong, D.2    O'Connor, P.M.3    Hockenbery, D.4    Korsmeyer, S.J.5    Kohn, K.W.6
  • 63
    • 0345498292 scopus 로고    scopus 로고
    • Bcl-2 targets the protein kinase Raf-1 to mitochondria
    • Wang HG, Rapp UR, Reed JC. Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 87:629-638;1996.
    • (1996) Cell , vol.87 , pp. 629-638
    • Wang, H.G.1    Rapp, U.R.2    Reed, J.C.3
  • 64
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • White E. Life, death, and the pursuit of apoptosis. Genes Dev 10:1-15;1996.
    • (1996) Genes Dev , vol.10 , pp. 1-15
    • White, E.1
  • 65
    • 0029551805 scopus 로고
    • Identification of a member of the MAPKKK family as a potential mediator of transforming growth factor β signal transduction
    • Yamaguchi K, Shirakabe K, Shibuya H, Irie K, Oishi I, Ueno N, Taniguchi T, Nishida E, Matsumoto K. Identification of a member of the MAPKKK family as a potential mediator of transforming growth factor β signal transduction. Science 270:2008-2011;1995.
    • (1995) Science , vol.270 , pp. 2008-2011
    • Yamaguchi, K.1    Shirakabe, K.2    Shibuya, H.3    Irie, K.4    Oishi, I.5    Ueno, N.6    Taniguchi, T.7    Nishida, E.8    Matsumoto, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.