Subcellular Localization of Photofrin® and Aminolevulinic Acid and Photodynamic Cross-Resistance in Vitro in Radiation-Induced Fibrosarcoma Cells Sensitive or Resistant to Photofrin-Mediated Photodynamic Therapy

Photochemistry and Photobiology

Volumn 65, Issue 1, 1997, Pages 166-176

  Wilson, B C ^a,c   Olivo, M ^b   Singh, G ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID; HEMATOPORPHYRIN DERIVATIVE; PHOTOFRIN II;

ANIMAL; ARTICLE; CELL CULTURE; CELL FRACTIONATION; FIBROSARCOMA; METABOLISM; PHOTOCHEMOTHERAPY;

AMINOLEVULINIC ACID; ANIMALS; DIHEMATOPORPHYRIN ETHER; FIBROSARCOMA; HEMATOPORPHYRIN DERIVATIVE; PHOTOCHEMOTHERAPY; SUBCELLULAR FRACTIONS; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0031045060     PISSN: 00318655     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-1097.1997.tb01894.x     Document Type: Article

References (42)

1. Henderson, B. W. and T. J. Dougherty (1992) How does photodynamic therapy work? Photochem. Photobiol. 55, 145-157.
2. Berns, M. W., A. Dahlman, F. M. Johnson, R. Burns, D. Sperling, M. Guiltinan, A. Siemens, R. Walter, W. Wright, M. Hammer-Wilson and A. Wile (1982) In vitro cellular effects of hematoporphyrin derivative. Cancer Res. 42, 2325-2329.
3. Moan, J., J. V. Johannessen, T. Christensen, T. Espevik and J. B. Mcghie (1982) Porphyrin sensitized photoinactivation of human cells in vitro. Am. J. Pathol. 109, 184-192
4. Shulok, J. R., M. H. Wade and C.-W. Lin (1990) Subcellular localization of hematoporphyrin derivative in bladder tumor cells in culture. Photochem. Photobiol. 51, 451-457.
5. Hilf, R., S. L. Gibson, D. P. Penney, T. L. Cheekier and R. C. Bryant (1989) Mitochondria in cancer cells as targets of photodynamic therapy. Proc. Soc. Photo-Opt. Instrum. Eng. 847, 2-10.
6. Salet, C. and G. Moreno (1990) Photosensitization of mitochondria: molecular and cellular aspects. J. Photochem. Photobiol. B5, 133-150.
7. Woodburn, K. W., N. J. Vardaxis, J. S. Hill, A. H. Kaye and D. R. Phillips (1992) Subcellular localization of porphyrins using confocal laser scanning microscopy. Photochem. Photobiol. 54, 725-732.
8. Woodburn, K. W., N. J. Vardaxis, A. A. Kaye, J. A. Reiss and D. R. Phillips (1992) Evaluation of porphyrin characteristics required for photodynamic therapy. Photochem. Photobiol. 55, 697-704.
9. Verma, A., J. Nye and S. H. Synder (1987) Porphyrins are endogenous ligands for the mitochondrial (peripheral type) benzodiazepine receptor. Proc. Natl. Acad. Sci. USA 84, 2256-2261.
10. Roding, J., A. Naujokand and H. W. Zimmerman (1986) Effects on ethidium bromide, tetamethylethidium bromide and betadine B on the ultrastructural of HeLA cell mitochondria in situ. Histochemistry 85, 215-222.
11. Oseroff, A. R., D. Ohuoha, G. Ara, D. McAuliffe, J. Foley and L. Cincotta (1986) Intramitochondrial dyes allow selective in vitro photolysis of carcinoma cells. Proc. Natl. Acad. Sci. USA 83, 9729-9733.
12. Hilf, R., S. Murant, U. Narayanan and S. L. Gibson (1986) Relationship of mitochondrial function of cellular adenosine triphosphate levels to hematoporphyrin derivative of photosenstitization in R3230AC mammary tumours. Cancer Res. 46, 211-217.
13. Hilf, R., S. L. Gibson, R. S. Murant, T. L. Cheekier and R. G. Bryant (1987) Early biochemical responses to photodynamic therapy monitored by NMR spectrocsopy. Photochem. Photobiol. 46, 809-817
14. Singh, G., B. C. Wilson, S. M. Sharkey, G. P. Browman and P. Deschamps (1991) Resistance to photodynamic therapy in radiation induced fibrosarcoma-1 and Chinese hamster ovary, multi drug resistant cells in vitro. Photochem. Photobiol. 54, 307-312.
15. Luna, M. C. and C. J. Gomer (1991) Isolation and initial characterization of mouse tumour resistant to porphyrin-mediated photodynamic therapy. Cancer Res. 51, 4243-4249.
16. Sharkey, S. M., G. Singh, R. Moorehead and B. C. Wilson (1992) Characterization of RIF cells resistant to Photofrin-PDT in vitro. In Photodynamic Therapy and Biomedical Lasers (Edited by P. Spinelli, M. Dal Fante and R. Marchesini), pp. 727-731. Elsevier Science, Amsterdam.
17. Sharkey, S. M., B. C. Wilson, R. Moorehead and G. Singh (1993) Mitochondrial alterations in photodynamic therapy resistant cells. Cancer Res. 53, 4994-4999.
18. Hackenbrock, C. R. (1968) Ultrastructural basis for metabolically linked mechanical activity in mitochondria. J. Cell Biol. 37, 345-369.
19. Hackenbrock, C. R., E. C. Rehn, E. C. Weinbach and J. J. Lemasters (1971) Oxidative phosphorylation and ultrastructural transformation in mitochondria in the intact ascites tumour cell. J. Cell Biol. 51, 123-137.
20. Moorehead, R. A., S. G. Armstrong, B. C. Wilson and G. Singh (1993) Cross-resistance to cisplatin in cells resistant to Photofrin-mediated photodynamic therapy. Cancer Res. 54, 2556-2559.
21. Haugland, R. (1994) Molecular probes. In Handbook of Fluorescent Probes and Research Chemicals (Edited by K. D. Larison), pp. 215-217. Molecular Probes Inc., Eugene, OR.
22. Chen, L. B. (1989) In Fluorescence Microscopy of Living Cells in Culture, Part A (Edited by D. L. Taylor and Y. Wang), pp. 103-123. Academic Press, NY.
23. Bernal, S. D., H. M. Shapiro and L. B. Chen (1982) Monitoring the effect of anticancer drugs on LI210 cells by a mitochondrial probe, rhodamine 123. Int. J. Cancer 30, 219-224.
24. Maftah, A., J. M. Petit, M. H. Rainaud and R. Julien (1989) 10-N nonyl acridine orange: a fluorescent probe which stains mitochondria independently of their energetic state. Biochem. Biophys. Res. Commun. 164, 185-190.
25. Petit, J. M., A. Maftah, M. H. Ratinaud and R. Julien (1992) 10N-nonyl acridine orange interacts with cardiolipins and allows the quantification of this phospholipid in isolated mitochondria. Eur. J. Biochem. 209, 269-273.
26. Marcus, S. L., R. S. Sobel, A. L. Golub, R. L Carroll, S. Lundahl and D. G. Shulman (1996) Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): current clinical and developmental status. J. Clin. Laser Med. Surg. 14, 59-66.
27. Kennedy, J. C. and R. H. Pottier (1992) Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy. J. Photochem. Photobiol. B14, 275-292.
28. Rebiez, N., C. C. Rebeiz, S. Arkins, K. W. Kelley and C. A. Rebeiz (1992) Photodestruction of tumour cells by induction of endogenous accumulation of protoporphyrin IX: enhancement by 1,10-phenanthroline. Photochem. Photobiol. 55, 431-435.
29. Moore, M. R., K. E. L. McColl, C. Rimington and A. Goldberg (1987) Porphyrins and enzymes of the heme biosynthesis pathway. In Disorders of Porphyrin Metabolism (Edited by M. R. Moore, K. E. L. McColl, C. Rimington and A. Goldberg), pp. 21-72. Plenum Press, NY.
30. Dellinger, M. (1996) Apoptosis or necrosis following Photofrin photosensitization: influence of the incubation protocol. Photochem. Photobiol. 64, 182-187.
31. Hanzlik, C. A., R. A. Knox, S. L. Gibson and R. Hilf (1989) Picosecond fluorescence of R3230 Ac mammary carcinoma mitochondria after treatment with hematoporphyrin derivative and Photofrin II in vivo. Photochem. Photobiol. 51, 45-53.
32. Gibson, S. L., R. S. Murant, M. D. Chazen, M. E. Kelly and R. Hilf (1989) In vitro photosensitization of tumour cell enzymes by Photofrin II administered in vivo. Br. J. Cancer 59, 47-53.
33. Atlante, A., S. Passarella, E. Quagliariello, G. Moreno and C. Salet (1989) Haematoporphyrin derivative (Photofrin II) photosensitization of isolated mitochondria: inhibition of ADP/ATP translocator. J. Photochem. Photobiol. B4, 35-46.
34. 31P nuclear magnetic resonance. Biochemistry 24, 3821-3826.
35. Dougherty, T. J. (1987) Photosensitizers: therapy and detection of malignant tumours. Photochem. Photobiol. 45, 879-889.
36. Iinuma, S., S. S. Farshi, B. Ortel and T. Hasan (1994) A mechanistic study of cellular photodestruction with 5-aminolaevulinic acid-induced porphyrin. Br. J. Cancer 70, 21-28.
37. Fukuda, A., A. M. C. Battle and P. A. Riley (1993) Kinetics of porphyrin accumulation in cultured epithelial cells exposed to ALA. Int. J. Biochem. 25, 1407-1410.
38. Dailey, H. A. and A. Smith (1984) Differential interactions of porphyrin used in photoradiation therapy with ferrochelatase. Biochem J. 223, 42-45.
39. Kreig, M. and D. G. Whitten (1984) Self-sensitized photo-oxidation of protoporphyrin IX and related porphyrins in erythrocyte ghosts and microemulsion: a novel photo-oxidation pathway involving singlet oxygen. J. Photochem. 25, 235-252.
40. Sandberg, S. and I. Romslo (1981) Phototoxicity of protoporphyrin as related to its subcellular localization in mice livers after short-term feeding with griseofulvin. J. Biochem. 198, 67-74.
41. Koller, M. E. and I. Romslo (1980) Uptake of protoporphyrin IX by isolated rat liver mitochondria. Biochem. J. 188, 329-335.
42. Moan, J. and K. Berg (1991) The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen. Photochem. Photobiol. 53, 549-553.