-
1
-
-
0032766426
-
Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells
-
Agarwal B, Bhendwal S, Halmos B et al. 1999 Lovastatin augments apoptosis induced by chemotherapeutic agents in colon cancer cells. Clinical Cancer Research 5, 2223-2229.
-
(1999)
Clinical Cancer Research
, vol.5
, pp. 2223-2229
-
-
Agarwal, B.1
Bhendwal, S.2
Halmos, B.3
-
3
-
-
0032438571
-
Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation
-
Cheng AM, Saxton TM, Sakai R, et al. 1998 Mammalian Grb2 regulates multiple steps in embryonic development and malignant transformation. Cell 95, 793-803.
-
(1998)
Cell
, vol.95
, pp. 793-803
-
-
Cheng, A.M.1
Saxton, T.M.2
Sakai, R.3
-
4
-
-
0035132669
-
Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: Therapeutic implications
-
Dimitroulakos J, Ye LY, Benzaquen M et al. 2001 Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications. Clinical Cancer Research 7, 158-167.
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 158-167
-
-
Dimitroulakos, J.1
Ye, L.Y.2
Benzaquen, M.3
-
5
-
-
0348103716
-
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells
-
Draper JS, Smith K, Gokhale P et al. 2004 Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nature Biotechnology 22, 53-54.
-
(2004)
Nature Biotechnology
, vol.22
, pp. 53-54
-
-
Draper, J.S.1
Smith, K.2
Gokhale, P.3
-
6
-
-
33646551808
-
Fibroblast growth factor signaling in embryonic and cancer stem cells
-
Dvorak P, Dvorakova D, Hampl A 2006 Fibroblast growth factor signaling in embryonic and cancer stem cells. FEBS Letters 580, 2869-2874.
-
(2006)
FEBS Letters
, vol.580
, pp. 2869-2874
-
-
Dvorak, P.1
Dvorakova, D.2
Hampl, A.3
-
7
-
-
0032851111
-
Sterols and isoprenoids: Signaling molecules derived from the cholesterol biosynthetic pathway
-
Edwards PA, Ericsson J 1999 Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annual Review of Biochemistry 68, 157-185.
-
(1999)
Annual Review of Biochemistry
, vol.68
, pp. 157-185
-
-
Edwards, P.A.1
Ericsson, J.2
-
8
-
-
27744512983
-
Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells
-
Enver T, Soneji S, Joshi C et al. 2005 Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells. Human Molecular Genetics 14, 3129-3140.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 3129-3140
-
-
Enver, T.1
Soneji, S.2
Joshi, C.3
-
9
-
-
2942641691
-
Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis
-
Gniadecki R 2004 Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis. Biochemical and Biophysical Research Communications 320, 165-169.
-
(2004)
Biochemical and Biophysical Research Communications
, vol.320
, pp. 165-169
-
-
Gniadecki, R.1
-
10
-
-
19444376167
-
Statins and cancer-beyond the 'one drug, one disease' model
-
Hawk E, Viner JL 2005 Statins and cancer-beyond the 'one drug, one disease' model. New England Journal of Medicine 352, 2238-2239.
-
(2005)
New England Journal of Medicine
, vol.352
, pp. 2238-2239
-
-
Hawk, E.1
Viner, J.L.2
-
11
-
-
0026440561
-
Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family
-
Jones CM, Simon-Chazottes D, Guenet JL et al. 1992 Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family. Molecular Endocrinology 6, 1961-1968.
-
(1992)
Molecular Endocrinology
, vol.6
, pp. 1961-1968
-
-
Jones, C.M.1
Simon-Chazottes, D.2
Guenet, J.L.3
-
12
-
-
1842788119
-
Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas
-
Katano H, Pesnicak L, Cohen JI 2004 Simvastatin induces apoptosis of Epstein-Barr virus (EBV)-transformed lymphoblastoid cell lines and delays development of EBV lymphomas. Proceedings of the National Academy of Science of the USA 101, 4960-4965.
-
(2004)
Proceedings of the National Academy of Science of the USA
, vol.101
, pp. 4960-4965
-
-
Katano, H.1
Pesnicak, L.2
Cohen, J.I.3
-
13
-
-
34547202193
-
Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation
-
Lee MH, Cho YS, Han YM 2007 Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation. Stem Cells 25, 1654-1663.
-
(2007)
Stem Cells
, vol.25
, pp. 1654-1663
-
-
Lee, M.H.1
Cho, Y.S.2
Han, Y.M.3
-
14
-
-
14844313647
-
Role of survivin and its splice variants in tumorigenesis
-
Li F 2005 Role of survivin and its splice variants in tumorigenesis. British Journal of Cancer 92, 212-216.
-
(2005)
British Journal of Cancer
, vol.92
, pp. 212-216
-
-
Li, F.1
-
15
-
-
0033584938
-
Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s)
-
Li L, Patty M, Nicholas LK et al. 1999 Integrin-dependent leukocyte adhesion involves geranylgeranylated protein(s). Journal of Biological Chemistry 274, 33334-33340.
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 33334-33340
-
-
Li, L.1
Patty, M.2
Nicholas, L.K.3
-
16
-
-
0032506524
-
Control of apoptosis and mitotic spindle checkpoint by survivin
-
Li F, Ambrosini G, Chu EY et al. 1998 Control of apoptosis and mitotic spindle checkpoint by survivin. Nature 396, 580-584.
-
(1998)
Nature
, vol.396
, pp. 580-584
-
-
Li, F.1
Ambrosini, G.2
Chu, E.Y.3
-
17
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta (CT)) method
-
Livak KJ, Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta (CT)) method. Methods 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
18
-
-
0037057629
-
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
-
Marsden VS, O'Connor L, O'Reilly LA et al. 2002 Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome. Nature 419, 634-637.
-
(2002)
Nature
, vol.419
, pp. 634-637
-
-
Marsden, V.S.1
O'Connor, L.2
O'Reilly, L.A.3
-
19
-
-
18844442326
-
Statins and cholesterol lowering after a cancer diagnosis: Why not?
-
Moyad MA, Merrick GS 2005 Statins and cholesterol lowering after a cancer diagnosis: why not? Urologic Oncology 23, 49-55.
-
(2005)
Urologic Oncology
, vol.23
, pp. 49-55
-
-
Moyad, M.A.1
Merrick, G.S.2
-
20
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
O'Brien CA, Pollett A, Gallinger S et al. 2007 A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 445, 106-110.
-
(2007)
Nature
, vol.445
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
-
21
-
-
0342657718
-
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
-
Olie RA, Simoes-Wust AP, Baumann B et al. 2000 A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Research 60, 2805-2809.
-
(2000)
Cancer Research
, vol.60
, pp. 2805-2809
-
-
Olie, R.A.1
Simoes-Wust, A.P.2
Baumann, B.3
-
22
-
-
0027166048
-
Bcl-2 heterodimers in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Oltvai ZN, Milliman CL, Korsmeyer SJ 1993 Bcl-2 heterodimers in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619.
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
23
-
-
0029664582
-
Sensitivity of C3H 10T1/2 cells to radiation-induced killing and neoplastic transformation as a function of cell cycle
-
Pazzaglia S, Saran A, Pariset L et al. 1996 Sensitivity of C3H 10T1/2 cells to radiation-induced killing and neoplastic transformation as a function of cell cycle. International Journal of Radiation Biology 69, 57-65.
-
(1996)
International Journal of Radiation Biology
, vol.69
, pp. 57-65
-
-
Pazzaglia, S.1
Saran, A.2
Pariset, L.3
-
24
-
-
33745008414
-
Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: A tool for human embryonic stem cell research
-
Plaia TW, Josephson R, Liu Y et al. 2006 Characterization of a new NIH-registered variant human embryonic stem cell line, BG01V: a tool for human embryonic stem cell research. Stem Cells 24, 531-546.
-
(2006)
Stem Cells
, vol.24
, pp. 531-546
-
-
Plaia, T.W.1
Josephson, R.2
Liu, Y.3
-
26
-
-
33644864033
-
Neurotrophins mediate human embryonic stem cell survival
-
Pyle AD, Lock LF, Donovan PJ 2006 Neurotrophins mediate human embryonic stem cell survival. Nature Biotechnology 24, 344-350.
-
(2006)
Nature Biotechnology
, vol.24
, pp. 344-350
-
-
Pyle, A.D.1
Lock, L.F.2
Donovan, P.J.3
-
27
-
-
0033529171
-
Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase
-
Rao S, Porter DC, Chen X et al. 1999 Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. Proceedings of the National Academy of Science of the USA 96, 7797-7802.
-
(1999)
Proceedings of the National Academy of Science of the USA
, vol.96
, pp. 7797-7802
-
-
Rao, S.1
Porter, D.C.2
Chen, X.3
-
29
-
-
0035499267
-
Stem cells, cancer, and cancer stem cells
-
Reya T, Morrison SJ, Clarke MF et al. 2001 Stem cells, cancer, and cancer stem cells. Nature 414, 105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
-
30
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E et al. 2007 Identification and expansion of human colon-cancer-initiating cells. Nature 445, 111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
-
31
-
-
0346250854
-
The transcriptome profile of human embryonic stem cells as defined by SAGE
-
Richards M, Tan SP, Tan JH et al. 2004 The transcriptome profile of human embryonic stem cells as defined by SAGE. Stem Cells 22, 51-64.
-
(2004)
Stem Cells
, vol.22
, pp. 51-64
-
-
Richards, M.1
Tan, S.P.2
Tan, J.H.3
-
32
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L et al. 2004 Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nature Medicine 10, 55-63.
-
(2004)
Nature Medicine
, vol.10
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
-
33
-
-
0035902140
-
The Hedgehog and Writ signaling pathways in cancer
-
Taipale J, Beachy PA 2001 The Hedgehog and Writ signaling pathways in cancer. Nature 411, 349-354.
-
(2001)
Nature
, vol.411
, pp. 349-354
-
-
Taipale, J.1
Beachy, P.A.2
-
35
-
-
0032528990
-
A novel variant of human Grb7 is associated with invasive esophageal carcinoma
-
Tanaka S, Mori M, Akiyoshi T et al. 1998 A novel variant of human Grb7 is associated with invasive esophageal carcinoma. Journal of Clinical Investigation 102, 821-827.
-
(1998)
Journal of Clinical Investigation
, vol.102
, pp. 821-827
-
-
Tanaka, S.1
Mori, M.2
Akiyoshi, T.3
-
36
-
-
0242290258
-
p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases
-
Ukomadu C, Dutta A 2003 p21-dependent inhibition of colon cancer cell growth by mevastatin is independent of inhibition of G1 cyclin-dependent kinases. Journal of Biological Chemistry 278, 43596-43594.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 43596-43594
-
-
Ukomadu, C.1
Dutta, A.2
-
37
-
-
0028814860
-
Different effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on sterol synthesis in various human cell types
-
van Vliet AK, van Thiel GC, Huisman RH et al. 1995 Different effects of 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors on sterol synthesis in various human cell types. Biochimica et Biophysica Acta 1254, 105-111.
-
(1995)
Biochimica et Biophysica Acta
, vol.1254
, pp. 105-111
-
-
van Vliet, A.K.1
van Thiel, G.C.2
Huisman, R.H.3
-
38
-
-
0033694305
-
Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling
-
Varnum-Finney B, Xu L, Brashem-Stein C et al. 2000 Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling. Nature Medicine 6, 1278-1281.
-
(2000)
Nature Medicine
, vol.6
, pp. 1278-1281
-
-
Varnum-Finney, B.1
Xu, L.2
Brashem-Stein, C.3
-
39
-
-
0026669469
-
p53 function and dysfunction
-
Vogelstein B, Kinzler KW 1992 p53 function and dysfunction. Cell 70, 523-526.
-
(1992)
Cell
, vol.70
, pp. 523-526
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
40
-
-
0034930259
-
HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2
-
Wachtershauser A, Akoglu B, Stein J 2001 HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2. Carcinogenesis 22, 1061-1067.
-
(2001)
Carcinogenesis
, vol.22
, pp. 1061-1067
-
-
Wachtershauser, A.1
Akoglu, B.2
Stein, J.3
-
41
-
-
0037065914
-
Statins have biphasic effects on angiogenesis
-
Weis M, Heeschen C, Glassford AJ et al. 2002 Statins have biphasic effects on angiogenesis. Circulation 105, 739-745.
-
(2002)
Circulation
, vol.105
, pp. 739-745
-
-
Weis, M.1
Heeschen, C.2
Glassford, A.J.3
-
42
-
-
10044263388
-
-
Werner M, Sacher 1, Holieneggef M 2004 Mutual amplification of apoptosis by statin-induced mitochondrial stress and doxorubicin toxicity in human rhabdomyosarcoma cells. British Journal of Pharmacology 143, 715-724,
-
Werner M, Sacher 1, Holieneggef M 2004 Mutual amplification of apoptosis by statin-induced mitochondrial stress and doxorubicin toxicity in human rhabdomyosarcoma cells. British Journal of Pharmacology 143, 715-724,
-
-
-
-
43
-
-
0034777844
-
Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin
-
Wong WW Tan MM, Xia Z et al. 2001 Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin. Clinical Cancer Research 7, 2067-2075.
-
(2001)
Clinical Cancer Research
, vol.7
, pp. 2067-2075
-
-
Wong, W.W.1
Tan, M.M.2
Xia, Z.3
-
44
-
-
33646872074
-
NANOGP8 is a retrogene expressed in cancers
-
Zhang J, Wang X, Li M et al. 2006 NANOGP8 is a retrogene expressed in cancers. FEBS Journal 273, 1723-1730.
-
(2006)
FEBS Journal
, vol.273
, pp. 1723-1730
-
-
Zhang, J.1
Wang, X.2
Li, M.3
|