-
4
-
-
0026607503
-
Cholesterol inhibition, cancer and chemotherapy
-
(1992)
Lancet
, vol.339
, pp. 1154-1156
-
-
Buchwald, H.1
-
6
-
-
13044283050
-
Alendronate mechanism of action: Geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 133-138
-
-
Fisher, J.E.1
Rogers, M.J.2
Halasy, J.M.3
Luckman, S.P.4
Hughes, D.E.5
Masarachia, P.J.6
Wesolowski, G.7
Russell, R.G.8
Rodan, G.A.9
Reszka, A.A.10
-
10
-
-
0342981862
-
The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels
-
Cholesterol and Recurrent Events Trial investigators.
-
(1996)
N. Engl. J. Med.
, vol.335
, pp. 1001-1009
-
-
Sacks, F.M.1
Pfeffer, M.A.2
Moye, L.A.3
Rouleau, J.L.4
Rutherford, J.D.5
Cole, T.G.6
Brown, L.7
Warnica, J.W.8
Arnold, J.M.9
Wun, C.C.10
Davis, B.R.11
Braunwald, E.12
-
11
-
-
10244249180
-
Safety and tolerability of cholesterol lowering agents with simvastatin during 5 years in Scandinavian simvastatin survival study
-
(1996)
Arch. Intern. Med.
, vol.156
, pp. 3085-3092
-
-
Pederson, T.R.1
Berge, K.2
Cook, T.J.3
Faergeman, O.4
Haghfelt, T.5
Kjekshus, J.6
Tatu, M.7
Mushner, T.8
Olsson, A.9
Pyoeraelae, K.10
Thorgeisson, G.11
Tobert, J.A.12
Widel, H.13
Wilhelmson, H.14
-
12
-
-
0029815533
-
Chemoprevention by pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor, of N-methyl-N-nitrosourea-induced colon carcinogenesis in F344 rats
-
(1996)
Jpn. J. Cancer Res.
, vol.87
, pp. 798-804
-
-
Narisawa, T.1
Morotomi, M.2
Fukaura, Y.3
Hasebe, M.4
Ito, M.5
Aizawa, R.6
-
13
-
-
0030498274
-
Chemopreventive efficacy of low dose of pravastatin, an HMG-CoA reductase inhibitor, on 1,2-dimethylhydrazine-induced colon carcinogenesis in ICR mice
-
(1996)
Tohoku J. Exp. Med.
, vol.180
, pp. 131-138
-
-
Narisawa, T.1
Fukaura, Y.2
Tanida, N.3
Hasebe, M.4
Ito, M.5
Aizawa, R.6
-
14
-
-
0019128183
-
Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
-
(1980)
Gut
, vol.21
, pp. 793-798
-
-
Roediger, W.E.1
-
15
-
-
0026604806
-
Effect of short-chain fatty acids on the human colonic mucosa in vitro
-
(1992)
J. Parenter. Enteral Nutr.
, vol.16
, pp. 43-48
-
-
Scheppach, W.1
Bartram, P.2
Richter, A.3
Richter, F.4
Liepold, H.5
Dusel, G.6
Hofstetter, G.7
Ruthlein, J.8
Kasper, H.9
-
24
-
-
0029145975
-
Redistribution of the CDK inhibitor p27 between different cyclin. CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation
-
(1995)
Mol. Biol. Cell
, vol.6
, pp. 1197-1213
-
-
Poon, R.Y.1
Toyoshima, H.2
Hunter, T.3
-
29
-
-
0030772026
-
Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 22199-22206
-
-
Nakano, K.1
Mizuno, T.2
Sowa, Y.3
Orita, T.4
Yoshino, T.5
Okuyama, Y.6
Fujita, T.7
Ohtani-Fujita, N.8
Matsukawa, Y.9
Tokino, T.10
Yamagishi, H.11
Oka, T.12
Nomura, H.13
Sakai, T.14
-
34
-
-
0033531269
-
Comparative effects of overexpression of p27Kip1 and p21Cip1/Waf1 on growth and differentiation in human colon carcinoma cells
-
(1999)
Oncogene
, vol.18
, pp. 103-115
-
-
Yamamoto, H.1
Soh, J.W.2
Shirin, H.3
Xing, W.Q.4
Lim, J.T.5
Yao, Y.6
Slosberg, E.7
Tomita, N.8
Schieren, I.9
Weinstein, I.B.10
-
41
-
-
0032562711
-
Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10618-10623
-
-
Lee, S.J.1
Ha, M.J.2
Lee, J.3
Nguyen, P.4
Choi, Y.H.5
Pirnia, F.6
Kang, W.K.7
Wang, X.F.8
Kim, S.J.9
Trepel, J.B.10
-
43
-
-
0029940090
-
HMG-CoA reductase mediates the biological effects of retinoic acid on human neuroblastoma cells: Lovastatin specifically targets P-glycoprotein-expressing cells
-
(1996)
Nature Med.
, vol.2
, pp. 326-333
-
-
Dimitroulakos, J.1
Yeger, H.2
-
44
-
-
0033557949
-
Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach
-
(1999)
Blood
, vol.93
, pp. 1308-1318
-
-
Dimitroulakos, J.1
Nohynek, D.2
Backway, K.L.3
Hedley, D.W.4
Yeger, H.5
Freedman, M.H.6
Minden, M.D.7
Penn, L.Z.8
-
50
-
-
0023521261
-
3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors in the treatment of hypercholesterolemia
-
(1987)
JAMA
, vol.258
, pp. 3532-3536
-
-
Hoeg, J.M.1
Brewer, H.B.2
-
53
-
-
0020660954
-
Reduction of serum cholesterol in heterozygous patients with familial hypercholesterolemia. Additive effects of compactin and cholestyramine
-
(1983)
N. Engl. J. Med.
, vol.308
, pp. 609-613
-
-
Mabuchi, H.1
Sakai, T.2
Sakai, Y.3
Yoshimura, A.4
Watanabe, A.5
Wakasugi, T.6
Koizumi, J.7
Takeda, R.8
-
55
-
-
0031671753
-
Cerivastatin in primary hyperlipidemia-a multicenter analysis of efficacy and safety
-
(1998)
Atherosclerosis
, vol.139
, Issue.SUPPL. 1
-
-
Stein, E.1
-
56
-
-
0031954530
-
Phase I study of the orally administered butyrate prodrug, tributyrin, in patients with solid tumors
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 629-634
-
-
Conley, B.A.1
Egorin, M.J.2
Tait, N.3
Rosen, D.M.4
Sausville, E.A.5
Dover, G.6
Fram, R.J.7
Van Echo, D.A.8
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