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Volumn 320, Issue 1, 2004, Pages 165-169

Depletion of membrane cholesterol causes ligand-independent activation of Fas and apoptosis

Author keywords

Apoptosis; CD95; Cholesterol; Fas; Keratinocytes; Lipid rafts

Indexed keywords

CASPASE 8; CHOLESTEROL; CHOLESTEROL OXIDASE; COMPACTIN; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FILIPIN; MEMBRANE LIPID; METHYL BETA CYCLODEXTRIN;

EID: 2942641691     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.05.145     Document Type: Article
Times cited : (119)

References (35)
  • 1
    • 0032421354 scopus 로고    scopus 로고
    • Functions of lipid rafts in biological membranes
    • Brown D.A., London E. Functions of lipid rafts in biological membranes. Annu. Rev. Cell Dev. Biol. 14:1998;111-136
    • (1998) Annu. Rev. Cell Dev. Biol. , vol.14 , pp. 111-136
    • Brown, D.A.1    London, E.2
  • 4
    • 0037959071 scopus 로고    scopus 로고
    • The state of lipid rafts: From model membranes to cells
    • Edidin M. The state of lipid rafts: from model membranes to cells. Annu. Rev. Biophys. Biomol. Struct. 32:2003;257-283
    • (2003) Annu. Rev. Biophys. Biomol. Struct. , vol.32 , pp. 257-283
    • Edidin, M.1
  • 6
    • 0037306407 scopus 로고    scopus 로고
    • The roles of membrane microdomains (rafts) in T cell activation
    • Horejsi V. The roles of membrane microdomains (rafts) in T cell activation. Immunol. Rev. 191:2003;148-164
    • (2003) Immunol. Rev. , vol.191 , pp. 148-164
    • Horejsi, V.1
  • 7
    • 0037072273 scopus 로고    scopus 로고
    • Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking
    • Pike L.J., Casey L. Cholesterol levels modulate EGF receptor-mediated signaling by altering receptor function and trafficking. Biochemistry. 41:2002;10315-10322
    • (2002) Biochemistry , vol.41 , pp. 10315-10322
    • Pike, L.J.1    Casey, L.2
  • 8
    • 0037037545 scopus 로고    scopus 로고
    • Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling
    • Arron J.R., Pewzner-Jung Y., Walsh M.C., Kobayashi T., Choi Y. Regulation of the subcellular localization of tumor necrosis factor receptor-associated factor (TRAF)2 by TRAF1 reveals mechanisms of TRAF2 signaling. J. Exp. Med. 196:2002;923-934
    • (2002) J. Exp. Med. , vol.196 , pp. 923-934
    • Arron, J.R.1    Pewzner-Jung, Y.2    Walsh, M.C.3    Kobayashi, T.4    Choi, Y.5
  • 9
    • 0036195136 scopus 로고    scopus 로고
    • An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes
    • Hueber A.O., Bernard A.M., Hérincs Z., Couzinet A., He H.T. An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytes. EMBO Rep. 3:2002;190-196
    • (2002) EMBO Rep. , vol.3 , pp. 190-196
    • Hueber, A.O.1    Bernard, A.M.2    Hérincs, Z.3    Couzinet, A.4    He, H.T.5
  • 11
    • 0038742813 scopus 로고    scopus 로고
    • Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation
    • Legler D.F., Micheau O., Doucey M.A., Bron C. Recruitment of TNF receptor 1 to lipid rafts is essential for TNFα-mediated NF-κB activation. Immunity. 18:2003;655-664
    • (2003) Immunity , vol.18 , pp. 655-664
    • Legler, D.F.1    Micheau, O.2    Doucey, M.A.3    Bron, C.4
  • 12
    • 1142287412 scopus 로고    scopus 로고
    • Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death
    • Muppidi J.R., Siegel R.M. Ligand-independent redistribution of Fas (CD95) into lipid rafts mediates clonotypic T cell death. Nat. Immunol. 5:2004;182-189
    • (2004) Nat. Immunol. , vol.5 , pp. 182-189
    • Muppidi, J.R.1    Siegel, R.M.2
  • 14
    • 0031943921 scopus 로고    scopus 로고
    • Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L
    • Aragane Y., Kulms D., Metze D., Wilkes G., Poppelmann B., Luger T.A., Schwarz T. Ultraviolet light induces apoptosis via direct activation of CD95 (Fas/APO-1) independently of its ligand CD95L. J. Cell Biol. 140:1998;171-182
    • (1998) J. Cell Biol. , vol.140 , pp. 171-182
    • Aragane, Y.1    Kulms, D.2    Metze, D.3    Wilkes, G.4    Poppelmann, B.5    Luger, T.A.6    Schwarz, T.7
  • 15
    • 0031803217 scopus 로고    scopus 로고
    • Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis
    • Caricchio R., Reap E.A., Cohen P.L. Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocyte apoptosis. J. Immunol. 161:1998;241-251
    • (1998) J. Immunol. , vol.161 , pp. 241-251
    • Caricchio, R.1    Reap, E.A.2    Cohen, P.L.3
  • 16
    • 0033583191 scopus 로고    scopus 로고
    • Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs
    • Micheau O., Solary E., Hammann A., Dimanche-Boitrel M.T. Fas ligand-independent, FADD-mediated activation of the Fas death pathway by anticancer drugs. J. Biol. Chem. 274:1999;7987-7992
    • (1999) J. Biol. Chem. , vol.274 , pp. 7987-7992
    • Micheau, O.1    Solary, E.2    Hammann, A.3    Dimanche-Boitrel, M.T.4
  • 17
    • 85047683345 scopus 로고    scopus 로고
    • Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1)
    • Kulms D., Dussmann H., Poppelmann B., Stander S., Schwarz A., Schwarz T. Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1). Cell Death Differ. 9:2002;598-608
    • (2002) Cell Death Differ. , vol.9 , pp. 598-608
    • Kulms, D.1    Dussmann, H.2    Poppelmann, B.3    Stander, S.4    Schwarz, A.5    Schwarz, T.6
  • 18
    • 0348230802 scopus 로고    scopus 로고
    • In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells
    • Bang B., Gniadecki R., Larsen J.K., Baadsgaard O., Skov L. In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells. Exp. Dermatol. 12:2003;791-798
    • (2003) Exp. Dermatol. , vol.12 , pp. 791-798
    • Bang, B.1    Gniadecki, R.2    Larsen, J.K.3    Baadsgaard, O.4    Skov, L.5
  • 19
    • 0344825072 scopus 로고    scopus 로고
    • DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation
    • Huang H.L., Fang L.W., Lu S.P., Chou C.K., Luh T.Y., Lai M.Z. DNA-damaging reagents induce apoptosis through reactive oxygen species-dependent Fas aggregation. Oncogene. 22:2003;8168-8177
    • (2003) Oncogene , vol.22 , pp. 8168-8177
    • Huang, H.L.1    Fang, L.W.2    Lu, S.P.3    Chou, C.K.4    Luh, T.Y.5    Lai, M.Z.6
  • 21
    • 0037424543 scopus 로고    scopus 로고
    • Association of the death-inducing signaling complex with microdomains after triggering through CD95/Fas. Evidence for caspase-8-ganglioside interaction in T cells
    • Garofalo T., Misasi R., Mattei V., Giammarioli A.M., Malorni W., Pontieri G.M., Pavan A., Sorice M. Association of the death-inducing signaling complex with microdomains after triggering through CD95/Fas. Evidence for caspase-8-ganglioside interaction in T cells. J. Biol. Chem. 278:2003;8309-8315
    • (2003) J. Biol. Chem. , vol.278 , pp. 8309-8315
    • Garofalo, T.1    Misasi, R.2    Mattei, V.3    Giammarioli, A.M.4    Malorni, W.5    Pontieri, G.M.6    Pavan, A.7    Sorice, M.8
  • 26
    • 0037844879 scopus 로고    scopus 로고
    • Microvillar membrane microdomains exist at physiological temperature. Role of galectin-4 as lipid raft stabilizer revealed by "superrafts"
    • Braccia A., Villani M., Immerdal L., Niels-Christiansen L.L., Nystrom B.T., Hansen G.H., Danielsen E.M. Microvillar membrane microdomains exist at physiological temperature. Role of galectin-4 as lipid raft stabilizer revealed by "superrafts" J. Biol. Chem. 278:2003;15679-15684
    • (2003) J. Biol. Chem. , vol.278 , pp. 15679-15684
    • Braccia, A.1    Villani, M.2    Immerdal, L.3    Niels-Christiansen, L.L.4    Nystrom, B.T.5    Hansen, G.H.6    Danielsen, E.M.7
  • 27
    • 0037147320 scopus 로고    scopus 로고
    • Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor
    • Chen X., Resh M.D. Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor. J. Biol. Chem. 277:2002;49631-49637
    • (2002) J. Biol. Chem. , vol.277 , pp. 49631-49637
    • Chen, X.1    Resh, M.D.2
  • 28
    • 0037166323 scopus 로고    scopus 로고
    • Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding
    • Roepstorff K., Thomsen P., Sandvig K., van Deurs B. Sequestration of epidermal growth factor receptors in non-caveolar lipid rafts inhibits ligand binding. J. Biol. Chem. 277:2002;18954-18960
    • (2002) J. Biol. Chem. , vol.277 , pp. 18954-18960
    • Roepstorff, K.1    Thomsen, P.2    Sandvig, K.3    Van Deurs, B.4
  • 29
    • 0346435104 scopus 로고    scopus 로고
    • Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects: Studies with cholesterol enantiomers
    • Westover E.J., Covey D.F., Brockman H.L., Brown R.E., Pike L.J. Cholesterol depletion results in site-specific increases in epidermal growth factor receptor phosphorylation due to membrane level effects: studies with cholesterol enantiomers. J. Biol. Chem. 278:2003;51125-51133
    • (2003) J. Biol. Chem. , vol.278 , pp. 51125-51133
    • Westover, E.J.1    Covey, D.F.2    Brockman, H.L.3    Brown, R.E.4    Pike, L.J.5
  • 30
    • 0041833749 scopus 로고    scopus 로고
    • Flotillas of lipid rafts in transit amplifying cell-like keratinocytes
    • Gniadecki R., Bang B. Flotillas of lipid rafts in transit amplifying cell-like keratinocytes. J. Invest. Dermatol. 121:2003;522-528
    • (2003) J. Invest. Dermatol. , vol.121 , pp. 522-528
    • Gniadecki, R.1    Bang, B.2
  • 31
    • 2542458153 scopus 로고    scopus 로고
    • Potential antitumor effects of statins
    • Jakobisiak M., Golab J. Potential antitumor effects of statins. Int. J. Oncol. 23:2003;1055-1069
    • (2003) Int. J. Oncol. , vol.23 , pp. 1055-1069
    • Jakobisiak, M.1    Golab, J.2
  • 32
    • 0036239832 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and the malignant cell: The statin family of drugs as triggers of tumor-specific apoptosis
    • Wong W.W., Dimitroulakos J., Minden M.D., Penn L.Z. HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis. Leukemia. 16:2002;508-519
    • (2002) Leukemia , vol.16 , pp. 508-519
    • Wong, W.W.1    Dimitroulakos, J.2    Minden, M.D.3    Penn, L.Z.4
  • 33
    • 0033557949 scopus 로고    scopus 로고
    • Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach
    • Dimitroulakos J., Nohynek D., Backway K.L., Hedley D.W., Yeger H., Freedman M.H., Minden M.D., Penn L.Z. Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: a potential therapeutic approach. Blood. 93:1999;1308-1318
    • (1999) Blood , vol.93 , pp. 1308-1318
    • Dimitroulakos, J.1    Nohynek, D.2    Backway, K.L.3    Hedley, D.W.4    Yeger, H.5    Freedman, M.H.6    Minden, M.D.7    Penn, L.Z.8
  • 34
    • 0033529171 scopus 로고    scopus 로고
    • Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase
    • Rao S., Porter D.C., Chen X., Herliczek T., Lowe M., Keyomarsi K. Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase. Proc. Natl. Acad. Sci. USA. 96:1999;7797-7802
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 7797-7802
    • Rao, S.1    Porter, D.C.2    Chen, X.3    Herliczek, T.4    Lowe, M.5    Keyomarsi, K.6
  • 35
    • 0038121035 scopus 로고    scopus 로고
    • Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses
    • Li H.Y., Appelbaum F.R., Willman C.L., Zager R.A., Banker D.E. Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood. 101:2003;3628-3634
    • (2003) Blood , vol.101 , pp. 3628-3634
    • Li, H.Y.1    Appelbaum, F.R.2    Willman, C.L.3    Zager, R.A.4    Banker, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.