Sensitivity of C3H10T1/2 cells to radiation-induced killing and neoplastic transformation as a function of cell cycle

International Journal of Radiation Biology

Volumn 69, Issue 1, 1996, Pages 57-66

  Pazzaglia, S ^a   Saran, A ^a   Pariset, L ^a   Rebessi, S ^a   Di Majo, V ^a   Coppola, M ^a   Covelli, V ^a  

^a ENEA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL CYCLE; CELL KILLING; CELL TRANSFORMATION; CONTROLLED STUDY; FISSION NEUTRON; MOUSE; PRIORITY JOURNAL; X IRRADIATION; ANIMAL; C3H MOUSE; CELL AGING; CELL DEATH; CELL DIVISION; COMPARATIVE STUDY; CYTOLOGY; PHYSIOLOGY; RADIATION DOSE; RADIATION EXPOSURE;

ANIMALIA; RICE STRIPE VIRUS;

ANIMALS; CELL AGING; CELL CYCLE; CELL DEATH; CELL DIVISION; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; MICE; MICE, INBRED C3H; RADIATION TOLERANCE;

EID: 0029664582     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530096146183     Document Type: Article

References (47)

1. AHNSTROM, G. and EHRENBERG, L., 1980, The nature of the target in the biological action of ionizing radiations. Advances in Biology and Medical Physics, 17, 129-172.
2. BALCER-KUBICZEK, E. K. and HARRISON G. H., 1991, Lack of dose rate modification (0.0049 vs 0.12Gy/min) of fission-neutron-induced neoplastic transformation in C3H10T1/2 cells. International Journal of Radiation Biology, 59, 1017-1026.
3. BALCER-KUBICZEK, E. K., HARRISON, G. H., ZEMAN, G. H., MATTSON, P. J. and KUNSKA, A., 1988, Lack of inverse dose-rate effect on fission neutron induced transformation of C3H10T1/2 cells. International Journal of Radiation Biology, 54, 531-536.
4. BERTRAM, J. S., 1977, Effects of serum concentration on the expression of carcinogen-induced transformation in the C3H10T1/2 CL8 cell line. Cancer Research, 37, 514-523.
5. BREIMER, L. H., 1988, Ionizing radiation-induced mutagenesis. British Journal of Cancer, 57, 6-18.
6. BRENNER, D. J. and HALL, E. J., 1990, The inverse dose-rate effect for oncogenic transformation by neutrons and charged particles: a plausible interpretation consistent with published data. International Journal of Radiation Biology, 58, 745-758.
7. BURKI, H. J., 1980, Ionizing radiation-induced 6-thioguanine-resistant clones in synchronous CHO cells. Radiation Research, 81, 76-84.
8. 2/M-phase age interval. International Journal of Radiation Biology, 62, 191-199.
9. ELKIND, M. M., 1991, Enhanced neoplastic transformation due to protracted exposures of fission-spectrum neutrons: a biophysical model. International Journal of Radiation Biology, 59, 1467-1475.
10. HALL, E. J., 1969, Radiobiological measurements with 14-MeV neutrons. British Journal of Radiology, 42, 805-813.
11. HAN, A. and ELKIND, M. M., 1979, Transformation of mouse C3H10T1/2 cells by single and fractionated doses of X-rays and fission-spectrum neutrons. Cancer Research, 39, 123-130.
12. HIEBER, L., PONSEL, G., ROOS, H., FEEN, S., FROMKE, E. and KELLERER, A. M., 1987, Absence of dose-rate effect in the transformation of C3H10T1/2 cells by α-particles. International Journal of Radiation Biology, 52, 859-869.
13. HILL, C. K., 1989, Is the induction of neoplastic transformation by radiation dependent upon the quality and dose rate? Institute of Physical and Chemical Research, 83, 31-35.
14. HILL, C. K., BUONAGURO, F. M., MYERS, C. P. and ELKIND, M. M., 1982, Fission-spectrum neutrons at reduced dose rate enhance neoplastic transformation. Nature (London), 298, 67-68.
15. HILL, C. K., CARNES, B. A., HAN, A. and ELKIND, M. M., 1985, Neoplastic transformation is enhanced by multiple low doses of fission-spectrum neutrons. Radiation Research, 102, 404-410.
16. HILL, C. K., HAN, A. and ELKIND, M. M., 1984, Fission-spectrum neutrons at low dose rate enhance neoplastic transformation in the linear, low dose region (0-10cGy). International Journal of Radiation Biology, 46, 11-14.
17. ILIAKIS, G. and NÜSSE, M., 1983a, Evidence that repair and expression of potentially lethal damage causes the variations in survival after X-irradiation observed through the cell cycle in Ehrlich ascites tumor cells. Radiation Research, 95, 87-107.
18. 1/S-border and mitosis in the fixation of potentially lethal damage. Radiation Research, 22, 201-207.
19. JONES, C. A., SEDITA, B. A., HILL, C. K. and ELKIND, M. M., 1989, Influence of dose rate on the transformation of Syrian hamster embryo cells by fission-spectrum neutrons. In: Low Dose Radiation. Edited by: K. F. Baverstock and J. W. Sthather (London, Taylor & Francis), pp. 539-546.
20. JOSTES, R. F., BUSHNELL, K. M. and DEWEY, W. C., 1980, X-ray induction of 8-azaguanina-resistant mutants in synchronous Chinese hamster ovary cells. Radiation Research, 83, 146-161.
21. KASTAN, M. B., ONYEKWERE, O., SIDRANSKY, D., VOGESTEIN, B. and CRAIG, R. W., 1991, Participation of p53 protein in the cellular response to DNA damage. Cancer Research, 51, 6304-6311.
22. MILLER, R. C., BRENNER, D. J., GEARD, C. R., KOMATSU, K., MARINO, S. A. and HALL, E. J., 1988, Oncogenic transformation by fractionated doses of neutrons. Radiation Research, 114, 589-597.
23. MILLER, R. C., GEARD, C. R., GEARD, M. J. and HALL, E. J., 1992, Cell-cycle-dependent radiation-induced oncogenic transformation of C3H10T1/2 cells. Radiation Research, 130, 129-133.
24. MILLER, R. C., RANDERS-PEHRSON, G., HIEBER, L., MARINO, S. A., RICHARDS, M. and HALL, E. J., 1993, The inverse dose-rate effect for oncogenic transformation by charged particles is dependent on linear energy transfer. Radiation Research, 133, 360-364.
25. OTTO, F., 1990, DAPI staining of fixed cells for high-resolution flow cytometry of nuclear DNA. In: Flow Cytometry. Edited by Z. Darzynkiewicz and H. A. Crissman (London, Academic), pp. 105-110.
26. PIHET, P., COPPOLA, M., LONCOL, T., DI MAJO, V. and MENZEL, H. G., 1994, Microdosimetry study of radiobiological facilities of the RSV-TAPIRO reactor. Radiation Protection Dosimetry, 52, 409-414.
27. REDPATH, J. L., HILL, C. K., JONES, C. A. and SUN, C., 1990, Fission-neutron-induced expression of a tumor-associated antigen in human cell hybrids (HeLa x skin fibroblast): evidence for increased expression at low dose rate. International Journal of Radiation Biology, 58, 673-680.
28. 1 phases of the cell cycle. Radiation Research, 121, 206-211.
29. 1 phase are not hypersensitive cell cycle phases for neoplastic transformation of HeLa x skin fibroblast human hybrid cells induced by fission-spectrum neutrons. Radiation Research, 141, 37-43.
30. REZNIKOFF, C. A., BRANKOW, D. W. and HEIDELBERGER, C., 1973a, Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Research, 33, 3231-3238.
31. REZNIKOFF, C. A., BERTRAM, J. S., BRANKOW, D. W. and HEIDELBERGER, C., 1973b, Quantitative and qualitative studies of chemical transformation of clonal C3H mouse embryo cells sensitive to post-confluence inhibition of cell division. Cancer Research, 33, 3239-3249.
32. ROSSI, H. H. ad KELLERER, A. M., 1986, The dose rate dependence of oncogenic transformation in the linear, low-dose region (0-10 cGy). International Journal of Radiation Biology, 50, 353-361.
33. ROOTS, R. and OKADA, S., 1972, Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds. International Journal of Radiation Biology, 21, 329-342.
34. SARAN, A., PAZZAGLIA, S., COPPOLA, M., REBESSI, S., DI MAJO, V., GARAVINI, M. and COVELLI, V., 1991, Absence of dose-fractionation effect on neoplastic transformation induced by fission-spectrum neutrons in C3H10T1/2 cells. Radiation Research, 126, 343-348.
35. SARAN, A., PAZZAGLIA, S., PARISET, L., REBESSI, S., BROERSE, J. J., ZOETELIEF, J., DI MAJO, V., COPPOLA, M. and COVELLI, V., 1994, Neoplastic transformation of C3H10T1/2 cells: a study with fractionated doses of monoenergetic neutrons. Radiation Research, 138, 246-251.
36. SINCLAIR, W. K., 1968, Radiation survival in synchronous and asynchronous Chinese hamster cells in vitro. In: Biophysical Aspects of Radiation Quality (Vienna, IAEA), pp. 33-54.
37. SINCLAIR, W. K., 1969, Dependence of radiosensitivity upon cell age. In: Proceedings of the Carmel Conference on Time and Dose Relationships in Radiation Biology as Applied to Radiotherapy. BNL Report 50203 (C-57) (Brookhaven National Laboratory, Upton).
38. SINCLAIR, W. K. and MORTON, R. A., 1966, X-ray sensitivity during the cell generation cycle of cultured Chinese hamster cells. Radiation Research, 29, 450-474.
39. 60Co γ-rays. International Journal of Radiation Biology, 63, 475-481.
40. TERASIMA, T. and TOLMACH, L. J., 1963, X-ray sensitivity and DNA synthesis in synchronous population of HeLa cells. Science, 140, 490-492.
41. WARD, J. F., 1985, Biochemistry of DNA lesions. Radiation Research, 104, (suppl. 8), 103-111.
42. WATANABE, M., SUZUKI, N., SAWADA, S. and NIKAIDO, O., 1984, Repair of lethal, mutagenic and transforming damage induced by X-rays in golden hamster embryo cells. Carcinogenesis, 5, 1293-1299.
43. WEINERT, T. A. and HARTWELL, L. H., 1988, The RAD9 controls the cell cycle response to DNA damage in Saccharomyces cerevisiae. Science, 241, 317-322.
44. WHEELER, K. and WIEROWSKI, J., 1983, DNA accessibility: a determinant of mammalian cell differentiation? Radiation Research, 93, 312-318.
45. WINANS, L. F., DEWEY, W. C. and Dettor, C. M., 1972, Repair of sublethal and potentially lethal X-ray damage in synchronous Chinese hamster cells. Radiation Research, 52, 333-351.
46. WITHERS, H. R., MASON, K., REID, B. O., DUBRAVSKY, H. T., BROWN, B. W. and SMATHERS, J. B., 1974, Response of mouse intestine to neutrons and gamma rays in relation to dose fractionation and division cycle. Cancer, 34, 39-47.
47. YANG, T. C., CRAISE, L. M., MEI, M. T. and TOBIAS, C. A., 1986, Dose protraction with low and high LET radiation on neoplastic transformation. Advances in Space Research, 6, 137-147.