Tandem enzyme-catalysed reduction/cis-dihydroxylation of 2,2,2-trifluoroacetophenone: Chemoenzymatic routes to new enantiopure phenol and benzylic alcohol reagents

Journal of Chemical Technology and Biotechnology

Volumn 82, Issue 12, 2007, Pages 1072-1081

  Boyd, Derek R ^a   Sharma, Narain D ^a   Ljubez, Vera ^a   Malone, John F ^a   Allen, Christopher C R ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

Author keywords

Enzymatic ketone reduction arene cis dihydroxylation; Tandem dehydrogenase dioxygenase activity

Indexed keywords

ARENE CIS-DIHYDROXYLATION; DIOXYGENASE ACTIVITY; ENZYMATIC KETONE REDUCTION; TANDEM DEHYDROGENASE;

BACTERIA; CATALYSTS; HYDROXYLATION; KETONES; SYNTHESIS (CHEMICAL); TOLUENE;

BIOCHEMISTRY;

2,2,2 TRIFLUOROACETOPHENONE; ACETOPHENONE DERIVATIVE; BENZYL ALCOHOL DERIVATIVE; DIOXYGENASE; KETONE; KETONE DERIVATIVE; OXIDOREDUCTASE; PHENOL DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON; REAGENT; TOLUENE DIOXYGENASE; UNCLASSIFIED DRUG;

BACTERIA; BIOCHEMISTRY; CATALYSTS; HYDROXYLATION; KETONES; SYNTHESIS (CHEMICAL); TOLUENE;

ARTICLE; BACTERIAL METABOLISM; BACTERIUM MUTANT; BIOTECHNOLOGICAL PROCEDURES; BIOTRANSFORMATION; CATALYSIS; CHIRALITY; DIHYDROXYLATION; ENANTIOSELECTIVITY; ENZYME MECHANISM; NONHUMAN; PSEUDOMONAS PUTIDA; REACTION ANALYSIS; REDUCTION; STEREOCHEMISTRY;

PSEUDOMONAS PUTIDA;

EID: 36348963092     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.1686     Document Type: Article

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