Spontaneous and radiation-induced apoptosis in colorectal carcinoma cells with different intrinsic radiosensitivities: Survivin as a radioresistance factor

International Journal of Radiation Oncology Biology Physics

Volumn 55, Issue 5, 2003, Pages 1341-1347

  Rödel, Claus ^a,b   Haas, Joachim ^a   Groth, Anke ^a   Grabenbauer, Gerhard G ^a   Sauer, Rolf ^a   Rödel, Franz ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

Apoptosis; Colorectal cancer; Radiosensitivity; Survivin

Indexed keywords

CARCINOGENS; PROTEINS; RNA; TUMORS;

TUMOR RESPONSE;

RADIOTHERAPY;

4',6 DIAMIDINO 2 PHENYLINDOLE; MESSENGER RNA; SURVIVIN;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER RESISTANCE; CARCINOMA CELL; COLONY FORMING UNIT; COLORECTAL CARCINOMA; CONTROLLED STUDY; CORRELATION ANALYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; NICK END LABELING; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RADIATION EXPOSURE; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; WESTERN BLOTTING;

EID: 0037376549     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(02)04618-7     Document Type: Article

References (34)

1. Meyn R.E., Stephens L.C., Ang K.K., et al. Heterogeneity in the development of apoptosis in irradiated murine tumors of different histologies. Int J Radiat Biol Phys. 64:1993;583-591.
2. Meyn R.E., Stephens L.C., Milas L. Programmed cell death and radioresistance. Cancer Metastasis Rev. 15:1996;119-131.
3. Rödel C., Grabenbauer G.G., Papadopoulos T., et al. Apoptosis as a cellular predictor for histopathologic response to neoadjuvant radiochemotherapy in patients with rectal cancer. Int J Radiat Oncol Biol Phys. 52:2002;294-303.
4. Ambrosini G., Adida C., Altieri D.C. A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma. Nat Med. 3:1997;917-921.
5. Monzo M., Rosell R., Felip E., et al. A novel anti-apoptosis gene Re-expression of survivin messenger RNA as a prognostic marker in non-small-cell lung cancer. J Clin Oncol. 17:1999;2100-2104.
6. Satoh K., Kaneko K., Hirota M., et al. Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumor. Cancer. 92:2001;271-278.
7. Lu C.D., Altieri D.C., Tanigawa N. Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas. Cancer Res. 58:1998;1808-1812.
8. Tanaka K., Iwamoto S., Gon G., et al. Expression of survivin and its relationship to loss of apoptosis in breast carcinomas. Clin Cancer Res. 6:2000;127-134.
9. Kato J., Kuwabara Y., Mitani M., et al. Expression of survivin in esophageal cancer Correlation with prognosis and response to chemotherapy. Int J Cancer. 95:2001;92-95.
10. Kappler M., Köhler T., Kampf C., et al. Increased survivin transcript levels An independent negative predictor of survival in soft tissue sarcoma patients. Int J Cancer. 95:2001;360-363.
11. Kawasaki H., Altieri D.C., Lu C.D., at al. Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Res. 58:1998;5071-5074.
12. Sarela A.I., Macadam R.C.A., Farmery S.M., et al. Expression of the antiapoptosis gene, survivin, predicts death from recurrent colorectal cancer. Gut. 46:2000;645-650.
13. Sauer R., Fietkau R., Wittekind C., et al. Adjuvant versus neoadjuvant radiochemotherapy for locally advanced rectal cancer A progress report of a phase-III randomized trial (protocol CAO/ARO/AIO-94). Strahlenther Onkol. 177:2001;173-181.
14. Rödel F., Hoffmann J., Grabenbauer G.G., et al. High survivin expression is associated with reduced apoptosis in rectal cancer and may predict disease-free survival after preoperative radiochemotherapy and surgical resection. Strahlenther Onkol. 78:2002;426-435.
15. Leibovitz A., Stinson J.C., McCombs W.B., et al. Classification of human colorectal adenocarcinoma cell lines. Cancer Res. 36:1976;4562-4569.
16. Rodrigues N.R., Rowan A., Smith M.E., et al. p53 mutations in colorectal cancer. Proc Natl Acad Sci U S A. 87:1990;7555-7559.
17. Dexter D.L., Barbosa J.A., Calabresi P. N,N-dimethylformamide-induced alteration of cell culture characteristics and loss of tumorigenicity in cultured human colon carcinoma cells. Cancer Res. 39:1979;1020-1025.
18. O'Connor P.M., Jackman J., Bae I., et al. Characterization of the p53 tumor suppressor pathway in cell lines of the National Cancer Institute anticancer drug screen and correlations with the growth-inhibitory potency of 123 anticancer agents. Cancer Res. 57:1997;4285-4300.
19. Leith J.H., Faulkner L.A., Papa G., et al. In vitro radiation survival parameters of human colon tumor cells. Int J Radiat Oncol Biol Phys. 20:1991;203-206.
20. Abe T., Sakaguchi Y., Ohno S., et al. Apoptosis and p53 overexpression in human rectal cancer; relationship with response to hyperthermo-chemo-radiotherapy. Anticancer Res. 21:2001;2115-2120.
21. Adell G.C.E., Zhang H., Evertsson S., et al. Apoptosis in rectal carcinoma. Prognosis and recurrence after preoperative radiotherapy. Cancer. 91:2001;1870-1875.
22. Rich T.A., Sinicrope F., Stephens C., et al. Downstaging of T3 rectal cancer after preoperative infusional chemoradiation is correlated with spontaneous apoptosis index, and bcl-2 staining. [Abstract] Int J Radiat Oncol Biol Phys. 36:(Suppl. 1):1996;259.
23. Scott N., Hale A., Deakin M., et al. A histopathological assessment of response of rectal adenocarcinoma to combination chemo-radiotherapy Relationship to apoptotic activity, p53 and bcl-2 expression. Eur J Surg Oncol. 24:1998;169-173.
24. Tannapfel A., Nüßlein S., Fietkau R., et al. Apoptosis, proliferation, Bax, Bcl-2, and p53 status prior to, and after preoperative radiochemotherapy for locally advanced rectal cancer. Int J Radiat Oncol Biol Phys. 41:1998;585-591.
25. Sakakura C., Koide K., Wakasa T., et al. Analysis of histological therapeutic effect, apoptosis rate and p53 status after combined treatment with radiation, hyperthermia and 5-fluorouracil suppositories for advanced rectal cancer. Br J Cancer. 77:1998;159-166.
26. Sirzen F., Zhivotovsky B., Nilsson A., et al. Spontaneous and radiation-induced apoptosis in lung carcinoma cells with different intrinsic radiosensitivities. Anticancer Res. 18:1998;695-700.
27. Clem R.J., Miller L.K. Control of programmed cell death by the baculovirus genes p53 and iap. Mol Cell Biol. 14:1994;5212-5222.
28. Altieri D.C. The molecular basis and potential role of survivin in cancer diagnosis and therapy. Trend Mol Med. 7:2001;542-547.
29. Velculescu V.E., Madden S.L., Zhang L., et al. Analysis of human transcriptomes. Nat Genet. 23:1999;387-388.
30. Asanuma K., Yajima T., et al. Survivin as a radioresistance factor in pancreatic cancer. Jpn J Cancer Res. 91:2000;1204-1209.
31. Tamm I., Wang Y., Sausville E., et al. IAP-family protein survivin inhibits caspase activity, and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res. 58:1998;5315-5320.
32. Hoffman W.H., Biade S., Zilfou J.T., et al. Transcriptional repression of anti-apoptotic survivin gene by wild type p53. J Biol Chem. 277:2002;3247-3257.
33. Mirza A., McGuirk M., Hockenberry T.N., et al. Human survivin is negatively regulated by wild-type p53 and participates in p53-dependent apoptotic pathway. Oncogene. 21:2002;2613-2622.
34. Olie R.A., Simoes-Wüst A.P., Baumann B., et al. A novel antisense oligonucleotide targeting surviving expression induces apoptosis and sensitizes lung cancer cells to chemotherapy. Cancer Res. 60:2000;2805-2809.