Inhibition of Survivin and Aurora B Kinase Sensitizes Mesothelioma Cells by Enhancing Mitotic Arrests

International Journal of Radiation Oncology Biology Physics

Volumn 67, Issue 5, 2007, Pages 1519-1525

  Kim, Kwang Woon ^a   Mutter, Robert W ^a   Willey, Christopher D ^a   Subhawong, Ty K ^b   Shinohara, Eric T ^c   Albert, Jeffrey M ^a   Ling, Geng ^a   Cao, Carolyn ^a   Gi, Young Jin ^a   Lu, Bo ^a  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Aurora B kinase; Mesothelioma; Radiation; Survivin; ZM447439

Indexed keywords

BIOASSAY; ENZYME INHIBITION; FLOW CYTOMETRY; GENETIC ENGINEERING; OLIGONUCLEOTIDES; ONCOLOGY;

AURORA B KINASE; MESOTHELIOMA; SURVIVIN; ZM447439;

CELLS;

ANTISENSE OLIGONUCLEOTIDE; AURORA B KINASE; CASPASE; HISTONE H3; N [4 [6 METHOXY 7 (3 MORPHOLINOPROPOXY) 4 QUINAZOLINYLAMINO]PHENYL]BENZAMIDE; SURVIVIN;

ARTICLE; CANCER RADIOTHERAPY; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL SURVIVAL; CLONOGENIC ASSAY; CONTROLLED STUDY; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MESOTHELIOMA; MITOSIS INHIBITION; MULTINUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIVITY; WESTERN BLOTTING;

BENZAMIDES; CASPASE 3; CELL SURVIVAL; G2 PHASE; HISTONES; HUMANS; MESOTHELIOMA; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; NEOPLASM PROTEINS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; QUINAZOLINES; RADIATION TOLERANCE; UP-REGULATION;

EID: 33947535689     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.12.018     Document Type: Article

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