Microarray analysis of gene expression profile of multidrug resistance in pancreatic cancer

Chinese Medical Journal

Volumn 120, Issue 20, 2007, Pages 1743-1752

  Zhao, Yu Pei ^a   Chen, Ge ^a   Feng, Bin ^a   Zhang, Tai Ping ^a   Ma, En Ling ^a   Wu, Yuan De ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

Author keywords

Chemoresistance prediction; Differential expressed genes; Microarray; Multidrug resistance; Pancreatic cancer

Indexed keywords

DOXORUBICIN; FLUOROURACIL; GEMCITABINE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL ADHESION; CELL CYCLE; CHEMOSENSITIVITY; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA MICROARRAY; DOWN REGULATION; EPIGENETICS; EXPRESSED SEQUENCE TAG; GENE EXPRESSION PROFILING; GENETIC ASSOCIATION; GENETIC LINKAGE; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MULTIDRUG RESISTANCE; NUCLEOTIDE SEQUENCE; PANCREAS CANCER; PANCREAS CARCINOMA; PREDICTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUPPORT VECTOR MACHINE; UNINDEXED SEQUENCE; UPREGULATION; VALIDATION PROCESS; WESTERN BLOTTING;

EID: 36148996841     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200710020-00003     Document Type: Article

References (41)

1. Warshaw AL, Fernandez-del Castillo C. Pancreatic carcinoma N Engl J Med 1992 13; 326: 455-465.
2. Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, et al. Cancer statistics 2005. CA Cancer J Clin 2005; 55:10-30.
3. Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA, et al. Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg 1997; 226: 248-257.
4. Ahmad NA, Lewis JD, Ginsberg GG, Haller DG, Morris JB, Williams. NN, et al. Long term, survival after pancreatic resection for pancreatic adenocarcinom. Am J Gastroenterol 2001; 96:2609-2615.
5. Stefańska B, Arciemiuk M, Bontemps-Gracz MM, Dzieduszycka M, Kupiec A, Martelli S, et al. Synthesis and biological evaluation of 2,7-Dihydro-3H-benzo[dé,h]cinnoline-3,7-dione derivatives, a novel group of anticancer agents active on a multidrug resistant cell. line. Bioorg-Med Chem 2003; 11: 561-572.
6. Sonneveld P, Segeren CM. Current, perspective changing concepts in multiple myeloma: from conventional chemotherapy to high-dose treatment. Eur J Cancer 2003; 39: 9-18.
7. Kommann M, Danenberg KD, Arber N, Beger HG, Danenberg PV, Korc M. Inhibition of cyclin D1 expression in human pancreatic cancer cells is' associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes. Cancer Res 1999, 59: 3505-3511.
8. Broxterman HJ, Lankelma J, Pinedo. HM. How to probe clinical tumour samples for P-glycoprotein and multidrug resistance-associated protein. Eur J Cancer 1996; 32: 1024-1033.
9. Debouck C, Goodfellow PN. DNA microarrays in drug discovery and development. Nat Genet 1999; 21: 48-50.
10. Plumb JA, Milroy R, Kaye SB. Effects of the pH dependence of 3-(4,5-dimethylthiazol- .2-yi)-2,5-diphenyl-tetrazolium bromide-formazan absorption on chemosensitivity determined by a novel tetrazolium-based assay. Cancer Res 1989; 49: 4435-4440.
11. Zhan F, Hardin J, Kordsmeier B, Bumm K, Zheng M, Tian E, et al. Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells. Blood 2002; 99: 1745-1758.
12. Bubner B, Baldwin IT. Use of real-time PCR for determining copy number and zygosity in transgenic plants. Plant Cell Rep 2004; 23: 263-271.
13. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, et al. Gene ontology: Tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 2000; 25: 25-29.
14. Jarzab B, Wiench M, Fujarewicz K. Gene expression profile of papillary thyroid cancer: sources of variability and diagnostic implications. Cancer Res 2005; 65: 1587-1597.
15. Brandt-R, Grützmann R, Bauer A, Jesnowski R, Ringel J, Löhr M, et al. DNA microarray analysis of pancreatic malignancies. Pancreatology 2004; 4: 587-597.
16. Sawiris GP, Sherman-Baust CA, Becker KG, Cheadle C, Teichberg D, Morin PJ. Development of a highly specialized cDNA array for the study and diagnosis of epithelial ovarian cancer. Cancer Res 2002; 62: 2923-2928.
17. Liu B, Staren ED, Iwamura T, Appert HE, Howard JM. Mechanisms of taxotere-related drug resistance in pancreatic carcinoma. J Surg Res 2001; 99: 179-186.
18. Wang W, Cassidy J, O'Brien V, Ryan KM, Collie-Duguid E. Mechanistic and predictive profiling of 5-Fluorouracil resistance in human cancer cells. Cancer Res 2004; 64: 8167-8176.
19. Maehara S, Tanaka S, Shimada M, Shirabe K, Saito Y, Takahashi K, et al. Selenoprotein P, as a predictor for evaluating gemicitabine resistance in human pancreatic cancer cells. Int J Cancer 2004; 112: 184-189.
20. Kong Q, Lillehei KO. Antioxidant inhibitors for cancer therapy. Med Hypotheses 1998; 51: 405-409.
21. Beckett GJ, Arthur JR. Selenium and endocrine systems. J Endocrinol 2005; 184: 455-465.
22. Hough CD, Cho KR, Zonderman AB, Schwartz DR, Morin PJ. Coordinately up-regulated genes in ovarian cancer. Cancer Res 2001; 61: 3869-3876.
23. Debatin AK. Activation of apoptosis pathways by anticancer treatment. Toxicol Lett 2000; 112: 41-48.
24. Watts GS, Futscher BW, Isett P, Gleason-Guzman M, Kunkel MW, Salmon SE. cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways. J Pharmacol Exp Ther 2001; 299:434-441.
25. Mao C, Xu F, Szulc ZM, Bielawska A, Galadari SH, Obeid LM. Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide. J Biol Chem 2001; 276: 26577-26588.
26. Simstein R, Burow M, Parker A, Weldon C, Beckman B. Apoptosis, chemoresistance, and breast cancer: insights from the MCF-7 cell model system. Exp Biol Med (Maywood) 2003; 228: 995-1003.
27. Itoh M, Kitano T, Watanabe M, Kondo T, Yabu T, Taguchi Y, et al. Possible role of Ceramide as an indicator of chemoresistance: Decrease of the Ceramide content via activation of glucósylceramide synthase and sphingomyelin synthase in chemoresistant. leukemia Clin Cancer Res 2003; 8: 415-423.
28. Thiebault K, Mazelin L, Pays L, Llambi F, Joly MO, Seoazec JY, et al. The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment Proc Natl Acad Sci USA 2003; 100: 4173-4178.
29. Cook BD, Dynek JN, Chang W, Shostak G, Smith S. Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres. Mol Cell Biol 200; 22: 332-342.
30. Monz D, Munnia. A, Comtesse N, Fischer U, Steudel WI, Feiden W, et al. Novel tankyrase-related gene detected with meningioma-specific sera. Clin Cancer Res 2001; 7: 113-119.
31. Lyons RJ, Deane R, Lynch DK, Ye ZS, Sanderson GM, Eyre HJ, et al. Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14. J Biol Chem 2001; 276: 17172-17180.
32. Bertin J, Wang L, Guo Y, Jacobson MD, Poyet JL, Srinivasula SM, et al. CARD11 and CARD14 are novel caspase recruitment domain (CARD)/ membrane-associated guanylate kinase (MAGUK) family members that interact with BCL10 and activate NF-kappa B. J Biol Chem 2001; 276: 11877-11882.
33. Martin-Lluesma S, Stucke VM, Nigg EA, Role Of Hec1 in spindle checkpoint signaling and kinetochore reruitment of Mad1/Mad2. Science 2002;297: 2267-2270.
34. Einarson MB, Cukierman E, Compton DA, Golemis EA. Human enhancer btf invasion-cluster, a coiled-coil protein required for passage through mitosis. Mol Cell Biol 2004; 24: 3957-3971.
35. Tirnauer JS, Canman JC, Salmon ED, Mitchison TJ. EB1 targets to kinetochores with attached, polymerizing microtubules. Mol Biol Cell 2002; 13: 4308-4316.
36. Kaneta Y, Kagami Y, Katagiri T, Tsunoda T, Jin-nai I, Taguchi H, et al. Prediction of sensitivity to STI571 among, chronic myeloid leukemia patients by genome-wide cDNA microarray analysis. Jpn J Cancer Res 2002; 93: 849-856.
37. Brown MP, Grundy WN, Lin D, Cristianini N, Sugnet CW, Furey TS, et al. knowledge-based analysis of microarray gene expression data by using support vector machines. Proc Natl Acad Sci USA 2000; 97: 262-267.
38. Vapnik VN. Statistical learning theory. New York: Wiley Press; 1998.
39. Wang HJ, Zheng CX, Li Y, Zhu HF, Yan XG. Application of support vector machines to classification of blood cells. J Biomed Eng 2003; 20: 484-487.
40. Lee Y, Lee CK. Classification of multiple cancer types by multicategory support vector machines using gene expression data. Bioinformatics 2003; 19: 1132-1139.
41. Staunton JE, Slonim. DK, Coller HA, Tamayo P, Angelo MJ, Park J, et al. Chemosensitivity prediction by transcriptional profiling. Proc Natl Acad Sci USA 2001; 989: 10787-10792.