A caspase-3-cleaved fragment of the glial glutamate transporter EAAT2 is sumoylated and targeted to promyelocytic leukemia nuclear bodies in mutant SOD1-linked amyotrophic lateral sclerosis

Journal of Biological Chemistry

Volumn 282, Issue 44, 2007, Pages 32480-32490

  Gibb, Stuart L ^a,b   Boston Howes, William ^b   Lavina, Zeno S ^c   Gustincich, Stefano ^c   Brown Jr , Robert H ^b   Pasinelli, Piera ^a   Trotti, Davide ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c SISSA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CYTOTOXICITY; DISEASES; MUTAGENESIS; NEUROLOGY; OXIDATIVE STRESS; PROTEINS;

ASTROCYTES; CENTRAL NERVOUS SYSTEM; SPINAL CORD;

ENZYME ACTIVITY;

CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; EXCITATORY AMINO ACID TRANSPORTER 2;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CELL CULTURE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MOUSE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SPINAL CORD;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ASTROCYTES; CASPASE 3; CELL NUCLEUS STRUCTURES; EXCITATORY AMINO ACID TRANSPORTER 2; HUMANS; HUNTINGTON DISEASE; IMMUNOPRECIPITATION; INTRANUCLEAR INCLUSION BODIES; MICE; MICE, TRANSGENIC; MOLECULAR WEIGHT; PROTEIN STRUCTURE, TERTIARY; RATS; SPINAL CORD; SUMO-1 PROTEIN; SUPEROXIDE DISMUTASE;

MUS;

EID: 36148957860     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704314200     Document Type: Article

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