Oral treatment with ACCUTANE® does not increase measures of anhedonia or depression in rats

Neurotoxicology and Teratology

Volumn 29, Issue 6, 2007, Pages 642-651

  Ferguson, Sherry A ^a   Cisneros, F Javier ^b   Hanig, Joseph P ^c   Berry, Kimberly J ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b CHARLES RIVER LABORATORIES   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

ACCUTANE; Anhedonia; Depression; Forced swim test; Isotretinoin; Retinoic acid

Indexed keywords

ISOTRETINOIN; RETINOIC ACID; SACCHARIN; SOYBEAN OIL;

ANHEDONIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEPRESSION; DOSE TIME EFFECT RELATION; DRUG DOSE COMPARISON; FEMALE; FORCED SWIMMING TEST; MALE; NONHUMAN; PRIORITY JOURNAL; SUICIDE;

ADMINISTRATION, ORAL; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BEHAVIOR, ANIMAL; DEPRESSION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRINKING; EATING; FEMALE; FOOD PREFERENCES; ISOTRETINOIN; MALE; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; SWIMMING; TERATOGENS; TIME FACTORS;

GLYCINE MAX; RATTUS; RODENTIA;

EID: 36049012533     PISSN: 08920362     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ntt.2007.09.003     Document Type: Article

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