Isotretinoin therapy and depression - Evidence for an association

Irish Journal of Psychological Medicine

Volumn 15, Issue 2, 1998, Pages 58-60

  Byrne, Alan ^a   Costello, Morgan ^b   Greene, Elaine ^c   Zibin, Terry ^d  

^a Naas General Hospital   (Ireland)

^b St Loman's Hospital   (Ireland)

^c E Hlth Bd Mental Handicap Service   (Ireland)

^d Alberta Hospital   (Canada)

Author keywords

Aggression; Agitation; Depression; Isotretinoin

Indexed keywords

FLUOXETINE; ISOTRETINOIN; TRAZODONE;

ACNE; ADULT; AGITATION; ARTICLE; CASE REPORT; DEPRESSION; DISEASE ASSOCIATION; DRUG OVERDOSE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IRRITABILITY; MALE; MOOD; RATING SCALE; RETINOL DEFICIENCY; SUICIDAL BEHAVIOR;

EID: 0031847002     PISSN: 07909667     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0790966700003530     Document Type: Article

References (15)

1. Ginsberg H, Rubenstein A, Brown WV. Medical complications of isotretinoin. Clin Dermatol 1986; 4(1): 183-9.
2. Bonnetblanc JM, Hugon AJ, Dumas M. Intracranial hypertension with etretinate. Lancet 1983; ii: 974.
3. Marsden JR. Lipid metabolism and retinoid therapy. Pharmacol Ther 1975; 40: 55-65.
4. Roenigk HH Jr. Liver toxicity of retinoid therapy. J Am Acad Dermatol 1988; 19: 199-208.
5. McIvor A. Fatal toxic epidermal necrolysis associated with etretinate. BMJ 1992; 304: 548.
6. David M, Hodak E, Lowe N. Adverse effects of retinoids. Medical Toxicology 1988; 3: 273-88.
7. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23: 56-62.
8. Scheineman PL, Peck GL, Rubinow DR, DiGiovanna JJ. Acute depression from isotretinoin. J Am Acad Derm 1990; 1112-4.
9. Saurat H. Side-effects of systemic retinoids and their clinical management. J Am Acad Derm 1992; 27: S23-S28.
10. Mandell HG. Fat soluble vitamins. In: Goodman LS and Gilman A, eds. The Pharmacological Basis of Therapeutics. New York: MacMillan, 1975: 1570-7.
11. Bravard P, Krug M, Rzeznick JC. Isotretinoin et depression, soyons vigilantes. Nouveau Dermatologie 1993; 12: 215.
12. Gatti S, Serri F. Acute depression from isotretinoin. J Am Acad Derm 1991; 25: 132.
13. Peck GL, DiGiovanna JJ, Rubinow DR. Acute depression from isotretinoin, reply. J Am Acad Derm 1991; 25: 132.
14. MacDonald Hull S, Cunliffe WJ, Hughes BR. Treatment of the depressed and dysmorphophobic acne patient. Clinical and Experimental Dermatology 1991; 16: 210-11.
15. Goulden V, Layton AM, and Cunliffe, WJ. Long-term treatment with isotretinoin as a treatment for acne vulgaris. Br J Derm 1994; 131: 360-3.