13-cis retinoic acid (Accutane) suppresses hippocampal cell survival in mice

Annals of the New York Academy of Sciences

Volumn 1021, Issue , 2004, Pages 436-440

  Sakai, Yasuo ^a   Crandall, James E ^a   Brodsky, Jacob ^b   McCaffery, Peter ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

BrdU; Dentate gyrus; Depression; Meninges; Neurogenesis; RALDH2; Subgranular zone; Vitamin A

Indexed keywords

ISOTRETINOIN;

ANIMAL CELL; ANIMAL EXPERIMENT; BRAIN ATROPHY; CELL LOSS; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; DEPRESSION; EXPERIMENTAL MODEL; EXPOSURE; HIPPOCAMPUS; HYPOTHESIS; MENINX; MOUSE; NERVE CELL; NONHUMAN;

ANIMALIA;

EID: 3042710988     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1308.059     Document Type: Conference Paper

References (15)

1. WYSOWSKI, D.K., J. SWANN & A. VEGA. 2002. Use of isotretinoin (Accutane) in the United States: rapid increase from 1992 through 2000. J. Am. Acad. Dermatol. 46: 505-509.
2. MCCAFFERY, P. & U.C. DRAGER. 2000. Regulation of retinoic acid signaling in the embryonic nervous system: a master differentiation factor. Cytokine Growth Factor Rev. 11: 233-249.
3. HULL, P.R. & C. DEMKIW-BARTEL. 2000. Isotretinoin use in acne: prospective evaluation of adverse events. J. Cutan. Med. Surg. 4: 66-70.
4. SCHEINMAN, P.L., et al. 1990. Acute depression from isotretinoin. J. Am. Acad. Dermatol. 22: 1112-1114.
5. JOSEFSON, D. 1998. Acne drug is linked to severe depression. Br. Med. J. 316: 723.
6. SHELINE, Y.I., et al. 1996. Hippocampal atrophy in recurrent major depression. Proc. Natl. Acad. Sci. USA 93: 3908-3913.
7. MALBERG, J.E., et al. 2000. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 20: 9104-9110.
8. KEMPERMANN, G. 2002. Regulation of adult hippocampal neurogenesis - implications for novel theories of major depression. Bipolar Disord. 4: 17-33.
9. VYTHILINGAM, M., et al. 2002. Childhood trauma associated with smaller hippocampal volume in women with major depression. Am. J. Psychiatry 159: 2072-2080.
10. MISNER, D.L., et al. 2001. Vitamin A deprivation results in reversible loss of hippocampal long-term synaptic plasticity. Proc. Natl. Acad. Sci. USA 98: 11714-11719.
11. ROSSANT, J., et al. 1991. Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis. Genes Dev. 5: 1333-1344.
12. MILLER, M.W. & R.S. NOWAKOWSKI. 1998. Use of bromodeoxyuridine- immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system. Brain Res. 457: 44-52.
13. KUHN, H.G., H. DICKINSON-ANSON & F.H. GAGE. 1996. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16: 2027-2033.
14. KEMPERMANN, G., H.G. KUHN & F.H. GAGE. 1997. Genetic influence on neurogenesis in the dentate gyrus of adult mice. Proc. Natl. Acad. Sci. USA 94: 10409-10414.
15. CRANDALL, J., et al. 2004. 13-Cis-retinoic acid suppresses hippocampal cell division and hippocampal-dependent learning in mice. Proc. Natl. Acad. Sci. USA 101: 5111-5116.