The excision mechanism in reverse transcriptase: Pyrophosphate leaving and fingers opening are uncoupled events with the analogues AZT and d4T

Journal of Physical Chemistry B

Volumn 111, Issue 41, 2007, Pages 12032-12039

  Carvalho, Alexandra T P ^a   Fernandes, Pedro A ^a   Ramos, Maria J ^a  

^a UNIVERSITY OF PORTO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTER SIMULATION; ENZYME INHIBITION; HYDROGEN; MOLECULAR DYNAMICS; NUCLEOTIDES; PHOSPHATES; SUBSTRATES;

ANTIRETROVIRALS; EXCISION MECHANISM; PYROPHOSPHATE; REVERSE TRANSCRIPTASE;

ENZYME ACTIVITY;

EID: 35948998054     PISSN: 15206106     EISSN: None     Source Type: Journal    
DOI: 10.1021/jp0746594     Document Type: Article

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