Nonnucleoside Inhibitor Binding Affects the Interactions of the Fingers Subdomain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase with DNA

Journal of Virology

Volumn 78, Issue 7, 2004, Pages 3387-3397

  Peletskaya, Elena N ^a   Kogon, Alex A ^b   Tuske, Steven ^c   Arnold, Edward ^c   Hughes, Stephen H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,6 DIFLUOROBENZYL) 2 (2,6 DIFLUOROPHENYL) 4 METHOXYBENZIMIDAZOLE; CYSTEINE; DEOXYNUCLEOSIDE TRIPHOSPHATE; DNA; DOUBLE STRANDED DNA; NUCLEOSIDE TRIPHOSPHATE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG; CROSS LINKING REAGENT; RECOMBINANT PROTEIN;

ARTICLE; CONFORMATIONAL TRANSITION; CROSS LINKING; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN DOMAIN; VIRUS MUTANT; AMINO ACID SUBSTITUTION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; METABOLISM; PHOTOCHEMISTRY; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SUBSTITUTION; BINDING SITES; CROSS-LINKING REAGENTS; CYSTEINE; DNA; ESCHERICHIA COLI; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; MODELS, MOLECULAR; PHOTOCHEMISTRY; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE INHIBITORS;

EID: 1842562404     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.7.3387-3397.2004     Document Type: Article

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