Ancient exaptation of a CORE-SINE retroposon into a highly conserved mammalian neuronal enhancer of the proopiomelanocortin gene

PLoS Genetics

Volumn 3, Issue 10, 2007, Pages 1813-1826

  Santangelo, Andrea M ^a   De Souza, Flávio S J ^a   Franchini, Lucía F ^a   Bumaschny, Viviana F ^a   Low, Malcolm J ^b,c   Rubinstein, Marcelo ^a,b,d,e  

^a INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^b Center for the Study of Weight Regulation and Associated Disorders   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^e CENTRO DE ESTUDIOS CIENTÍFICOS CECS   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

PROOPIOMELANOCORTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; COMPUTER MODEL; EMBRYO; ENHANCER REGION; FEMALE; GENE EXPRESSION; GENETIC CONSERVATION; GENETIC DATABASE; GENETIC LINE; GENOME ANALYSIS; HYPOTHALAMUS; INTRON; MAMMALIAN GENETICS; MARSUPIAL; MOLECULAR EVOLUTION; MONOTREMATE; MOUSE; MULTIGENE FAMILY; NEWBORN; NONHUMAN; PHYSICAL ANTHROPOLOGY; PLACENTA; REPORTER GENE; RETROPOSON; SHORT INTERSPERSED REPEAT; TRANSPOSON; VERTEBRATE;

ANIMALS; BASE SEQUENCE; COMPUTATIONAL BIOLOGY; CONSENSUS SEQUENCE; CONSERVED SEQUENCE; EMBRYONIC DEVELOPMENT; ENHANCER ELEMENTS (GENETICS); EVOLUTION, MOLECULAR; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOMICS; MAMMALS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NEURONS; OPOSSUMS; PALEONTOLOGY; PRO-OPIOMELANOCORTIN; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; SHORT INTERSPERSED NUCLEOTIDE ELEMENTS;

DIDELPHIDAE; EUTHERIA; GNATHOSTOMATA (VERTEBRATE); MAMMALIA; METATHERIA; MONOTREMATA; MUS MUSCULUS; VERTEBRATA;

EID: 35948981635     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0030166     Document Type: Article

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