Molecular mechanism of Mitomycin C-dependent caspase-8 regulation: Implications for apoptosis and synergism with interferon-α signalling

Apoptosis

Volumn 12, Issue 12, 2007, Pages 2259-2270

  Liedtke, Christian ^a   Lambertz, Daniela ^a   Schnepel, Nadine ^a   Trautwein, Christian ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

C jun AP1; Caspase 8; Chemotherapy; Gene transcription; Hepatocellular carcinoma; Hepatoma cells

Indexed keywords

ALPHA INTERFERON; CASPASE 8; LUCIFERASE; MESSENGER RNA; MITOMYCIN C; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVITY; GENETIC TRANSCRIPTION; HEPATOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION INITIATION; UPREGULATION;

APOPTOSIS; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; DRUG SYNERGISM; ENZYME ACTIVATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTERFERON-ALPHA; MITOMYCIN; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; RESPONSE ELEMENTS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION, GENETIC;

ADENOVIRIDAE;

EID: 35948952340     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-007-0145-x     Document Type: Article

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