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Volumn 14, Issue 10, 1998, Pages 869-883

Non-linear optimization of biochemical pathways: Applications to metabolic engineering and parameter estimation

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOCHEMISTRY; BIOENGINEERING; COMPUTER PROGRAM; EXPERIMENTAL MODEL; INDUSTRY; INTERNET; KINETICS; METABOLISM; PARAMETER; PRIORITY JOURNAL; SIMULATION;

EID: 0032406131     PISSN: 13674803     EISSN: 13674811     Source Type: Journal    
DOI: 10.1093/bioinformatics/14.10.869     Document Type: Article
Times cited : (577)

References (93)
  • 1
    • 0002651837 scopus 로고
    • An overview of evolutionary algorithms for parameter optimization
    • Bäck, T. and Schwefel, H.-P. (1993) An overview of evolutionary algorithms for parameter optimization. Evol. Comput., 1, 1-23.
    • (1993) Evol. Comput. , vol.1 , pp. 1-23
    • Bäck, T.1    Schwefel, H.-P.2
  • 3
    • 0030921134 scopus 로고    scopus 로고
    • TRUST: A deterministic algorithm for global optimisation
    • Barhen, J., Protopopescu, V. and Reister, D. (1997) TRUST: a deterministic algorithm for global optimisation. Science, 276, 1094-1097.
    • (1997) Science , vol.276 , pp. 1094-1097
    • Barhen, J.1    Protopopescu, V.2    Reister, D.3
  • 4
    • 0026719686 scopus 로고
    • Global analysis of biochemical and biophysical data
    • Beechem, J.M. (1992) Global analysis of biochemical and biophysical data. Methods Enzymol., 210, 37-54.
    • (1992) Methods Enzymol. , vol.210 , pp. 37-54
    • Beechem, J.M.1
  • 5
    • 0031966808 scopus 로고    scopus 로고
    • Reconstruction of amino acid biosynthesis pathways from the complete genome sequence
    • Bono, H., Ogata, H., Goto, S. and Kanehisa, M. (1998) Reconstruction of amino acid biosynthesis pathways from the complete genome sequence. Genome Res., 8, 203-210.
    • (1998) Genome Res. , vol.8 , pp. 203-210
    • Bono, H.1    Ogata, H.2    Goto, S.3    Kanehisa, M.4
  • 6
    • 0028267221 scopus 로고
    • Computer simulated evolution of a network of cell-signaling molecules
    • Bray, D. and Lay, S. (1994) Computer simulated evolution of a network of cell-signaling molecules. Biophys. J., 66, 972-977.
    • (1994) Biophys. J. , vol.66 , pp. 972-977
    • Bray, D.1    Lay, S.2
  • 7
    • 26444603536 scopus 로고    scopus 로고
    • Current Biology, London
    • Brenner, S. (1997) Loose Ends. Current Biology, London.
    • (1997) Loose Ends
    • Brenner, S.1
  • 8
    • 0000732463 scopus 로고
    • A limited memory algorithm for bound constrained optimisation
    • Byrd, R.H., Lu, P., Nocedal, J. and Zhu, C. (1995) A limited memory algorithm for bound constrained optimisation. SIAM J. Sci. Comput., 16, 1190-1208.
    • (1995) SIAM J. Sci. Comput. , vol.16 , pp. 1190-1208
    • Byrd, R.H.1    Lu, P.2    Nocedal, J.3    Zhu, C.4
  • 10
    • 0027352238 scopus 로고
    • Cellular and metabolic engineering: An overview
    • Cameron, D.C. and Tong, I. (1993) Cellular and metabolic engineering: an overview. Appl. Biochem. Biotechnol., 38, 105-140.
    • (1993) Appl. Biochem. Biotechnol. , vol.38 , pp. 105-140
    • Cameron, D.C.1    Tong, I.2
  • 11
    • 0028747898 scopus 로고
    • Algorithm 739: A software package for unconstrained optimization using tensor methods
    • Chow, T., Eskow, F. and Schanbel, R. (1994) Algorithm 739: A software package for unconstrained optimization using tensor methods. ACM Trans. Math. Softw., 20, 518-530.
    • (1994) ACM Trans. Math. Softw. , vol.20 , pp. 518-530
    • Chow, T.1    Eskow, F.2    Schanbel, R.3
  • 12
    • 50549159930 scopus 로고
    • The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations
    • Cleland, W.W. (1963) The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations. Biochim. Biophys. Acta. 67, 104-137.
    • (1963) Biochim. Biophys. Acta , vol.67 , pp. 104-137
    • Cleland, W.W.1
  • 13
    • 0018735516 scopus 로고
    • Statistical analysis of enzyme kinetic data
    • Cleland, W.W. (1979) Statistical analysis of enzyme kinetic data. Methods Enzymol., 63, 103-138.
    • (1979) Methods Enzymol. , vol.63 , pp. 103-138
    • Cleland, W.W.1
  • 14
    • 0023416976 scopus 로고
    • Minimizing multimodal functions of continuous variables with the 'simulated annealing' algorithm
    • Corana, A., Marchesi, M., Martini, C. and Ridella, S. (1987) Minimizing multimodal functions of continuous variables with the 'simulated annealing' algorithm. ACM Trans. Math. Softw., 13, 262-280.
    • (1987) ACM Trans. Math. Softw. , vol.13 , pp. 262-280
    • Corana, A.1    Marchesi, M.2    Martini, C.3    Ridella, S.4
  • 15
    • 0026023024 scopus 로고
    • METAMODEL A program for modeling and control analysis of metabolic pathways on the IBM pc and compatibles
    • Cornish-Bowden, A. and Hofmeyr, J.H. (1991) METAMODEL A program for modeling and control analysis of metabolic pathways on the IBM pc and compatibles. Comput. Applic. Biosci., 7, 89-93.
    • (1991) Comput. Applic. Biosci. , vol.7 , pp. 89-93
    • Cornish-Bowden, A.1    Hofmeyr, J.H.2
  • 16
    • 0029585284 scopus 로고
    • Strategies for manipulating metabolic fluxes in biotechnology
    • Cornish-Bowden, A., Hofmeyr, J.-H.S. and Cárdenas, M.L. (1995) Strategies for manipulating metabolic fluxes in biotechnology. Bioorg. Chem., 23, 439-449.
    • (1995) Bioorg. Chem. , vol.23 , pp. 439-449
    • Cornish-Bowden, A.1    Hofmeyr, J.-H.S.2    Cárdenas, M.L.3
  • 17
    • 26444584705 scopus 로고
    • Numerical methods for simulation and optimization
    • Hemker, H.C. and Hess, B. (eds), North-Holland Publishing Co., Amsterdam
    • Curtis, A.R. and Chance, E.M. (1972) Numerical methods for simulation and optimization. In Hemker, H.C. and Hess, B. (eds), Analysis and Simulation of Biochemical Systems. North-Holland Publishing Co., Amsterdam, pp. 39-57.
    • (1972) Analysis and Simulation of Biochemical Systems , pp. 39-57
    • Curtis, A.R.1    Chance, E.M.2
  • 19
    • 0031888036 scopus 로고    scopus 로고
    • High throughput protein characterization by automated reverse-phase chromatography electrospray tandem mass spectrometry
    • Ducret, A., van Oostveen, I., Eng, J.K., Yates, J.R. and Aebersold, R. (1998) High throughput protein characterization by automated reverse-phase chromatography electrospray tandem mass spectrometry. Protein Sci., 7, 706-719.
    • (1998) Protein Sci. , vol.7 , pp. 706-719
    • Ducret, A.1    Van Oostveen, I.2    Eng, J.K.3    Yates, J.R.4    Aebersold, R.5
  • 21
    • 0021636975 scopus 로고
    • Regression analysis of nonlinear Arrhenius plots: An empirical model and a computer program
    • Duggleby, R.G. (1984) Regression analysis of nonlinear Arrhenius plots: an empirical model and a computer program. Comput. Biol. Med., 14, 447-445.
    • (1984) Comput. Biol. Med. , vol.14 , pp. 447-1445
    • Duggleby, R.G.1
  • 22
    • 0021842628 scopus 로고
    • Estimation of the initial velocity of enzyme-catalysed reactions by non-linear regression analysis of progress curves
    • Duggleby, R.G. (1985) Estimation of the initial velocity of enzyme-catalysed reactions by non-linear regression analysis of progress curves. Biochem. J., 228, 55-60.
    • (1985) Biochem. J. , vol.228 , pp. 55-60
    • Duggleby, R.G.1
  • 23
    • 0029073341 scopus 로고
    • MIST: A user-friendly metabolic simulator
    • Ehlde, M. and Zacchi, G. (1995) MIST: a user-friendly metabolic simulator. Comput. Applic. Biosci., 11, 201-207.
    • (1995) Comput. Applic. Biosci. , vol.11 , pp. 201-207
    • Ehlde, M.1    Zacchi, G.2
  • 24
    • 0027415226 scopus 로고
    • Cellular automata approaches to biological modeling
    • Ermentrout, G.B. and Edelstein-Keshet, L. (1993) Cellular automata approaches to biological modeling. J. Theor. Biol., 160, 97-133.
    • (1993) J. Theor. Biol. , vol.160 , pp. 97-133
    • Ermentrout, G.B.1    Edelstein-Keshet, L.2
  • 25
    • 0032069707 scopus 로고    scopus 로고
    • Global optimization in parameter estimation of nonlinear algebraic models via the error-in-variables approach
    • Esposito, W.R. and Floudas, C.A. (1998) Global optimization in parameter estimation of nonlinear algebraic models via the error-in-variables approach. Ind. Eng. Chem. Res., 37, 1841-1858.
    • (1998) Ind. Eng. Chem. Res. , vol.37 , pp. 1841-1858
    • Esposito, W.R.1    Floudas, C.A.2
  • 27
    • 0026802334 scopus 로고
    • Metabolic control analysis a survey of its theoretical and experimental development
    • Fell, D.A. (1992) Metabolic control analysis a survey of its theoretical and experimental development. Biochem. J., 286, 313-330.
    • (1992) Biochem. J. , vol.286 , pp. 313-330
    • Fell, D.A.1
  • 34
    • 0027335729 scopus 로고
    • Numerical integration of rate equations by computer
    • Frieden, C. (1993) Numerical integration of rate equations by computer. Trends Biochem. Sci., 18, 58-60.
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 58-60
    • Frieden, C.1
  • 35
    • 0025400371 scopus 로고
    • Fermentation pathway kinetics and metabolic flux control in suspended and immobilized Saccharomyces cerevisae
    • Galazzo, J.L. and Bailey, J.E. (1990) Fermentation pathway kinetics and metabolic flux control in suspended and immobilized Saccharomyces cerevisae. Enzyme Microb. Technol., 12, 162-172.
    • (1990) Enzyme Microb. Technol. , vol.12 , pp. 162-172
    • Galazzo, J.L.1    Bailey, J.E.2
  • 37
    • 0342476373 scopus 로고
    • Computer modeling of metabolic pathways
    • Garfinkel, D. (1981) Computer modeling of metabolic pathways. Trends Biochem. Sci., 6, 69-71.
    • (1981) Trends Biochem. Sci. , vol.6 , pp. 69-71
    • Garfinkel, D.1
  • 39
    • 0029096741 scopus 로고
    • Genetic-algorithm selection of a regulatory structure that directs flux in a simple metabolic model
    • Gilman, A. and Ross, J. (1995) Genetic-algorithm selection of a regulatory structure that directs flux in a simple metabolic model. Biophys. J., 69, 1321-1333.
    • (1995) Biophys. J. , vol.69 , pp. 1321-1333
    • Gilman, A.1    Ross, J.2
  • 41
    • 0001237594 scopus 로고
    • Maximisation by quadratic hill-climbing
    • Goldfeld, S.M., Quant, R.E. and Trotter, H.F. (1966) Maximisation by quadratic hill-climbing. Econometrica, 34, 541-555.
    • (1966) Econometrica , vol.34 , pp. 541-555
    • Goldfeld, S.M.1    Quant, R.E.2    Trotter, H.F.3
  • 44
    • 0015989446 scopus 로고
    • A linear steady-state treatment of enzymatic chains. General properties, control and effector strength
    • Heinrich, R. and Rapoport, T.A. (1974) A linear steady-state treatment of enzymatic chains. General properties, control and effector strength. Eur. J. Biochem., 42, 89-95.
    • (1974) Eur. J. Biochem. , vol.42 , pp. 89-95
    • Heinrich, R.1    Rapoport, T.A.2
  • 47
    • 0023497923 scopus 로고
    • A theoretical approach to the evolution and structural design of enzymatic networks. Linear enzymatic chains, branched pathways and glycolysis of erythrocytes
    • Heinrich, R., Holzhutter, H.G. and Schuster, S. (1987) A theoretical approach to the evolution and structural design of enzymatic networks. Linear enzymatic chains, branched pathways and glycolysis of erythrocytes. Bull. Math. Biol., 49, 539-595.
    • (1987) Bull. Math. Biol. , vol.49 , pp. 539-595
    • Heinrich, R.1    Holzhutter, H.G.2    Schuster, S.3
  • 48
    • 0031030714 scopus 로고    scopus 로고
    • Theoretical approaches to the evolutionary optimization of glycolysis: Thermodynamic and kinetic constraints
    • Heinrich, R., Montero, F., Klipp, E., Waddell, T.G. and Meléndez-Hevia, H. (1997) Theoretical approaches to the evolutionary optimization of glycolysis: thermodynamic and kinetic constraints. Eur. J. Biochem., 243, 191-201.
    • (1997) Eur. J. Biochem. , vol.243 , pp. 191-201
    • Heinrich, R.1    Montero, F.2    Klipp, E.3    Waddell, T.G.4    Meléndez-Hevia, H.5
  • 49
    • 0028673743 scopus 로고
    • Applying bifurcation theory to enzyme kinetics
    • Hocker, C.G. (1994) Applying bifurcation theory to enzyme kinetics. Methods Enzymol., 240, 781-816.
    • (1994) Methods Enzymol. , vol.240 , pp. 781-816
    • Hocker, C.G.1
  • 50
    • 0022640661 scopus 로고
    • Steady-state modeling of metabolic pathways. A guide for the prospective simulator
    • Hofmeyr, J.H.S. (1986) Steady-state modeling of metabolic pathways. A guide for the prospective simulator. Comput. Applic. Biosci., 2, 5-11.
    • (1986) Comput. Applic. Biosci. , vol.2 , pp. 5-11
    • Hofmeyr, J.H.S.1
  • 51
    • 0030800564 scopus 로고    scopus 로고
    • The reversible Hill equation: How to incorporate cooperative enzymes into metabolic models
    • Hofmeyr, J.-H.S. and Cornish-Bowden, A. (1997) The reversible Hill equation: how to incorporate cooperative enzymes into metabolic models. Comput. Applic. Biosci., 13, 377-385.
    • (1997) Comput. Applic. Biosci. , vol.13 , pp. 377-385
    • Hofmeyr, J.-H.S.1    Cornish-Bowden, A.2
  • 53
    • 0025348364 scopus 로고
    • SIMFIT: A microcomputer software-toolkit for modelistic studies in biochemistry
    • Holzhütter, H.G. and Colosimo, A. (1990) SIMFIT: a microcomputer software-toolkit for modelistic studies in biochemistry. Comput. Applic. Biosci., 6, 23-28.
    • (1990) Comput. Applic. Biosci. , vol.6 , pp. 23-28
    • Holzhütter, H.G.1    Colosimo, A.2
  • 54
    • 84938447945 scopus 로고
    • 'Direct search' solution of numerical and statistical problems
    • Hooke, R. and Jeeves, T.A. (1961) 'Direct search' solution of numerical and statistical problems. J. Assoc. Comput. Mach., 8, 212-229.
    • (1961) J. Assoc. Comput. Mach. , vol.8 , pp. 212-229
    • Hooke, R.1    Jeeves, T.A.2
  • 55
    • 0026486367 scopus 로고
    • Why, when and how biochemists should use least squares
    • Johnson, M.L. (1992) Why, when and how biochemists should use least squares. Anal. Biochem., 206, 215-225.
    • (1992) Anal. Biochem. , vol.206 , pp. 215-225
    • Johnson, M.L.1
  • 56
    • 0026718393 scopus 로고
    • Parameter estimation by least-squares methods
    • Johnson, M.L. and Faunt, L.M. (1992) Parameter estimation by least-squares methods. Methods Enzymol., 210, 1-37.
    • (1992) Methods Enzymol. , vol.210 , pp. 1-37
    • Johnson, M.L.1    Faunt, L.M.2
  • 58
    • 0030340124 scopus 로고    scopus 로고
    • HinCyc: A knowledge base of the complete genome and metabolic pathways of H. influenzae
    • States, D.J., Agarwal, P., Gaasterland, T., Hunter, L. and Smith, R. (eds), AAAI Press, Menlo Park, CA
    • Karp, P.D., Ouzounis, C. and Paley, S. (1996) HinCyc: a knowledge base of the complete genome and metabolic pathways of H. influenzae. In States, D.J., Agarwal, P., Gaasterland, T., Hunter, L. and Smith, R. (eds), Proceedings of the Fourth International Conference on Intelligent Systems for Molecular Biology. AAAI Press, Menlo Park, CA, pp. 116-124.
    • (1996) Proceedings of the Fourth International Conference on Intelligent Systems for Molecular Biology , pp. 116-124
    • Karp, P.D.1    Ouzounis, C.2    Paley, S.3
  • 59
    • 0028840869 scopus 로고
    • GMP Good Modelling Practice: An essential component of good manufacturing practice
    • Kell, D.B. and Sonnleitner, B. (1995) GMP Good Modelling Practice: an essential component of good manufacturing practice. Trends Biotechnol., 13, 481-492.
    • (1995) Trends Biotechnol. , vol.13 , pp. 481-492
    • Kell, D.B.1    Sonnleitner, B.2
  • 60
    • 0022457536 scopus 로고
    • Towards a rational approach to the optimization of flux in microbial biotransformations
    • Kell, D.B. and Westerhoff, H.V. (1986) Towards a rational approach to the optimization of flux in microbial biotransformations. Trends Biotechnol., 4, 137-142.
    • (1986) Trends Biotechnol. , vol.4 , pp. 137-142
    • Kell, D.B.1    Westerhoff, H.V.2
  • 61
    • 0014683898 scopus 로고
    • Stochastic method for the simulation of biochemical systems on a digital computer
    • Kibby, M.R. (1969) Stochastic method for the simulation of biochemical systems on a digital computer. Nature, 222, 298-299.
    • (1969) Nature , vol.222 , pp. 298-299
    • Kibby, M.R.1
  • 62
    • 26444479778 scopus 로고
    • Optimization by simulated annealing
    • Kirkpatrick, S., Gelatt, C.D. and Vecchi, M.P. (1983) Optimization by simulated annealing. Science, 220, 671-680.
    • (1983) Science , vol.220 , pp. 671-680
    • Kirkpatrick, S.1    Gelatt, C.D.2    Vecchi, M.P.3
  • 63
    • 0028566137 scopus 로고
    • Evolutionary optimization of enzyme kinetic parameters: Effect of constraints
    • Klipp, E. and Heinrich, R. (1994) Evolutionary optimization of enzyme kinetic parameters: effect of constraints. J. Theor. Biol., 171, 309-323.
    • (1994) J. Theor. Biol. , vol.171 , pp. 309-323
    • Klipp, E.1    Heinrich, R.2
  • 64
    • 0031543435 scopus 로고    scopus 로고
    • Directed evolution of enzyme catalysts
    • Kuchner, O. and Arnold, F.H. (1997) Directed evolution of enzyme catalysts. Trends Biotechnol., 15, 523-530.
    • (1997) Trends Biotechnol. , vol.15 , pp. 523-530
    • Kuchner, O.1    Arnold, F.H.2
  • 65
    • 0029902679 scopus 로고    scopus 로고
    • Program DYNAFIT for the analysis of enzyme kinetic data: Application to HIV proteinase
    • Kuzmic, P. (1996) Program DYNAFIT for the analysis of enzyme kinetic data: application to HIV proteinase. Anal. Biochem., 237, 260-273.
    • (1996) Anal. Biochem. , vol.237 , pp. 260-273
    • Kuzmic, P.1
  • 66
    • 0000873069 scopus 로고
    • A method for the solution of certain nonlinear problems in least squares
    • Levenberg, K. (1944) A method for the solution of certain nonlinear problems in least squares. Q. Appl. Math., 2, 164-168.
    • (1944) Q. Appl. Math. , vol.2 , pp. 164-168
    • Levenberg, K.1
  • 67
    • 10544256600 scopus 로고    scopus 로고
    • Expression monitoring by hybridization to high-density oligonucleotide arrays
    • Lockhart, D.J. et al. (1996) Expression monitoring by hybridization to high-density oligonucleotide arrays. Nature Biotechnol., 14, 1675-1680.
    • (1996) Nature Biotechnol. , vol.14 , pp. 1675-1680
    • Lockhart, D.J.1
  • 68
    • 0019199635 scopus 로고
    • Analysis of progress curves. Rate law of pyruvate kinase type I from Escherichia coli
    • Markus, M., Plesser, T., Boiteux, A., Hess, B. and Malcovati, M. (1980) Analysis of progress curves. Rate law of pyruvate kinase type I from Escherichia coli. Biochem. J., 189, 421-433.
    • (1980) Biochem. J. , vol.189 , pp. 421-433
    • Markus, M.1    Plesser, T.2    Boiteux, A.3    Hess, B.4    Malcovati, M.5
  • 69
    • 0000169232 scopus 로고
    • An algorithm for least squares estimation of nonlinear parameters
    • Marquardt, D.W. (1963) An algorithm for least squares estimation of nonlinear parameters. SIAM J., 11, 431-441.
    • (1963) SIAM J. , vol.11 , pp. 431-441
    • Marquardt, D.W.1
  • 70
    • 0027370376 scopus 로고
    • GEPASI: A software package for modelling the dynamics, steady states and control of biochemical and other systems
    • Mendes, P. (1993) GEPASI: a software package for modelling the dynamics, steady states and control of biochemical and other systems. Comput. Applic. Biosci., 9, 563-571.
    • (1993) Comput. Applic. Biosci. , vol.9 , pp. 563-571
    • Mendes, P.1
  • 71
    • 0030921160 scopus 로고    scopus 로고
    • Biochemistry by numbers: Simulation of biochemical pathways with Gepasi 3
    • Mendes, P. (1997) Biochemistry by numbers: simulation of biochemical pathways with Gepasi 3. Trends Biochem. Sci., 22, 361-363.
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 361-363
    • Mendes, P.1
  • 72
    • 0037555766 scopus 로고    scopus 로고
    • Computer simulation of biochemical kinetics
    • Westerhoff, H.V., Snoep, J.L., Sluse, F.E., Wijker, J.E. and Kholodenko, B.N. (eds), BioThermoKinetics Press, Amsterdam
    • Mendes, P. and Kell, D.B. (1996) Computer simulation of biochemical kinetics. In Westerhoff, H.V., Snoep, J.L., Sluse, F.E., Wijker, J.E. and Kholodenko, B.N. (eds), BioThermoKinetics of the Living Cell. BioThermoKinetics Press, Amsterdam, pp. 254-257.
    • (1996) BioThermoKinetics of the Living Cell , pp. 254-257
    • Mendes, P.1    Kell, D.B.2
  • 73
    • 0031023665 scopus 로고    scopus 로고
    • Making cells work metabolic engineering for everyone
    • Mendes, P. and Kell, D.B. (1997) Making cells work metabolic engineering for everyone. Trends Biotechnol., 15, 6-7.
    • (1997) Trends Biotechnol. , vol.15 , pp. 6-7
    • Mendes, P.1    Kell, D.B.2
  • 74
    • 0011967874 scopus 로고
    • Metabolic channelling in organized enzyme systems: Experiments and models
    • Mendes, P., Kell, D.B. and Welch, G.R. (1995) Metabolic channelling in organized enzyme systems: experiments and models. Adv. Mol. Cell. Biol., 12, 1-19.
    • (1995) Adv. Mol. Cell. Biol. , vol.12 , pp. 1-19
    • Mendes, P.1    Kell, D.B.2    Welch, G.R.3
  • 76
    • 0021481124 scopus 로고
    • Newton-type minimization via the Lanczos method
    • Nash, S.G. (1984) Newton-type minimization via the Lanczos method. SIAM J. Numer. Anal., 21, 770-788.
    • (1984) SIAM J. Numer. Anal. , vol.21 , pp. 770-788
    • Nash, S.G.1
  • 77
    • 0000238336 scopus 로고
    • A simplex method for function minimization
    • Nelder, J.A. and Mead, R. (1965) A simplex method for function minimization. Comput. J., 7, 308-313.
    • (1965) Comput. J. , vol.7 , pp. 308-313
    • Nelder, J.A.1    Mead, R.2
  • 80
    • 0027178664 scopus 로고
    • SCAMP: A general-purpose simulator and metabolic control analysis program
    • Sauro, H.M. (1993) SCAMP: a general-purpose simulator and metabolic control analysis program. Comput. Applic. Biosci., 9, 441-450.
    • (1993) Comput. Applic. Biosci. , vol.9 , pp. 441-450
    • Sauro, H.M.1
  • 81
    • 0026516223 scopus 로고
    • Network analysis of intermediary metabolism using linear optimisation. I. Development of mathematical formalism
    • Savinell, J.M. and Palsson, B.O. (1992) Network analysis of intermediary metabolism using linear optimisation. I. Development of mathematical formalism. J. Theor. Biol., 154, 421-454.
    • (1992) J. Theor. Biol. , vol.154 , pp. 421-454
    • Savinell, J.M.1    Palsson, B.O.2
  • 82
    • 0023662013 scopus 로고
    • Time hierarchy in enzymatic reaction chains resulting from optimality principles
    • Schuster, S. and Heinrich, R. (1987) Time hierarchy in enzymatic reaction chains resulting from optimality principles. J. Theor. Biol., 129, 189-209.
    • (1987) J. Theor. Biol. , vol.129 , pp. 189-209
    • Schuster, S.1    Heinrich, R.2
  • 83
    • 0001112639 scopus 로고
    • Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks. I. Theoretical analysis
    • Schuster, S. and Heinrich, R. (1991) Minimization of intermediate concentrations as a suggested optimality principle for biochemical networks. I. Theoretical analysis. J. Math. Biol., 29, 425-442.
    • (1991) J. Math. Biol. , vol.29 , pp. 425-442
    • Schuster, S.1    Heinrich, R.2
  • 84
    • 0343488601 scopus 로고    scopus 로고
    • A reconstruction of the metabolism of Methanococcus jannaschii from sequence data
    • Selkov, E., Maltsev, N., Olsen, G.J., Overbeek, R. and Whitman, W.B. (1997) A reconstruction of the metabolism of Methanococcus jannaschii from sequence data. Gene, 197, GC11- GC26.
    • (1997) Gene , vol.197
    • Selkov, E.1    Maltsev, N.2    Olsen, G.J.3    Overbeek, R.4    Whitman, W.B.5
  • 86
    • 0026719689 scopus 로고
    • Analysis of residuals: Criteria for determining goodness-of-fit
    • Straume, M. and Johnson, M.L. (1992) Analysis of residuals: criteria for determining goodness-of-fit. Methods Enzymol., 210, 87-105.
    • (1992) Methods Enzymol. , vol.210 , pp. 87-105
    • Straume, M.1    Johnson, M.L.2
  • 87
  • 88
    • 0031554875 scopus 로고    scopus 로고
    • An indirect optimization method for biochemical systems: Description of method and application to the maximization of the rate of ethanol, glycerol and carbohydrate production in Saccharomyces cerevisiae
    • Torres, N.V., Voit, E.O., Glez-Alcón, C. and Rodriguez, F. (1997) An indirect optimization method for biochemical systems: Description of method and application to the maximization of the rate of ethanol, glycerol and carbohydrate production in Saccharomyces cerevisiae. Biotech. Bioeng., 55, 758-772.
    • (1997) Biotech. Bioeng. , vol.55 , pp. 758-772
    • Torres, N.V.1    Voit, E.O.2    Glez-Alcón, C.3    Rodriguez, F.4
  • 89
    • 0020694602 scopus 로고
    • Protein engineering
    • Ulmer, K.M. (1983) Protein engineering. Science, 219, 666-671.
    • (1983) Science , vol.219 , pp. 666-671
    • Ulmer, K.M.1
  • 90
    • 0030573816 scopus 로고    scopus 로고
    • What BioTechnologists knew all along...?
    • Westerhoff, H.V. and Kell, D.B. (1996) What BioTechnologists knew all along...? J. Theor. Biol., 182, 411-420.
    • (1996) J. Theor. Biol. , vol.182 , pp. 411-420
    • Westerhoff, H.V.1    Kell, D.B.2
  • 91
    • 0031173707 scopus 로고    scopus 로고
    • Mass spectrometry as a readout of protein structure and function
    • Winston, R.L. and Fitzgerald, M.C. (1997) Mass spectrometry as a readout of protein structure and function. Mass Spectr. Rev., 16, 165-179.
    • (1997) Mass Spectr. Rev. , vol.16 , pp. 165-179
    • Winston, R.L.1    Fitzgerald, M.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.