The fatty liver and insulin resistance

Current Molecular Medicine

Volumn 5, Issue 3, 2005, Pages 287-295

  Yki Jarvinen H ^a   Westerbacka, J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Glucose; Hypertriglyceridemia; Magnetic resonance imaging; Proton spectroscopy

Indexed keywords

ADIPONECTIN; ALANINE AMINOTRANSFERASE; ANTIRETROVIRUS AGENT; ASPARTATE AMINOTRANSFERASE; FATTY ACID; GAMMA GLUTAMYLTRANSFERASE; INSULIN; INSULIN SENSITIZING AGENT; INTERLEUKIN 6; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; TUMOR NECROSIS FACTOR ALPHA;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL CONSUMPTION; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL FEATURE; CLINICAL TRIAL; CORRELATION COEFFICIENT; DIFFERENTIAL DIAGNOSIS; DRUG ABSORPTION; ENZYME ACTIVITY; FAT CONTENT; FAT INTAKE; FATTY ACID BLOOD LEVEL; FATTY LIVER; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GENETIC DISORDER; GENETIC RISK; HEPATOGRAPHY; HIGH RISK PATIENT; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HISTOPATHOLOGY; HIV ASSOCIATED LIPODYSTROPHY; HUMAN; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID ANALYSIS; LIPID METABOLISM; LIPID OXIDATION; LIPID STORAGE; LIVER BIOPSY; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PATHOPHYSIOLOGY; PREDICTION; PROTEIN BLOOD LEVEL; PROTON NUCLEAR MAGNETIC RESONANCE; REVIEW; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SIGNAL TRANSDUCTION; SUBCUTANEOUS FAT; WEIGHT REDUCTION;

ADIPONECTIN; ADIPOSE TISSUE; ALANINE TRANSAMINASE; ANIMALS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CARDIOVASCULAR DISEASES; DIABETES COMPLICATIONS; DISEASE MODELS, ANIMAL; FATTY LIVER; GLUCOSE; HUMANS; INSULIN; INSULIN RESISTANCE; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPODYSTROPHY; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; METFORMIN; OBESITY;

EID: 18644379136     PISSN: 15665240     EISSN: None     Source Type: Journal    
DOI: 10.2174/1566524053766031     Document Type: Review

References (69)

1. Yki-Järvinen, H. (2003) In Textbook of Diabetes. 2 ed. Pickup JC, Williams G, Eds. Oxford, Blackwell, p. 22. 1-20. 19.
2. Reitman, M.L., Arioglu, E., Gavrilova, O., Taylor, S.I. (2000) Trends. Endocrinol. Metab. 11, 410-416.
3. Klein, S., Fontana, L., Young, V.L., Coggan, A.R., Kilo, C., Patterson, B.W. (2004) N. Engl. J. Med. 360, 2549-2557.
4. Reitman, M.L. (2002) Annu. Rev. Nutr. 22, 459-482.
5. Burant, C.F., Sreenan, S., Hirano, K., Tai, T.A., Lohmiller, J., Lukens, J., Davidson, N.O., Ross, S., Graves, R.A. (1997) J. Clin. Invest. 100, 2900-2908.
6. Shimomura, I., Hammer, R.E., Richardson, J.A., Ikemoto, S., Bashmakov, Y., Goldstein, J.L., Brown, M.S. (1998) Genes. Dev. 12, 3182-3194.
7. Moitra, J., Mason, M.M., Olive, M., Krylov, D., Gavrilova, O., Marcus-Samuels, B., Feigenbaum, L., Lee, E., Aoyama, T., Eckhaus, M., Reitman, M. L., Vinson, C. (1998) Genes. Dev. 12, 3168-3181.
8. Kim, J.K., Gavrilova, O., Chen, Y., Reitman, M.L., Shulman, G.I. (2000) J. Biol. Chem. 275, 8456-8460.
9. Gavrilova, O., Marcus-Samuels, B., Graham, D., Kim, J.K., Shulman, G.I., Castle, A.L., Vinson, C., Eckhaus, M., Reitman, M.L. (2000) J. Clin. Invest. 105, 271-278.
10. Gulick, R.M., Mellors, J.W., Havlir, D., Eron, J.J., Gonzalez, C., McMahon, D., Richman, D.D., Valentine, F.T., Jonas, L.: Meibohm, A., Emini, E.A., Chodakewitz, J.A. (1997) N. Engl. J. Med. 337, 734-739.
11. Cameron, D.W., Heath-Chiozzi, M., Danner, S., Cohen, C., Kravcik, S., Maurath, C., Sun, E., Henry, D., Rode, R., Potthoff, A., Leonard, J. (1998) Lancet 351, 543-549.
12. Carr, A., Cooper, DA. (2000) Lancet 356, 1423-1430.
13. Garg, A. (2000) Am. J. Med. 108, 143-152.
14. Szczepaniak, L.S., Babcock, E.E., Schick, F., Dobbins, R.L., Garg, A., Burns, D.K., McGarry, J.D., Stein, D.T. (1999) Am. J. Physiol. 276, E977-E989.
15. Longo, R., Ricci, C., Masutti, F., Vidimari, R., Croce, L.S., Bercich, L., Tiribelli, C., Dalla, P. L. (1993) Invest. Radiol. 28, 297-302.
16. Ryysy, L., Häkkinen, A.M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., Yki-Jar̈vinen, H, (2000) Diabetes 49, 749-758.
17. Joy, D., Thava, V.R., Scott, B.B. (2003) Eur. J. Gastroenterol. Hepatol. 15, 539-543.
18. Piekarski, J., Goldberg, H.I., Royal, S.A., Axel, L., Moss, A.A. (1980) Radiology 137, 727-729.
19. Fong, D.G., Nehra, V., Lindor, K.D., Buchman, A.L. (2000) Hepatology 32, 3-10.
20. Burt, A.D., Mutton, A., Day, C.P. (1998) Semin. Diagn. Pathol. 15, 246-258.
21. Falck-Ytter, Y., Younossi, Z.M., Marchesini, G., McCullough, A.J. (2001) Semin. Liver. Dis. 21, 17-26.
22. Diehl, A.M. (1999) Semin. Liver. Dis. 19, 221-229.
23. Clark, J.M., Diehl, A.M. (2002) Curr. Diab. Rep. 2, 210-215.
24. Seppala-Lindroos, A., Vehkavaara, S., Hakkinen, A.M., Goto, T., Westerbacka, J., Sovijarvi, A., Halavaara, J., Yki-Jarvinen, H. (2002) J. Clin. Endocrinol. Metab. 87, 3023-3028.
25. Tiikkainen, M., Tamminen, M., Hakkinen, A.M., Bergholm, R., Vehkavaara, S., Halavaara, J., Teramo, K., Rissanen, A., Yki-Jarvinen, H. (2002) Obes. Res. 10, 859-867.
26. Kelley, D.E., McKolanis, T.M., Hegazi, R.A., Kuller, L.H., Kalhan, S.C. (2003) Am. J. Physiol. Endocrinol. Metab. 285, E906-E916.
27. Westerbacka, J., Corner, A., Tiikkainen, M., Tamminen, M., Vehkavaara, S., Hakkinen, A.M., Fredriksson, J., Yki-Jarvinen, H. (2004) Diabetologia 47, 1360-1369.
28. Krotkiewski, M., Bjorntorp, P., Sjostrom, L., Smith, U. (1983) J. Clin. Invest. 72, 1150-1162.
29. Frayn, K.N. (2000) Br. J. Nutr. 83 Suppl 1, S71-S77.
30. Hultin, M., Savonen, R., Olivecrona, T. (1996) J. Lipid. Res. 37, 1022-1036.
31. Miles, J.M., Park, Y.S., Walewicz, D., Russell-Lopez, C., Windsor, S., Isley, W.L., Coppack, S.W., Harris, W.S. (2004) Diabetes 53, 521-527.
32. Duee, P.H., Pegorier, J.P., El, M.L., Herbin, C., Kohl, C., Girard, J. (1985) Am. J. Physiol. 249, E478-E484.
33. Heath, R.B., Karpe, F., Milne, R.W., Burdge, G.C., Wootton, S.A., Frayn, K.N. (2003) J. Lipid. Res. 44, 2065-2072.
34. Westerbacka, J., Lammi, K., Häkkinen, A.M., Rissanen, A., Salminen, I., Aro, A., Yki-Järvinen, H. (2005) J. Clin. Endocrinol. Metab. doi:10.1210/jc.2004-1983.
35. Pietiläinen, K.H., Rissanen, A., Kaprio, J., Mäkimattila, S., Häkkinen, A.-M., Westerbacka, J., Sutinen, J., Vehkavaara, S., and Yki-Järvinen, H. (2004) Am. J. Physiol. Endocrinol. Metab. doi:10.1152/ajpendo.00381.2004.
36. Xu, H., Barnes, G.T., Yang, Q., Tan, G., Yang, D., Chou, C.J., Sole, J., Nichols, A., Ross, J.S., Tartaglia, L.A., Chen, H. (2003) J. Clin. Invest. 112, 1821-1830
37. Jan, V., Cervera, P., Maachi, M., Baudrimont, M., Kim, M., Vidal, H., Girard, P.M., Levan, P., Rozenbaum, W., Lombes, A., Capeau, J., Bastard, J.P. (2004) Antivir. Ther. 9, 555-564.
38. Hoffstedt, J., Arvidsson, E., Sjolin, E., Wahlen, K., Arner, P. (2004) J. Clin. Endocrinol. Metab. 89, 1391-1396.
39. Sutinen, J., Korsheninnikova, E., Funahashi, T., Matsuzawa, Y., Nyman, T., Yki-Järvinen, H. (2003) J. Clin. Endocrinol. Metab. 88, 1907-1910.
40. Bruun, J.M., Lihn, A.S., Verdich, C., Pedersen, S.B., Toubro, S., Astrup, A., Richelsen, B. (2003) Am. J. Physiol. Endocrinol. Metab. 285, E527-E533.
41. Yamauchi, T., Kamon, J., Waki, H., Terauchi, Y., Kubota, N., Hara, K., Mori, Y., Die, T., Murakami K., Tsuboyama-Kasaoka, N., Ezaki, O., Akanuma, Y., Gavrilova, O., Vinson, C., Reitman, M.L., Kagechika, H., Shudo, K., Yoda, M., Nakano, Y., Tobe, K., Nagai, R., Kimura, S., Tomita, M., Froguel, P., Kadowaki, T. (2001) Nat Med 7, 941-946.
42. Tiikkainen, M., Häkkinen, A-M., Korsheninnikova, E., Nyman, T., Mäkimattila, S., Yki-Järvinen, H. (2004) Diabetes 53, 2169-2167.
43. Pajvani, U.B., Hawkins, M., Combs, T.P., Raja, M.W., Doebber, T., Berger, J.P., Wagner, J.A., Wu, M., Knopps, A., Xiang, A.H., Utzsheider, K.M., Kahn, S.E., Olefsky, J.M., Buchanan, T.A., Scherer, P.E. (2004) J. Biol. Chem. 279, 12152-12162.
44. Bajaj, M., Suraamornkul, S., Piper, P., Hardies, L.J., Glass, L., Cersosimo, E., Pratipanawatr, T., Miyazaki, Y., DeFronzo, R.A. (2004) J. Clin. Endocrinol. Metab. 89, 200-206.
45. Johanson, E.H., Jansson, P-A., Lonn, L., Matsuzawa, Y., Funahashi, T., Taskinen, M-R., Smith, U., Axelsen, M. (2003) J. Clin. Endocrinol. Metab. 88, 4232-4238.
46. Clark, J.M., Diehl, A-M.B.F.L. (2001) Diabetes 50, A38.
47. Meltzer, A.A., Everhart, J. E. (1997) Am. J. Epidemiol. 146, 565-571.
48. Ohlson, L.O., Larsson, B., Bjorntorp, P., Eriksson, H., Svardsudd, K., Welin, L., Tibblin, G., Wilhelmsen, L. (1988) Diabetologia 31, 798-805.
49. Perry, I.J., Wannamethee, S.G., Shaper, A.G. (1998) Diabetes Care 21, 732-737.
50. Nakanishi, N., Nishina, K., Li, W., Sato, M., Suzuki, K., Tatara, K. (2003) J. Intern. Med. 254, 287-295.
51. Lee, D.H., Jacobs, D.R. Jr., Gross, M., Kiefe, C.I., Roseman, J., Lewis, C.E., Steffes, M. (2003) Clin. Chem. 49, 1358-1366.
52. Lee, D.H., Ha, M.H., Kim, J.H., Christiani, D.C., Gross, M.D., Steffes, M., Blomhoff, R., Jacobs, D.R. Jr. (2003) Diabetologia 46, 359-364.
53. Hanley, A.J., Williams, K., Festa, A., Wagenknecht, L.E., D'Agostino, R.B. Jr., Kempf, J., Zinman, B., Haffner, S.M. (2004) Diabetes 53, 2623-2632.
54. Vozarova, B., Stefan, N., Lindsay, R.S., Saremi, A., Pratley, R.E., Bogardus, C., Tataranni, P.A. (2002) Diabetes 51, 1889-1895.
55. De, M.R., Locatelli, F., Zoppini, G., Verlato, G., Bonora, E., Muggeo, M. (1999) Diabetes Care 22, 756-761.
56. El-Serag, H.B., Everhart, J.E. (2002) Gastroenterology 122, 1822-1828.
57. El-Serag, H.B., Tran, T., Everhart, J.E. (2004) Gastroenterology 126, 460-468.
58. Jackson, R.A., Hawa, I.M., Jaspan, J.B., Sim, B.M., SiSilvio, L., Flatherbe, D., Kurtz, A.B. (1987) Diabetes 36, 632-640.
59. Yki-Järvinen, H., Helve, E., Sane, T., Nurjhan, N., Taskinen, M-R. (1989) Am. J. Physiol. 256, E732-E739.
60. Mitrakou, A., Kelley, D., Veneman, T., Jenssen, T., Pangburn, T., Reilly, T., Gerich, J. (1990) Diabetes 39, 1381-1390.
61. Scheen, A.J., Luyckx, F.H. Best Pract. Res. Clin. Endocrinol. Metab. 16, 703-716.
62. Tiikkainen, M., Bergholm, R., Vehkavaara, S., Rissanen, A., Hakkinen, A.M., Tamminen, M., Teramo, K., Yki-Jarvinen, H. (2003) Diabetes 52, 701-707.
63. Mayerson, A.B., Hundal, R.S., Dufour, S., Lebon, V., Befroy, D., Cline, G.W., Enocksson, S., Inzucchi, S.E., Shulman, G.I. Petersen, K.F. (2002) Diabetes 51, 797-802.
64. Bajaj, M., Suraamornkul, S., Pratipanawatr, T., Hardies, L.J., Pratipanawatr, W., Glass, L., Cersosimo, E., Miyazaki, Y., DeFronzo, R.A. Diabetes 52, 1364-1370.
65. Sutinen, J., Häkkinen, A.M., Westerbacka, J., Seppälä-Lindroos, A., Vehkavaara, S., Halavaara, J., Järvinen, A., Ristola, M., Yki-Järvinen, H. Antivir. Ther. 8, 199-207.
66. Carey, D.G., Cowin, G.J., Galloway, G.J., Jones, N.P., Richards, J.C., Biswas, N., Doddrell, D.M. Obes. Res. 10, 1008-1015.
67. Promrat, K., Lutchman, G., Uwaifo, G.I., Freedman, R.J., Soza, A., Heller, T., Doo, E., Ghany, M., Premkumar, A., Park, Y., Liang, T.J., Yanovski, J.A., Kleiner, D.E., Hoofnagle, J.H. (2004) Hepatology JID-8302946 39, 188-196.
68. Neuschwander-Tetri, B.A., Brunt, E.M., Wehmeier, K.R., Oliver, D., Bacon, B.R. (2003) Hepatology JID-8302946 38, 1008-1017.
69. Yki-Järvinen, H. (2004) N. Engl. J. Med. 351, 1106-1118.