Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice

Diabetes

Volumn 55, Issue 10, 2006, Pages 2843-2848

  Sørensen, Heidi ^a   Brand, Christian L ^a   Neschen, Susanne ^b   Holst, Jens Juul ^c   Fosgerau, Keld ^a   Nishimura, Erica ^a   Shulman, Gerald I ^b  

^a NOVO NORDISK A S   (Denmark)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON; GLUCAGON ANTIBODY; GLYCOGEN; INSULIN; MONOCLONAL ANTIBODY; TRIACYLGLYCEROL; GLUCOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; GLYCEMIC CONTROL; GLYCOGEN SYNTHESIS; INSULIN BLOOD LEVEL; LIVER METABOLISM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; SERODIAGNOSIS; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; DRUG EFFECT; GLYCOGEN LIVER LEVEL; HYPERGLYCEMIA; IMMUNOLOGY; LIVER; MALE; METABOLISM; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCAGON; GLUCOSE; HYPERGLYCEMIA; LIVER; LIVER GLYCOGEN; MALE; MICE; MICE, OBESE;

EID: 33750877987     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0222     Document Type: Article

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