Carboxyl-terminal proteolytic processing of CUX1 by a caspase enables transcriptional activation in proliferating cells

Journal of Biological Chemistry

Volumn 282, Issue 41, 2007, Pages 30216-30226

  Truscott, Mary ^a,b   Denault, Jean Bernard ^c   Goulet, Brigitte ^a,b   Leduy, Lam ^a   Salvesen, Guy S ^c   Nepveu, Alain ^a,b  

^a MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NATURAL CASPASE INHIBITORS; PROTEOLYTIC PROCESSING;

CELLS; ENZYME INHIBITION; PATIENT TREATMENT; TRANSCRIPTION;

PROTEINS;

CUX 1 PROTEIN; ISOPROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ASSAY; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME LOCALIZATION; ENZYME MECHANISM; ENZYME SUBSTRATE; FLUORESCENCE ACTIVATED CELL SORTING; IN VITRO STUDY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN VARIANT; TRANSCRIPTION INITIATION;

ANIMALS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME INHIBITORS; FLUORESCEINS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MODELS, BIOLOGICAL; NIH 3T3 CELLS; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SUCCINIMIDES; THYMIDINE; TRANS-ACTIVATION (GENETICS);

EID: 35648963733     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702328200     Document Type: Article

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