Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion

PLoS Biology

Volumn 5, Issue 10, 2007, Pages 2255-2269

  Du, Yi Chieh Nancy ^a   Lewis, Brian C ^a,c   Hanahan, Douglas ^b   Varmus, Harold ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CADHERIN; CADHERIN 1; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; INSULIN; MYOSIN VA; PROTEIN BCL XL; RETROVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INVASION; CANCER MODEL; CARCINOGENESIS; CELL ASSAY; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CELL TYPE; CONTROLLED STUDY; CYTOSKELETON; DISEASE COURSE; DOWN REGULATION; FLOW CYTOMETRY; GENE TRANSFER; IN VITRO STUDY; LYMPH NODE METASTASIS; MEASUREMENT; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PANCREAS ADENOMA; PANCREAS ISLET CELL CARCINOMA; PANCREAS ISLET CELL HYPERPLASIA; PHENOTYPE; PROMOTER REGION; PROTEIN ANALYSIS; SOMATIC CELL GENETICS; TRANSGENIC MOUSE; TUMOR VASCULARIZATION;

ADENOMA, ISLET CELL; ANIMALS; BCL-X PROTEIN; CADHERINS; CELL MOVEMENT; CELL SHAPE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMANS; ISLETS OF LANGERHANS; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; RATS;

AVES; AVIAN LEUKOSIS VIRUS; MUS; RATTUS; SUBGROUP A;

EID: 35648938726     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050276     Document Type: Article

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